Tbc1d4 (TBC1 domain family, member 4) - Rat Genome Database

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Gene: Tbc1d4 (TBC1 domain family, member 4) Mus musculus
Analyze
Symbol: Tbc1d4
Name: TBC1 domain family, member 4
RGD ID: 1623009
MGI Page MGI
Description: Predicted to have GTPase activator activity. Predicted to be involved in several processes, including activation of GTPase activity; cellular response to insulin stimulus; and negative regulation of vesicle fusion. Predicted to localize to cytosol and vesicle. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in acanthosis nigricans. Orthologous to human TBC1D4 (TBC1 domain family member 4); PARTICIPATES IN altered insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5930406J04Rik; A930035N22; akt substrate of 160 kDa; AS1; As160; AV295684; KIAA0603; TBC1 domain family member 4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914101,679,796 - 101,846,717 (-)NCBIGRCm39mm39
GRCm39 Ensembl14101,679,796 - 101,846,627 (-)Ensembl
GRCm3814101,442,360 - 101,609,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14101,442,360 - 101,609,191 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714101,841,577 - 102,008,408 (-)NCBIGRCm37mm9NCBIm37
MGSCv3614100,325,233 - 100,494,965 (-)NCBImm8
Celera14100,079,886 - 100,248,354 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-colchicine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
AICA ribonucleotide  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
arotinoid acid  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[ghi]perylene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
carbon nanotube  (EXP)
ciglitazone  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucose  (ISO)
dioxygen  (EXP)
dorsomorphin  (EXP,ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
fenvalerate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
ginsenoside Re  (EXP)
glucose  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
L-ascorbic acid  (ISO)
metformin  (EXP)
methamphetamine  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
PCB138  (EXP)
pirinixic acid  (EXP)
quercetin  (EXP)
SB 431542  (ISO)
streptozocin  (EXP)
succimer  (EXP)
sunitinib  (ISO)
testosterone  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vincristine  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11829485   PMID:11994271   PMID:12466851   PMID:12477932   PMID:12637568   PMID:15254270   PMID:15451025   PMID:15489334  
PMID:15919790   PMID:16055084   PMID:16141072   PMID:16141073   PMID:16154996   PMID:16213228   PMID:16615898   PMID:16762977   PMID:16804075   PMID:16804077   PMID:16880201   PMID:16935857  
PMID:16944949   PMID:17403373   PMID:17717281   PMID:17761952   PMID:18063571   PMID:18076383   PMID:18258599   PMID:18276765   PMID:18511518   PMID:18650435   PMID:18801932   PMID:19532121  
PMID:19923418   PMID:20410134   PMID:21195350   PMID:21267068   PMID:21501347   PMID:21511697   PMID:21613213   PMID:21873635   PMID:22253718   PMID:22315395   PMID:22318952   PMID:22466139  
PMID:22689584   PMID:23011063   PMID:23045393   PMID:23078342   PMID:23804653   PMID:24194600   PMID:24349514   PMID:25158853   PMID:25249576   PMID:25788531   PMID:25923736   PMID:26336159  
PMID:26625902   PMID:27152871   PMID:27554475   PMID:27597886   PMID:27626380   PMID:27929607   PMID:29170369   PMID:29481597   PMID:29669786   PMID:29773651   PMID:30257216   PMID:31175100  
PMID:32325033   PMID:32868338  


Genomics

Comparative Map Data
Tbc1d4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914101,679,796 - 101,846,717 (-)NCBIGRCm39mm39
GRCm39 Ensembl14101,679,796 - 101,846,627 (-)Ensembl
GRCm3814101,442,360 - 101,609,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14101,442,360 - 101,609,191 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714101,841,577 - 102,008,408 (-)NCBIGRCm37mm9NCBIm37
MGSCv3614100,325,233 - 100,494,965 (-)NCBImm8
Celera14100,079,886 - 100,248,354 (-)NCBICelera
Cytogenetic Map14E2.3NCBI
TBC1D4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1375,283,503 - 75,482,169 (-)EnsemblGRCh38hg38GRCh38
GRCh381375,283,503 - 75,483,144 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371375,857,639 - 76,056,305 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361374,756,810 - 74,954,251 (-)NCBINCBI36hg18NCBI36
Build 341374,757,253 - 74,954,251NCBI
Celera1356,756,694 - 56,954,119 (-)NCBI
Cytogenetic Map13q22.2NCBI
HuRef1356,556,159 - 56,753,666 (-)NCBIHuRef
CHM1_11375,826,526 - 76,024,040 (-)NCBICHM1_1
Tbc1d4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21578,256,030 - 78,434,168 (-)NCBI
Rnor_6.0 Ensembl1585,930,044 - 86,105,273 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01585,927,978 - 86,105,829 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01589,695,614 - 89,871,879 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41585,359,159 - 85,561,229 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1577,452,014 - 77,628,396 (-)NCBICelera
