Dhx57 (DExH-box helicase 57) - Rat Genome Database

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Gene: Dhx57 (DExH-box helicase 57) Mus musculus
Analyze
Symbol: Dhx57
Name: DExH-box helicase 57 (Ensembl:DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57)
RGD ID: 1623041
MGI Page MGI
Description: Predicted to enable RNA binding activity and helicase activity. Is expressed in central nervous system and retina. Orthologous to human DHX57 (DExH-box helicase 57).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW494914; DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57; DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 homolog; DEAH box protein 57; MGC77974; putative ATP-dependent RNA helicase DHX57
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391780,545,733 - 80,597,620 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1780,545,738 - 80,597,905 (-)EnsemblGRCm39 Ensembl
GRCm381780,238,304 - 80,290,476 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1780,238,309 - 80,290,476 (-)EnsemblGRCm38mm10GRCm38
MGSCv371780,637,644 - 80,689,816 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361780,146,635 - 80,198,802 (-)NCBIMGSCv36mm8
Celera1784,555,608 - 84,608,242 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1750.63NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15618518   PMID:16141072  
PMID:16141073   PMID:16602821   PMID:17967808   PMID:18799693   PMID:21267068   PMID:21873635   PMID:26206133   PMID:31040226   PMID:31138677   PMID:32325033   PMID:34321999   PMID:37839992  


Genomics

Comparative Map Data
Dhx57
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391780,545,733 - 80,597,620 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1780,545,738 - 80,597,905 (-)EnsemblGRCm39 Ensembl
GRCm381780,238,304 - 80,290,476 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1780,238,309 - 80,290,476 (-)EnsemblGRCm38mm10GRCm38
MGSCv371780,637,644 - 80,689,816 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361780,146,635 - 80,198,802 (-)NCBIMGSCv36mm8
Celera1784,555,608 - 84,608,242 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1750.63NCBI
DHX57
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38238,797,729 - 38,875,934 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl238,797,729 - 38,875,934 (-)EnsemblGRCh38hg38GRCh38
GRCh37239,024,871 - 39,103,075 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36238,878,375 - 38,956,525 (-)NCBINCBI36Build 36hg18NCBI36
Celera238,865,894 - 38,943,735 (-)NCBICelera
Cytogenetic Map2p22.1NCBI
HuRef238,763,646 - 38,841,511 (-)NCBIHuRef
CHM1_1238,955,699 - 39,033,494 (-)NCBICHM1_1
T2T-CHM13v2.0238,806,517 - 38,884,496 (-)NCBIT2T-CHM13v2.0
Dhx57
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8620,474,889 - 20,528,556 (+)NCBIGRCr8
mRatBN7.2614,725,305 - 14,776,321 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl614,725,303 - 14,776,321 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx615,032,188 - 15,074,849 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0615,353,675 - 15,396,927 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0614,849,948 - 14,893,200 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.062,921,340 - 2,961,397 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl62,921,299 - 2,961,510 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.062,898,233 - 2,948,505 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.463,139,942 - 3,183,171 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.163,140,433 - 3,183,171 (-)NCBI
Celera614,410,057 - 14,453,286 (+)NCBICelera
Cytogenetic Map6q12NCBI
Dhx57
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554416,477,521 - 6,541,994 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554416,479,107 - 6,541,281 (-)NCBIChiLan1.0ChiLan1.0
DHX57
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21287,592,752 - 87,670,890 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A87,596,717 - 87,674,866 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A38,835,346 - 38,913,499 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A39,591,612 - 39,668,593 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A39,591,619 - 39,668,282 (-)Ensemblpanpan1.1panPan2
DHX57
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11730,855,443 - 30,913,754 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1730,856,552 - 30,905,501 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1730,671,439 - 30,729,928 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01731,511,223 - 31,569,533 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1731,512,311 - 31,569,511 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11730,733,023 - 30,791,471 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01730,802,752 - 30,861,052 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01731,016,166 - 31,074,493 (-)NCBIUU_Cfam_GSD_1.0
Dhx57
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629240,951,261 - 41,007,278 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650812,379,323 - 12,439,874 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650812,379,951 - 12,436,076 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX57
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3101,458,930 - 101,533,147 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13101,458,854 - 101,533,160 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23107,850,435 - 107,860,794 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHX57
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11468,509,127 - 68,583,741 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1468,509,414 - 68,584,276 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604543,396,825 - 43,471,949 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhx57
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473820,299,602 - 20,360,844 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473820,299,096 - 20,368,142 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dhx57
1898 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:522
Count of miRNA genes:216
Interacting mature miRNAs:241
Transcripts:ENSMUST00000038166, ENSMUST00000086555
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
1357754Ahl3_mage related hearing loss 3 (mouse)Not determined175020395784204103Mouse
4141879Chlq9_mcirculating hormone level QTL 9 (mouse)Not determined175175842585758612Mouse
1357532Bmch7_mbone mechanical trait 7 (mouse)Not determined175175842585758612Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175710765191107803Mouse
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175710765191107803Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175710765191107803Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175710765191107803Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175710765191107803Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175710765191107803Mouse
4142201Obrq15_mobesity resistance QTL 15 (mouse)Not determined5753444780885776Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175753444793507179Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5758908991589197Mouse
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176230101095294699Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176230101095294699Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176388554895294699Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176521493895294699Mouse
14928308Manh82_mmandible shape 82 (mouse)176631524395294699Mouse
13464254Ifvrq3_minfluenza virus resistance QTL 3 (mouse)176795765583908089Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176894131995294699Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177070119895294699Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177070119895294699Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177070119895294699Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177070119895294699Mouse
1357528Nhdlq3_mnon-HDL QTL 3 (mouse)Not determined177339513295294699Mouse
4141195Nilac11_mnicotine induced locomotor activity 11 (mouse)Not determined177339513295294699Mouse
4141697Hbnr3_mHeligmosomoides bakeri nematode resistance 3 (mouse)Not determined7410765193507179Mouse
1357646Axtq3_manxiety QTL 3 (mouse)Not determined177458908990395270Mouse
1357552Aaj4_manxiety in A/J 4 (mouse)Not determined177458908990395270Mouse

