Mdfic2 (MyoD family inhibitor domain containing 2)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| FTP Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Mdfic2 (MyoD family inhibitor domain containing 2) Mus musculus

Analyze

Symbol:

Mdfic2

Name:

MyoD family inhibitor domain containing 2

RGD ID:

1622832

MGI Page

MGI

Description:

Orthologous to human MDFIC2 (MyoD family inhibitor domain containing 2).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Gm765; hypothetical protein LOC330390; myoD family inhibitor domain-containing protein 2; uncharacterized protein LOC330390

RGD Orthologs

Human

Rat

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	98,212,665 - 98,319,715 (-)	NCBI	GRCm39		mm39
GRCm38	6	98,238,014 - 98,342,754 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	98,235,708 - 98,342,754 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	98,188,008 - 98,292,748 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	98,203,540 - 98,308,135 (-)	NCBI			mm8
Celera	6	100,098,354 - 100,203,386 (-)	NCBI		Celera
Cytogenetic Map	6	D3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Cellular Component

cellular_component (ND)

Molecular Function

molecular_function (ND)

References

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Mdfic2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	98,212,665 - 98,319,715 (-)	NCBI	GRCm39		mm39
GRCm38	6	98,238,014 - 98,342,754 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	98,235,708 - 98,342,754 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	98,188,008 - 98,292,748 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	98,203,540 - 98,308,135 (-)	NCBI			mm8
Celera	6	100,098,354 - 100,203,386 (-)	NCBI		Celera
Cytogenetic Map	6	D3	NCBI

MDFIC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	70,194,479 - 70,312,638 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	70,194,479 - 70,312,638 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	70,243,630 - 70,361,789 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	3	p13	NCBI
CHM1_1	3	70,194,911 - 70,313,069 (-)	NCBI		CHM1_1

Mdfic2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	130,845,260 - 130,948,054 (-)	NCBI
Rnor_6.0	4	130,649,564 - 130,751,397 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	195,031,931 - 195,246,182 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	132,858,542 - 133,083,891 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	4	119,718,570 - 119,821,412 (-)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

MDFIC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	71,497,457 - 71,612,601 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	71,497,457 - 71,611,948 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	70,133,229 - 70,251,520 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

MDFIC2
(Canis lupus familiaris - dog)

No map positions available.

Mdfic2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936603	2,042,355 - 2,052,291 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MDFIC2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	51,629,377 - 51,741,546 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	51,631,445 - 51,742,570 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	56,832,814 - 56,913,242 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MDFIC2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	31,193,837 - 31,304,898 (-)	NCBI

Mdfic2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624773	4,780,884 - 4,790,397 (-)	NCBI

Position Markers

D6Mit165

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	98,258,792 - 98,258,933	UniSTS	GRCm38
MGSCv37	6	98,208,786 - 98,208,927	UniSTS	GRCm37
Celera	6	100,119,231 - 100,119,372	UniSTS
Cytogenetic Map	6	D3	UniSTS
cM Map	6	42.0	UniSTS
Whitehead Genetic	6	33.9	UniSTS
Whitehead_YAC	6		UniSTS