Cytogenetic Map15q21NCBI
Tbc1d4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540431,622,102 - 31,691,517 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540431,516,727 - 31,691,414 (+)NCBIChiLan1.0ChiLan1.0
TBC1D4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11375,282,441 - 75,480,138 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1375,282,441 - 75,361,729 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01356,513,065 - 56,706,491 (-)NCBIMhudiblu_PPA_v0panPan3
TBC1D4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12229,109,079 - 29,175,357 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2229,110,201 - 29,290,154 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2228,971,148 - 29,151,992 (-)NCBI
ROS_Cfam_1.02229,444,745 - 29,625,974 (-)NCBI
UMICH_Zoey_3.12229,095,512 - 29,277,006 (-)NCBI
UNSW_CanFamBas_1.02229,139,459 - 29,320,685 (-)NCBI
UU_Cfam_GSD_1.02229,208,132 - 29,388,931 (-)NCBI
Tbc1d4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945130,255,477 - 130,441,705 (+)NCBI
SpeTri2.0NW_0049365115,789,683 - 5,858,930 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1147,543,814 - 47,818,561 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11147,543,808 - 47,760,928 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21152,161,139 - 52,187,164 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1354,384,597 - 54,588,842 (-)NCBI
ChlSab1.1 Ensembl354,386,342 - 54,464,531 (-)Ensembl
Tbc1d4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475124,999,301 - 25,183,905 (+)NCBI

Position Markers
D14Mit176  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3814101,601,118 - 101,601,241UniSTSGRCm38
MGSCv3714102,000,335 - 102,000,458UniSTSGRCm37
Celera14100,240,281 - 100,240,404UniSTS
Cytogenetic Map14E2.3UniSTS
cM Map1448.0UniSTS
Whitehead Genetic1459.0UniSTS
Whitehead/MRC_RH141057.17UniSTS
Whitehead_YAC14 UniSTS
Tbc1d4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14E2.3UniSTS
cM Map14 UniSTS
D14Mit8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3814101,536,132 - 101,536,335UniSTSGRCm38
MGSCv3714101,935,349 - 101,935,552UniSTSGRCm37
Celera14100,175,566 - 100,175,769UniSTS
Cytogenetic Map14E2.3UniSTS
cM Map1448.2UniSTS
Whitehead Genetic1459.0UniSTS
Whitehead_YAC14 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1457942183101622037Mouse
14747006Mancz12_mmandible centroid size 12 (mouse)1469834541103834541Mouse
10054475Ossc3_mosteosarcoma susceptibility 3 (mouse)Not determined1470626332104626490Mouse
1300551Lprm3_mlymphoproliferation modifier 3 (mouse)Not determined1470983788104983908Mouse
1301844Pgia29_mproteoglycan induced arthritis 29 (mouse)Not determined1474114860108114948Mouse
1558819Ossc2_mosteosarcoma susceptibility 2 (mouse)Not determined1474157540108157657Mouse
14928314Manh77_mmandible shape 77 (mouse)1476530354110530354Mouse
1558823Tbbmd6_mtotal body bone mineral density 6 (mouse)Not determined1476836260110836351Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1482924828116925025Mouse
4142508Tgq25_mtriglyceride QTL 25 (mouse)Not determined84896632118896632Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2657
Count of miRNA genes:763
Interacting mature miRNAs:1034
Transcripts:ENSMUST00000100340, ENSMUST00000159484, ENSMUST00000159664, ENSMUST00000159668, ENSMUST00000159951, ENSMUST00000160297, ENSMUST00000160473, ENSMUST00000161304, ENSMUST00000161991, ENSMUST00000162617
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001781101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK031120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB238202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC042747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC080762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01040287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01040302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01040305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01040308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01151598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01151600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT573019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT573033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000100340   ⟹   ENSMUSP00000097913
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,462,974 - 101,609,191 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159484
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,462,794 - 101,608,667 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159664   ⟹   ENSMUSP00000124734
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,462,963 - 101,501,108 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159668
