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Gene: Sohlh1 (spermatogenesis and oogenesis specific basic helix-loop-helix 1) Mus musculus
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Symbol: Sohlh1
Name: spermatogenesis and oogenesis specific basic helix-loop-helix 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in gamete generation; ovarian follicle development; and positive regulation of transcription by RNA polymerase II. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in male infertility and ovarian dysgenesis 5. Is expressed in gonad and hindlimb long bone. Orthologous to human SOHLH1 (spermatogenesis and oogenesis specific basic helix-loop-helix 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; etoposide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gm110; helix-loop-helix protein NOHLH; Nohlh; RP23-123F7.2; spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl225,842,995 - 25,847,248 (-)Ensembl
GRCm38225,842,995 - 25,847,248 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37225,698,515 - 25,702,768 (-)NCBIGRCm37mm9NCBIm37
MGSCv36225,665,004 - 25,669,257 (-)NCBImm8
Celera225,562,491 - 25,566,744 (-)NCBICelera
Cytogenetic Map2 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sohlh1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1622972
Created: 2007-05-02
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.