![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Celf4 | Mouse | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of CELF4 mRNA | CTD | PMID:28960355 | Celf4 | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of CELF4 mRNA | CTD | PMID:22206623 | Celf4 | Mouse | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of CELF4 mRNA | CTD | PMID:19484750 | Celf4 | Mouse | 17beta-estradiol 3-benzoate | increases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | estradiol 3-benzoate results in increased expression of CELF4 mRNA | CTD | PMID:32741896 | Celf4 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CELF4 promoter] | CTD | PMID:19654925 | Celf4 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CELF4 mRNA | CTD | PMID:32109520 | Celf4 | Mouse | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of CELF4 mRNA | CTD | PMID:30071829 | Celf4 | Mouse | 4,4'-sulfonyldiphenol | decreases expression | EXP | | 6480464 | bisphenol S results in decreased expression of CELF4 mRNA | CTD | PMID:30951980 | Celf4 | Mouse | 4,4'-sulfonyldiphenol | affects methylation | ISO | CELF4 (Homo sapiens) | 6480464 | bisphenol S affects the methylation of CELF4 gene | CTD | PMID:31601247 | Celf4 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | CELF4 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of CELF4 gene | CTD | PMID:31601247 | Celf4 | Mouse | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of CELF4 mRNA | CTD | PMID:28973697 | Celf4 | Mouse | 5-aza-2'-deoxycytidine | decreases methylation | EXP | | 6480464 | Decitabine results in decreased methylation of CELF4 gene | CTD | PMID:27923600 | Celf4 | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of CELF4 mRNA | CTD | PMID:24780913 and PMID:36843608 | Celf4 | Mouse | 6-propyl-2-thiouracil | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of CELF4 mRNA | CTD | PMID:30047161 | Celf4 | Mouse | aflatoxin B1 | decreases methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CELF4 gene | CTD | PMID:27153756 | Celf4 | Mouse | aflatoxin B1 | increases methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of CELF4 intron | CTD | PMID:30157460 | Celf4 | Mouse | Aflatoxin B2 alpha | affects methylation | ISO | CELF4 (Homo sapiens) | 6480464 | aflatoxin B2 affects the methylation of CELF4 intron | CTD | PMID:30157460 | Celf4 | Mouse | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELF4 mRNA | CTD | PMID:37567420 | Celf4 | Mouse | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of CELF4 mRNA | CTD | PMID:16604517 | Celf4 | Mouse | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of CELF4 mRNA | CTD | PMID:36189433 | Celf4 | Mouse | all-trans-retinoic acid | multiple interactions | EXP | | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CELF4 mRNA | CTD | PMID:36189433 | Celf4 | Mouse | amitrole | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of CELF4 mRNA | CTD | PMID:30047161 | Celf4 | Mouse | antirheumatic drug | increases expression | ISO | CELF4 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of CELF4 mRNA | CTD | PMID:24449571 | Celf4 | Mouse | arsane | affects methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of CELF4 gene | CTD | PMID:25304211 | Celf4 | Mouse | arsenic atom | affects methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of CELF4 gene | CTD | PMID:25304211 | Celf4 | Mouse | arsenite(3-) | increases methylation | ISO | CELF4 (Homo sapiens) | 6480464 | arsenite results in increased methylation of CELF4 promoter | CTD | PMID:23974009 | Celf4 | Mouse | atrazine | affects methylation | ISO | Celf4 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of CELF4 gene | CTD | PMID:35440735 | Celf4 | Mouse | benzo[a]pyrene | affects methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CELF4 exon more ... | CTD | PMID:27901495 and PMID:30157460 | Celf4 | Mouse | benzo[a]pyrene | decreases methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of CELF4 3' UTR | CTD | PMID:27901495 | Celf4 | Mouse | benzo[a]pyrene | increases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in increased expression of CELF4 mRNA | CTD | PMID:21839799 | Celf4 | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to CELF4 promoter] | CTD | PMID:19654925 | Celf4 | Mouse | benzo[e]pyrene | affects methylation | ISO | CELF4 (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of CELF4 intron | CTD | PMID:30157460 | Celf4 | Mouse | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA] | CTD | PMID:33484791 | Celf4 | Mouse | bisphenol A | affects expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of CELF4 mRNA | CTD | PMID:25181051 | Celf4 | Mouse | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CELF4 mRNA | CTD | PMID:32156529 | Celf4 | Mouse | bisphenol A | decreases methylation | ISO | CELF4 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of CELF4 gene | CTD | PMID:31601247 | Celf4 | Mouse | bisphenol A | increases methylation | ISO | Celf4 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of CELF4 gene | CTD | PMID:28505145 | Celf4 | Mouse | bisphenol F | decreases expression | EXP | | 6480464 | bisphenol F results in decreased expression of CELF4 mRNA | CTD | PMID:30951980 | Celf4 | Mouse | butanal | increases expression | ISO | CELF4 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of CELF4 mRNA | CTD | PMID:26079696 | Celf4 | Mouse | CGP 52608 | multiple interactions | ISO | CELF4 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CELF4 gene] | CTD | PMID:28238834 | Celf4 | Mouse | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CELF4 gene | CTD | PMID:20938992 | Celf4 | Mouse | cobalt atom | increases expression | EXP | | 6480464 | Cobalt results in increased expression of CELF4 mRNA | CTD | PMID:34468815 | Celf4 | Mouse | D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELF4 mRNA | CTD | PMID:37567420 | Celf4 | Mouse | dorsomorphin | multiple interactions | ISO | CELF4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CELF4 mRNA | CTD | PMID:27188386 | Celf4 | Mouse | entinostat | decreases expression | ISO | CELF4 (Homo sapiens) | 6480464 | entinostat results in decreased expression of CELF4 mRNA | CTD | PMID:27188386 | Celf4 | Mouse | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of CELF4 mRNA | CTD | PMID:30319688 | Celf4 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CELF4 gene | CTD | PMID:20938992 | Celf4 | Mouse | fructose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELF4 mRNA | CTD | PMID:37567420 | Celf4 | Mouse | fulvestrant | multiple interactions | ISO | CELF4 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of CELF4 gene | CTD | PMID:31601247 | Celf4 | Mouse | glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELF4 mRNA | CTD | PMID:37567420 | Celf4 | Mouse | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CELF4 gene | CTD | PMID:20938992 | Celf4 | Mouse | methapyrilene | affects methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of CELF4 intron | CTD | PMID:30157460 | Celf4 | Mouse | methimazole | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of CELF4 mRNA | CTD | PMID:30047161 | Celf4 | Mouse | methoxychlor | affects methylation | ISO | Celf4 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of CELF4 gene | CTD | PMID:35440735 | Celf4 | Mouse | methylmercury chloride | increases expression | ISO | CELF4 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of CELF4 mRNA | CTD | PMID:23179753 | Celf4 | Mouse | mono(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CELF4 mRNA | CTD | PMID:36189433 | Celf4 | Mouse | paracetamol | decreases expression | ISO | CELF4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of CELF4 mRNA | CTD | PMID:22230336 and PMID:26690555 | Celf4 | Mouse | pentanal | increases expression | ISO | CELF4 (Homo sapiens) | 6480464 | pentanal results in increased expression of CELF4 mRNA | CTD | PMID:26079696 | Celf4 | Mouse | propanal | increases expression | ISO | CELF4 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of CELF4 mRNA | CTD | PMID:26079696 | Celf4 | Mouse | propiconazole | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | propiconazole results in decreased expression of CELF4 mRNA | CTD | PMID:30047161 | Celf4 | Mouse | rotenone | decreases expression | ISO | CELF4 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of CELF4 mRNA | CTD | PMID:29955902 | Celf4 | Mouse | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | CELF4 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in decreased expression of CELF4 mRNA | CTD | PMID:35811015 | Celf4 | Mouse | SB 431542 | multiple interactions | ISO | CELF4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CELF4 mRNA | CTD | PMID:27188386 | Celf4 | Mouse | silicon dioxide | decreases expression | ISO | CELF4 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of CELF4 mRNA | CTD | PMID:28425640 | Celf4 | Mouse | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of CELF4 mRNA | CTD | PMID:27862939 | Celf4 | Mouse | streptozocin | multiple interactions | EXP | | 6480464 | [Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA and Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA] | CTD | PMID:33484791 | Celf4 | Mouse | sulfadimethoxine | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of CELF4 mRNA | CTD | PMID:30047161 | Celf4 | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of CELF4 gene and titanium dioxide results in decreased methylation of CELF4 promoter | CTD | PMID:35295148 | Celf4 | Mouse | titanium dioxide | increases methylation | EXP | | 6480464 | titanium dioxide results in increased methylation of CELF4 gene | CTD | PMID:35295148 | Celf4 | Mouse | trichloroethene | decreases expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of CELF4 mRNA | CTD | PMID:33387578 | Celf4 | Mouse | triclosan | increases expression | ISO | CELF4 (Homo sapiens) | 6480464 | Triclosan results in increased expression of CELF4 mRNA | CTD | PMID:30510588 | Celf4 | Mouse | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of CELF4 mRNA | CTD | PMID:33045310 | Celf4 | Mouse | valproic acid | increases methylation | ISO | CELF4 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of CELF4 gene | CTD | PMID:29154799 | Celf4 | Mouse | valproic acid | multiple interactions | ISO | CELF4 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CELF4 mRNA | CTD | PMID:27188386 | Celf4 | Mouse | valproic acid | increases expression | ISO | CELF4 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CELF4 mRNA | CTD | PMID:24383497 more ... | Celf4 | Mouse | valproic acid | affects expression | ISO | CELF4 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CELF4 mRNA | CTD | PMID:25979313 | Celf4 | Mouse | vinclozolin | affects expression | ISO | Celf4 (Rattus norvegicus) | 6480464 | vinclozolin affects the expression of CELF4 mRNA | CTD | PMID:19015723 | Celf4 | Mouse | vorinostat | decreases expression | ISO | CELF4 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of CELF4 mRNA | CTD | PMID:27188386 | |