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,462,794 - 101,608,667 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159951   ⟹   ENSMUSP00000124511
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,442,368 - 101,507,326 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160297
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,462,572 - 101,608,832 (-)Ensembl
RefSeq Acc Id: ENSMUST00000160473
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,504,707 - 101,507,270 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161304
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,442,368 - 101,463,223 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161991   ⟹   ENSMUSP00000125509
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,442,360 - 101,609,033 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162617   ⟹   ENSMUSP00000124909
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl14101,443,723 - 101,608,486 (-)Ensembl
RefSeq Acc Id: NM_001081278   ⟹   NP_001074747
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,796 - 101,846,627 (-)NCBI
GRCm3814101,442,360 - 101,609,191 (-)NCBI
MGSCv3714101,841,577 - 102,008,408 (-)RGD
Celera14100,079,886 - 100,248,354 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518759   ⟹   XP_006518822
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
GRCm3814101,442,364 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518760   ⟹   XP_006518823
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
GRCm3814101,442,364 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518761   ⟹   XP_006518824
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
GRCm3814101,442,364 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518762   ⟹   XP_006518825
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
GRCm3814101,442,364 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518763   ⟹   XP_006518826
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
GRCm3814101,442,364 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518764   ⟹   XP_006518827
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,686,010 - 101,846,717 (-)NCBI
GRCm3814101,448,566 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518766   ⟹   XP_006518829
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,708,407 - 101,846,717 (-)NCBI
GRCm3814101,470,978 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006518767   ⟹   XP_006518830
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,716,553 (-)NCBI
GRCm3814101,442,364 - 101,478,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245002   ⟹   XP_011243304
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,700,306 - 101,846,717 (-)NCBI
GRCm3814101,462,870 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315935   ⟹   XP_017171424
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
GRCm3814101,442,364 - 101,609,281 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315937   ⟹   XP_017171426
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,749,076 (-)NCBI
GRCm3814101,442,364 - 101,511,646 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017315938   ⟹   XP_017171427
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,698,165 (-)NCBI
GRCm3814101,442,364 - 101,460,729 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030247707   ⟹   XP_030103567
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,749,036 (-)NCBI
GRCm3814101,442,364 - 101,511,630 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036158529   ⟹   XP_036014422
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
RefSeq Acc Id: XR_001781101
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3914101,679,800 - 101,846,717 (-)NCBI
GRCm3814101,442,364 - 101,609,281 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001074747 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518822 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518823 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518824 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518825 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518826 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518827 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518829 (Get FASTA)   NCBI Sequence Viewer  
  XP_006518830 (Get FASTA)   NCBI Sequence Viewer  
  XP_011243304 (Get FASTA)   NCBI Sequence Viewer  
  XP_017171424 (Get FASTA)   NCBI Sequence Viewer  
  XP_017171426 (Get FASTA)   NCBI Sequence Viewer  
  XP_017171427 (Get FASTA)   NCBI Sequence Viewer  
  XP_030103567 (Get FASTA)   NCBI Sequence Viewer  
  XP_036014422 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH42747 (Get FASTA)   NCBI Sequence Viewer  
  AAH64433 (Get FASTA)   NCBI Sequence Viewer  
  AAH80762 (Get FASTA)   NCBI Sequence Viewer  
  AAI17870 (Get FASTA)   NCBI Sequence Viewer  