Markers in Region
AW494914  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381780,238,392 - 80,238,490UniSTSGRCm38
MGSCv371780,637,732 - 80,637,830UniSTSGRCm37
Celera1784,555,696 - 84,555,794UniSTS
Cytogenetic Map17E3UniSTS
Whitehead/MRC_RH17967.57UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003952074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC132910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW488262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000038166   ⟹   ENSMUSP00000041069
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1780,545,738 - 80,597,905 (-)Ensembl
GRCm38.p6 Ensembl1780,238,309 - 80,290,476 (-)Ensembl
RefSeq Acc Id: ENSMUST00000086555   ⟹   ENSMUSP00000083742
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1780,545,740 - 80,597,572 (-)Ensembl
GRCm38.p6 Ensembl1780,238,311 - 80,290,143 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234703
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1780,572,504 - 80,578,012 (-)Ensembl
GRCm38.p6 Ensembl1780,265,075 - 80,270,583 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234733
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1780,559,994 - 80,597,303 (-)Ensembl
GRCm38.p6 Ensembl1780,252,565 - 80,289,874 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235024
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1780,571,376 - 80,575,271 (-)Ensembl
GRCm38.p6 Ensembl1780,263,947 - 80,267,842 (-)Ensembl
RefSeq Acc Id: NM_001163759   ⟹   NP_001157231
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,740 - 80,597,605 (-)NCBI
GRCm381780,238,304 - 80,290,476 (-)ENTREZGENE
MGSCv371780,637,644 - 80,689,816 (-)RGD
Celera1784,555,608 - 84,608,242 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001410326   ⟹   NP_001397255
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,740 - 80,597,605 (-)NCBI
RefSeq Acc Id: NM_001410327   ⟹   NP_001397256
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,740 - 80,597,605 (-)NCBI
RefSeq Acc Id: NM_001410328   ⟹   NP_001397257
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,740 - 80,597,605 (-)NCBI
RefSeq Acc Id: NM_198942   ⟹   NP_945180
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,740 - 80,597,605 (-)NCBI
GRCm381780,238,304 - 80,290,476 (-)ENTREZGENE
MGSCv371780,637,644 - 80,689,816 (-)RGD
Celera1784,555,608 - 84,608,242 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030249433   ⟹   XP_030105293
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,733 - 80,597,573 (-)NCBI
GRCm381780,238,304 - 80,290,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249434   ⟹   XP_030105294
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,733 - 80,597,485 (-)NCBI
GRCm381780,238,304 - 80,290,182 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249435   ⟹   XP_030105295
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,733 - 80,597,485 (-)NCBI
GRCm381780,238,304 - 80,290,181 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249436   ⟹   XP_030105296
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,733 - 80,597,486 (-)NCBI
GRCm381780,238,304 - 80,290,057 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249437   ⟹   XP_030105297
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,733 - 80,597,573 (-)NCBI
GRCm381780,238,304 - 80,290,180 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160254   ⟹   XP_036016147
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,559,817 - 80,597,620 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160255   ⟹   XP_036016148
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,545,733 - 80,597,579 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003952074
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391780,557,524 - 80,597,620 (-)NCBI
GRCm381780,253,262 - 80,290,196 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_945180   ⟸   NM_198942
- Peptide Label: isoform 2
- UniProtKB: Q6P5D3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001157231   ⟸   NM_001163759
- Peptide Label: isoform 1
- UniProtKB: Q8BIA2 (UniProtKB/Swiss-Prot),   Q8BI63 (UniProtKB/Swiss-Prot),   Q6P1B4 (UniProtKB/Swiss-Prot),   Q6NZK4 (UniProtKB/Swiss-Prot),   Q3TS93 (UniProtKB/Swiss-Prot),   Q8R360 (UniProtKB/Swiss-Prot),   Q6P5D3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030105293   ⟸   XM_030249433
- Peptide Label: isoform X3
RefSeq Acc Id: XP_030105294   ⟸   XM_030249434
- Peptide Label: isoform X3
RefSeq Acc Id: XP_030105295   ⟸   XM_030249435
- Peptide Label: isoform X4
RefSeq Acc Id: XP_030105297   ⟸   XM_030249437
- Peptide Label: isoform X6
RefSeq Acc Id: XP_030105296   ⟸   XM_030249436
- Peptide Label: isoform X4
RefSeq Acc Id: ENSMUSP00000083742   ⟸   ENSMUST00000086555
RefSeq Acc Id: ENSMUSP00000041069   ⟸   ENSMUST00000038166
RefSeq Acc Id: XP_036016148   ⟸   XM_036160255
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036016147   ⟸   XM_036160254
- Peptide Label: isoform X5
RefSeq Acc Id: NP_001397257   ⟸   NM_001410328
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001397256   ⟸   NM_001410327
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001397255   ⟸   NM_001410326
- Peptide Label: isoform 1
- UniProtKB: Q8BIA2 (UniProtKB/Swiss-Prot),   Q8BI63 (UniProtKB/Swiss-Prot),   Q6P5D3 (UniProtKB/Swiss-Prot),   Q6P1B4 (UniProtKB/Swiss-Prot),   Q6NZK4 (UniProtKB/Swiss-Prot),   Q3TS93 (UniProtKB/Swiss-Prot),   Q8R360 (UniProtKB/Swiss-Prot)
Protein Domains
Helicase ATP-binding   Helicase C-terminal   UBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P5D3-F1-model_v2 AlphaFold Q6P5D3 1-1388 view protein structure