D6Mit66

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	98,270,318 - 98,270,528	UniSTS	GRCm38
MGSCv37	6	98,220,312 - 98,220,522	UniSTS	GRCm37
Cytogenetic Map	6	D3	UniSTS
cM Map	6	41.0	UniSTS
Whitehead Genetic	6	33.9	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	1	117500000	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139100000	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45314059	128835032	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46935985	136423692	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48720000	125360000	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48720000	148450000	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48726556	125356785	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52161713	116155267	Mouse
1300650	Bw18_m	body weight QTL 18 (mouse)			Not determined		6	66713869	100714031	Mouse
1301876	Bits2_m	bitterness sensitivity 2 (mouse)			Not determined		6	70425898	104426034	Mouse
1301813	Skl3_m	skeletal size (tail length) 3 (mouse)			Not determined		6	70425898	104426034	Mouse
1301034	Egrm2_m	early growth rate (mouse)			Not determined		6	70425898	104426034	Mouse
1300869	Stheal5_m	soft tissue heal 5 (mouse)			Not determined		6	71575060	105575178	Mouse
1300954	Fcsa1_m	femoral cross-sectional area 1 (mouse)			Not determined		6	71981024	105981170	Mouse
1301521	Pas1c_m	pulmonary adenoma susceptibility 1c (mouse)			Not determined		6	71981024	105981170	Mouse
13506930	Recrq9_m	recombination rate in male meiosis QTL 9 (mouse)					6	73500000	134700000	Mouse
1301320	Ots1_m	ovarian teratoma susceptibility 1 (mouse)			Not determined		6	75447583	104503555	Mouse
10043901	Pfat5_m	predicted fat percentage 5 (mouse)			Not determined		6	75607306	109607450	Mouse
10412208	Cypr4_m	cytokine production 4 (mouse)			Not determined		6	75716503	109716697	Mouse
1357875	Pfat2_m	predicted fat percentage 2 (mouse)			Not determined		6	76463949	110464093	Mouse
4141376	Dbm1_m	diabetes modifier 1 (mouse)			Not determined		6	78629504	121115387	Mouse
14696731	Pairq1_m	P. aeruginosa infection resistance QTL 1 (mouse)					6	81500000	102200000	Mouse
10043864	T2dm4sa_m	type 2 diabetes mellitus 4 in SMXA RI mice (mouse)			Not determined		6	83713869	147052561	Mouse
11251720	Ewc4_m	ethanol withdrawal and consumption 4 (mouse)					6	84122513	118122513	Mouse
1301687	Mnic2_m	macronutrient intake (mouse)			Not determined		6	86806805	113544602	Mouse
1301744	Hdlq11_m	HDL QTL 11 (mouse)			Not determined		6	87503360	121503555	Mouse
1301262	Gasa3_m	gastritis type A susceptibility locus 3 (mouse)			Not determined		6	89005405	123005603	Mouse
1301244	Ichs_m	immediate cutaneous hypersensitivity QTL (mouse)			Not determined		6	90795610	124795846	Mouse
11532719	Sluc45_m	susceptibility to lung cancer 45 (mouse)					6	92607306	98258933	Mouse
4141578	Obrq1_m	obesity resistance QTL 1 (mouse)			Not determined			92607306	112004738	Mouse
11353842	Bmiq4_m	body mass index QTL 4 (mouse)					6	92607306	146429238	Mouse
1301292	Cfbw2_m	cystic fibrosis body weight 2 (mouse)			Not determined		6	95004651	129004738	Mouse
1300704	Cia3_m	collagen induced arthritis QTL 3 (mouse)			Not determined		6	96347325	130347522	Mouse
11040599	Lmr4b_m	leishmaniasis resistance 4b (mouse)					6	96347325	130347522	Mouse
4141940	W6q5_m	weight 6 weeks QTL 5 (mouse)			Not determined			96655951	146633626	Mouse
4142416	Egq11_m	early growth QTL 11 (mouse)			Not determined			96655951	146633626	Mouse
1357555	Tesq2_m	testis weight QTL 2 (mouse)			Not determined		6	96655951	146633626	Mouse
10043923	Bhr7_m	bronchial hyperresponsiveness 7 (mouse)			Not determined		6	98242853	132242977	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	129
Count of miRNA genes:	127
Interacting mature miRNAs:	129
Transcripts:	ENSMUST00000164491
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001128092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_036166250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC112682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC125077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC147266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC147267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000164491 ⟹ ENSMUSP00000127120

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	98,235,708 - 98,342,754 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000204914

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	98,341,463 - 98,342,659 (-)	Ensembl

RefSeq Acc Id:

NM_001128092 ⟹ NP_001121564

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	98,214,975 - 98,319,715 (-)	NCBI
GRCm38	6	98,238,014 - 98,342,754 (-)	ENTREZGENE
MGSCv37	6	98,188,008 - 98,292,748 (-)	RGD
Celera	6	100,098,354 - 100,203,386 (-)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