  AAI17871 (Get FASTA)   NCBI Sequence Viewer  
  BAC27263 (Get FASTA)   NCBI Sequence Viewer  
  BAC30322 (Get FASTA)   NCBI Sequence Viewer  
  BAC32048 (Get FASTA)   NCBI Sequence Viewer  
  BAD90243 (Get FASTA)   NCBI Sequence Viewer  
  BAE42613 (Get FASTA)   NCBI Sequence Viewer  
  BAE43074 (Get FASTA)   NCBI Sequence Viewer  
  Q8BYJ6 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001074747   ⟸   NM_001081278
- UniProtKB: Q8BYJ6 (UniProtKB/Swiss-Prot),   E9Q6Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006518822   ⟸   XM_006518759
- Peptide Label: isoform X1
- UniProtKB: Q8BYJ6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006518824   ⟸   XM_006518761
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006518823   ⟸   XM_006518760
- Peptide Label: isoform X2
- UniProtKB: E0CX53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006518825   ⟸   XM_006518762
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006518826   ⟸   XM_006518763
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006518830   ⟸   XM_006518767
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_006518827   ⟸   XM_006518764
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006518829   ⟸   XM_006518766
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_011243304   ⟸   XM_011245002
- Peptide Label: isoform X11
- UniProtKB: Q8BYJ6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017171424   ⟸   XM_017315935
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017171426   ⟸   XM_017315937
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017171427   ⟸   XM_017315938
- Peptide Label: isoform X14
- Sequence:
RefSeq Acc Id: XP_030103567   ⟸   XM_030247707
- Peptide Label: isoform X10
RefSeq Acc Id: ENSMUSP00000124511   ⟸   ENSMUST00000159951
RefSeq Acc Id: ENSMUSP00000124734   ⟸   ENSMUST00000159664
RefSeq Acc Id: ENSMUSP00000097913   ⟸   ENSMUST00000100340
RefSeq Acc Id: ENSMUSP00000124909   ⟸   ENSMUST00000162617
RefSeq Acc Id: ENSMUSP00000125509   ⟸   ENSMUST00000161991
RefSeq Acc Id: XP_036014422   ⟸   XM_036158529
- Peptide Label: isoform X6
Protein Domains
PID   Rab-GAP TBC

Promoters
RGD ID:8683116
Promoter ID:EPDNEW_M19589
Type:multiple initiation site
Name:Tbc1d4_1
Description:Mus musculus TBC1 domain family, member 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19590  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3814101,463,215 - 101,463,275EPDNEW
RGD ID:8683118
Promoter ID:EPDNEW_M19590
Type:multiple initiation site
Name:Tbc1d4_2
Description:Mus musculus TBC1 domain family, member 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19589  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3814101,609,145 - 101,609,205EPDNEW
RGD ID:6825472
Promoter ID:MM_KWN:17651
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4
Transcripts:ENSMUST00000041648,   ENSMUST00000110795,   ENSMUST00000110796,   NM_001081278,   UC007UVM.1,   UC007UVO.1,   UC007UVP.1,   UC007UVQ.1,   UC007UVR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3614102,007,926 - 102,008,426 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2429660 AgrOrtholog
Ensembl Genes ENSMUSG00000033083 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000097913 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000124511 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000124734 UniProtKB/TrEMBL
  ENSMUSP00000124909 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000125509 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000100340 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000159664 UniProtKB/TrEMBL
  ENSMUST00000159951 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000161304 ENTREZGENE
  ENSMUST00000161991 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000162617 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DUF3350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab-GTPase-TBC_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:210789 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2429660 ENTREZGENE
NCBI Gene 210789 ENTREZGENE
Pfam DUF3350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RabGAP-TBC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tbc1d4 PhenoGen
PROSITE PID UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TBC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E0CX53 ENTREZGENE, UniProtKB/TrEMBL
  E9Q6Q8 ENTREZGENE, UniProtKB/TrEMBL
  F6S7E8_MOUSE UniProtKB/TrEMBL
  F6SUV7_MOUSE UniProtKB/TrEMBL
  H7BX82_MOUSE UniProtKB/TrEMBL
  Q05BK2_MOUSE UniProtKB/TrEMBL
  Q8BYJ6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q149C0 UniProtKB/Swiss-Prot
  Q149C1 UniProtKB/Swiss-Prot
  Q3T9E8 UniProtKB/Swiss-Prot
  Q3TAQ5 UniProtKB/Swiss-Prot
  Q5DU23 UniProtKB/Swiss-Prot
  Q66JU2 UniProtKB/Swiss-Prot
  Q6P2M2 UniProtKB/Swiss-Prot
  Q8BMH6 UniProtKB/Swiss-Prot
  Q8BXM2 UniProtKB/Swiss-Prot