Promoters
RGD ID:13676850
Promoter ID:EPDNEW_M22574
Type:single initiation site
Name:Dhx57_1
Description:Mus musculus DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 ,transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381780,289,813 - 80,289,873EPDNEW
RGD ID:6827993
Promoter ID:MM_KWN:24274
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:UC008DQX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361780,648,961 - 80,649,461 (-)MPROMDB
RGD ID:6827997
Promoter ID:MM_KWN:24275
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:UC008DQY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361780,652,156 - 80,652,656 (-)MPROMDB
RGD ID:6827998
Promoter ID:MM_KWN:24276
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Liver,   Lung,   MEF_B4
Transcripts:NM_001163759,   NM_198942,   UC008DRB.1,   UC008DRC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361780,689,156 - 80,689,656 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2147067 AgrOrtholog
Ensembl Genes ENSMUSG00000035051 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000038166 ENTREZGENE
  ENSMUST00000038166.9 UniProtKB/Swiss-Prot
  ENSMUST00000086555 ENTREZGENE
  ENSMUST00000086555.11 UniProtKB/Swiss-Prot
  ENSMUST00000234733 ENTREZGENE
Gene3D-CATH 1.20.120.1080 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot
  Zinc finger, CCCH-type UniProtKB/Swiss-Prot
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  DHX57_UBA UniProtKB/Swiss-Prot
  DUF1605 UniProtKB/Swiss-Prot
  HA2_WH UniProtKB/Swiss-Prot
  Helicase-assoc_dom UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  RWD-domain UniProtKB/Swiss-Prot
  UBA UniProtKB/Swiss-Prot
  UBA-like_sf UniProtKB/Swiss-Prot
  Znf_CCCH UniProtKB/Swiss-Prot
  Znf_CCCH_sf UniProtKB/Swiss-Prot
KEGG Report mmu:106794 UniProtKB/Swiss-Prot
MGD MGI:2147067 ENTREZGENE
NCBI Gene 106794 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/Swiss-Prot
  ATP-DEPENDENT RNA HELICASE DHX57-RELATED UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  HA2 UniProtKB/Swiss-Prot
  HA2_C UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  OB_NTP_bind UniProtKB/Swiss-Prot
  RWD UniProtKB/Swiss-Prot
  zf-CCCH UniProtKB/Swiss-Prot
PhenoGen Dhx57 PhenoGen
PROSITE HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
  UBA UniProtKB/Swiss-Prot
  ZF_C3H1 UniProtKB/Swiss-Prot
SMART DEXDc UniProtKB/Swiss-Prot
  HA2 UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
  UBA UniProtKB/Swiss-Prot
  ZnF_C3H1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46934 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
  SSF90229 UniProtKB/Swiss-Prot
UniProt DHX57_MOUSE UniProtKB/Swiss-Prot
  Q3TS93 ENTREZGENE
  Q6NZK4 ENTREZGENE
  Q6P1B4 ENTREZGENE
  Q6P5D3 ENTREZGENE
  Q8BI63 ENTREZGENE
  Q8BIA2 ENTREZGENE
  Q8R360 ENTREZGENE
UniProt Secondary Q3TS93 UniProtKB/Swiss-Prot
  Q6NZK4 UniProtKB/Swiss-Prot
  Q6P1B4 UniProtKB/Swiss-Prot
  Q8BI63 UniProtKB/Swiss-Prot
  Q8BIA2 UniProtKB/Swiss-Prot
  Q8R360 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Dhx57  DExH-box helicase 57  Dhx57  DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57  Symbol and/or name change 5135510 APPROVED