CGCAAGTTGGATGCTTCTGGCAGCCACACAAATCTAGCACCACCCAGGGAGGGAGTGTGTTTGC
CTCTCTGCTCACTTCTGCCAGAGTGGAGGAATGCTGGACACCCAGAGACAAGGGAGGCTGCCGC
GCACCACAGCCCAGGCCCACACCTCTGGCTTCCTCCTTTAGAGACACACAGATGTCAGAAATTG
AGTTGGAAAAGATAAAAGTAAGAACAGCCGAGCATTTTGAAAATGGCAAAAATAACCTTCCTTG
GTTAAAAGAAGATACGCAACTCACGAATGAAAAGCATGCAGACGAGAAACCTATTAATGCTATC
GTAATAAATTCAGTATCCGAATTCAGTATCACAGATGGACCAGCCCAGGAAACCCCCAATGAGA
AAAACCTGTCAGGATCGAGCACTTCACTCTCTTCCCTTGAAGAATGCCAAACGAAATTTCCCTA
CCTCCAAACTAATACTTCAGTTCATCGGAGAGATGCTGATGAGGAGTGTGCCTCCCTAGTCCTC
ACCTGTCTCTTCTGCCAGTTCTTGGACTGCCTCTTCATGCTCCCTGACACGTGTGAGACAGTGT
GCATCAACCTGTGCTGCCCCTCTCACAGGTACTACTCTGCCTCCGATGAGAACCATCCACACAA
TGACTGCAACTTGACCTGCGATGTGGACTGTAGTCTCTTTGAATCCTGCCATGAGACCAGTGAA
TGCCTGGAGCTGGCCATGGAGATATCAGAAATCTGTTACCGATAGTGCCAGAAAGGATTAGCAC
TCAGGCGGTCCTTAGAGTGCATCTGAGATAAAGAGCTCTCTCTGTGTGCCCAAATGCA

hide sequence

RefSeq Acc Id:

XM_036166250 ⟹ XP_036022143

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	98,212,665 - 98,228,032 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001121564	(Get FASTA)	NCBI Sequence Viewer
	XP_036022143	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI47267	(Get FASTA)	NCBI Sequence Viewer
	AAI47268	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001121564 ⟸ NM_001128092
- UniProtKB:	B2RVL9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSEIELEKIKVRTAEHFENGKNNLPWLKEDTQLTNEKHADEKPINAIVINSVSEFSITDGPAQE TPNEKNLSGSSTSLSSLEECQTKFPYLQTNTSVHRRDADEECASLVLTCLFCQFLDCLFMLPDT CETVCINLCCPSHRYYSASDENHPHNDCNLTCDVDCSLFESCHETSECLELAMEISEICYR hide sequence

RefSeq Acc Id:

ENSMUSP00000127120 ⟸ ENSMUST00000164491

RefSeq Acc Id:	XP_036022143 ⟸ XM_036166250
- Peptide Label:	isoform X1

Promoters

RGD ID:

6890628

Promoter ID:

EPDNEW_M8716

Type:

initiation region

Name:

Gm765_1

Description:

Mus musculus predicted gene 765 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	98,342,671 - 98,342,731	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2685611	AgrOrtholog
Ensembl Genes	ENSMUSG00000090667	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000127120	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000164491	ENTREZGENE, UniProtKB/TrEMBL
InterPro	MDFI/MDFIC	UniProtKB/TrEMBL
KEGG Report	mmu:330390	UniProtKB/TrEMBL
MGD	MGI:2685611	ENTREZGENE
NCBI Gene	330390	ENTREZGENE
PANTHER	PTHR15304	UniProtKB/TrEMBL
Pfam	MDFI	UniProtKB/TrEMBL
PhenoGen	Mdfic2	PhenoGen
UniProt	B2RVL9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-10-19	Mdfic2	MyoD family inhibitor domain containing 2	Gm765	predicted gene 765	Symbol and/or name updated	27372883	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)