Spem1 (spermatid maturation 1) - Rat Genome Database

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Gene: Spem1 (spermatid maturation 1) Mus musculus
Analyze
Symbol: Spem1
Name: spermatid maturation 1
RGD ID: 1623145
MGI Page MGI
Description: Acts upstream of or within flagellated sperm motility and sperm individualization. Located in cytoplasm. Orthologous to human SPEM1 (spermatid maturation 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 1700095G12Rik; MGC118350; RP23-422L16.22; sperm maturation 1; spermatid maturation protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,711,697 - 69,712,991 (-)NCBIGRCm39mm39
GRCm39 Ensembl1169,711,702 - 69,713,006 (-)Ensembl
GRCm381169,820,871 - 69,822,165 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,820,876 - 69,822,180 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,634,373 - 69,635,667 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,637,066 - 69,638,375 (-)NCBImm8
Celera1177,381,831 - 77,383,125 (-)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:17426145   PMID:20558241   PMID:21184802   PMID:21677750  
PMID:21873635  


Genomics

Comparative Map Data
Spem1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,711,697 - 69,712,991 (-)NCBIGRCm39mm39
GRCm39 Ensembl1169,711,702 - 69,713,006 (-)Ensembl
GRCm381169,820,871 - 69,822,165 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,820,876 - 69,822,180 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,634,373 - 69,635,667 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,637,066 - 69,638,375 (-)NCBImm8
Celera1177,381,831 - 77,383,125 (-)NCBICelera
Cytogenetic Map11B3NCBI
SPEM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,420,324 - 7,421,632 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl177,420,324 - 7,421,632 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,323,643 - 7,324,951 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,264,403 - 7,265,675 (+)NCBINCBI36hg18NCBI36
Celera177,349,564 - 7,350,836 (+)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,217,702 - 7,218,974 (+)NCBIHuRef
CHM1_1177,332,771 - 7,334,043 (+)NCBICHM1_1
T2T-CHM13v2.0177,324,372 - 7,325,680 (+)NCBI
Spem1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,541,454 - 54,542,755 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1054,541,471 - 54,546,131 (-)Ensembl
Rnor_6.01056,428,447 - 56,429,748 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,428,344 - 56,429,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,173,566 - 56,174,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,642,947 - 56,644,248 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1053,695,730 - 53,697,031 (-)NCBICelera
Cytogenetic Map10q24NCBI
Spem1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,503,229 - 9,504,535 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,503,229 - 9,504,535 (-)NCBIChiLan1.0ChiLan1.0
SPEM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,441,032 - 7,442,342 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,441,032 - 7,442,342 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,454,453 - 7,455,791 (+)NCBIMhudiblu_PPA_v0panPan3
SPEM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,354,044 - 32,357,684 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,354,153 - 32,355,401 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,491,884 - 32,493,545 (+)NCBI
ROS_Cfam_1.0532,459,456 - 32,461,117 (+)NCBI
ROS_Cfam_1.0 Ensembl532,459,816 - 32,461,064 (+)Ensembl
UMICH_Zoey_3.1532,424,690 - 32,426,351 (+)NCBI
UNSW_CanFamBas_1.0532,383,422 - 32,385,083 (+)NCBI
UU_Cfam_GSD_1.0532,560,690 - 32,562,351 (+)NCBI
Spem1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,230,596 - 47,232,168 (+)NCBI
SpeTri2.0NW_004936595704,717 - 706,357 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPEM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,796,398 - 6,798,093 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl166,796,842 - 6,798,058 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605914,610,480 - 14,612,166 (-)NCBIVero_WHO_p1.0
Spem1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,034,685 - 10,036,388 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462478610,034,794 - 10,038,171 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
UniSTS:493882  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381169,820,782 - 69,822,265UniSTSGRCm38
MGSCv371169,634,284 - 69,635,767UniSTSGRCm37
Celera1177,381,742 - 77,383,225UniSTS
Cytogenetic Map11B4UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:128
Count of miRNA genes:114
Interacting mature miRNAs:121
Transcripts:ENSMUST00000045771
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000045771   ⟹   ENSMUSP00000037500
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,711,702 - 69,713,006 (-)Ensembl
GRCm38.p6 Ensembl1169,820,876 - 69,822,180 (-)Ensembl
RefSeq Acc Id: NM_028855   ⟹   NP_083131
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,711,697 - 69,712,991 (-)NCBI
GRCm381169,820,871 - 69,822,165 (-)ENTREZGENE
MGSCv371169,634,373 - 69,635,667 (-)RGD
Celera1177,381,831 - 77,383,125 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_083131 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00506 (Get FASTA)   NCBI Sequence Viewer  
  ABO33756 (Get FASTA)   NCBI Sequence Viewer  
  BAB24854 (Get FASTA)   NCBI Sequence Viewer  
  EDL12454 (Get FASTA)   NCBI Sequence Viewer  
  Q5F289 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_083131   ⟸   NM_028855
- UniProtKB: Q5F289 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000037500   ⟸   ENSMUST00000045771

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5F289-F1-model_v2 AlphaFold Q5F289 1-310 view protein structure

Promoters
RGD ID:8675226
Promoter ID:EPDNEW_M15644
Type:multiple initiation site
Name:Spem1_1
Description:Mus musculus sperm maturation 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381169,822,153 - 69,822,213EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921538 AgrOrtholog
Ensembl Genes ENSMUSG00000041165 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000037500 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000045771 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro SPEM1_N UniProtKB/Swiss-Prot
KEGG Report mmu:74288 UniProtKB/Swiss-Prot
MGD MGI:1921538 ENTREZGENE
NCBI Gene 74288 ENTREZGENE
Pfam Spem1 UniProtKB/Swiss-Prot
PhenoGen Spem1 PhenoGen
UniProt Q5F289 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q497J9 UniProtKB/Swiss-Prot
  Q9D9D4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-31 Spem1  spermatid maturation 1  Spem1  sperm maturation 1  Symbol and/or name change 5135510 APPROVED