Msantd1 (Myb/SANT-like DNA-binding domain containing 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Msantd1 (Myb/SANT-like DNA-binding domain containing 1) Mus musculus
Analyze
Symbol: Msantd1
Name: Myb/SANT-like DNA-binding domain containing 1
RGD ID: 1622775
MGI Page MGI
Description: Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be active in nuclear body. Is expressed in ductus deferens; epididymis; esophagus; and testis. Orthologous to human MSANTD1 (Myb/SANT DNA binding domain containing 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A930005I04Rik; Gm144; hypothetical protein LOC403174; myb/SANT-like DNA-binding domain-containing protein 1; uncharacterized protein C4orf44 homolog; uncharacterized protein MSANTD1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39535,071,581 - 35,084,333 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl535,065,356 - 35,081,183 (+)EnsemblGRCm39 Ensembl
GRCm38534,914,593 - 34,926,989 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,908,012 - 34,923,839 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,258,564 - 35,266,488 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,232,772 - 35,240,696 (+)NCBIMGSCv36mm8
Celera532,389,812 - 32,397,737 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nuclear body  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635  
PMID:24194600   PMID:27626380   PMID:38355793  


Genomics

Comparative Map Data
Msantd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39535,071,581 - 35,084,333 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl535,065,356 - 35,081,183 (+)EnsemblGRCm39 Ensembl
GRCm38534,914,593 - 34,926,989 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,908,012 - 34,923,839 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,258,564 - 35,266,488 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,232,772 - 35,240,696 (+)NCBIMGSCv36mm8
Celera532,389,812 - 32,397,737 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.94NCBI
MSANTD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3843,244,273 - 3,256,613 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl43,244,369 - 3,271,738 (+)EnsemblGRCh38hg38GRCh38
GRCh3743,246,096 - 3,258,340 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3643,220,565 - 3,235,638 (+)NCBINCBI36Build 36hg18NCBI36
Celera43,162,291 - 3,169,866 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef43,189,248 - 3,196,823 (+)NCBIHuRef
CHM1_143,248,522 - 3,256,097 (+)NCBICHM1_1
T2T-CHM13v2.043,243,031 - 3,255,371 (+)NCBIT2T-CHM13v2.0
Msantd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81480,059,985 - 80,070,336 (-)NCBIGRCr8
mRatBN7.21475,832,368 - 75,845,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,835,380 - 75,844,183 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1480,288,354 - 80,294,546 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01481,529,009 - 81,535,201 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01477,974,245 - 77,980,437 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01481,091,675 - 81,105,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1481,090,858 - 81,100,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,780,150 - 81,793,570 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,476,972 - 81,483,164 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1474,761,454 - 74,767,646 (-)NCBICelera
Cytogenetic Map14q21NCBI
Msantd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555142,037,891 - 2,053,746 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555142,037,891 - 2,053,746 (+)NCBIChiLan1.0ChiLan1.0
MSANTD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v233,587,575 - 3,615,269 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan143,520,980 - 3,548,660 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v043,393,646 - 3,408,820 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.143,292,754 - 3,307,786 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl43,290,354 - 3,305,139 (+)Ensemblpanpan1.1panPan2
MSANTD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1361,058,993 - 61,076,816 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl361,064,335 - 61,075,072 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha363,642,759 - 63,665,797 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0361,534,630 - 61,557,671 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl361,536,790 - 61,550,600 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1361,026,239 - 61,049,273 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0361,230,547 - 61,253,592 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0361,596,177 - 61,613,334 (-)NCBIUU_Cfam_GSD_1.0
Msantd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528566,730,271 - 66,741,262 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647720,431,861 - 20,440,848 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647720,431,866 - 20,438,330 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSANTD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl81,938,397 - 1,947,985 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.181,934,960 - 1,944,754 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.281,590,769 - 1,596,940 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MSANTD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12745,480,897 - 45,490,192 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2745,480,545 - 45,491,188 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660511,839,654 - 1,852,085 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Msantd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475524,590,334 - 24,597,869 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475524,590,378 - 24,602,806 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Msantd1
349 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:143
Count of miRNA genes:129
Interacting mature miRNAs:135
Transcripts:ENSMUST00000050535
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53102427565024480Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53348866767488876Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53102427565024480Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53157045865570458Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse

Markers in Region
D5Jcs85  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38534,922,747 - 34,922,904UniSTSGRCm38
MGSCv37535,265,396 - 35,265,553UniSTSGRCm37
Celera532,396,645 - 32,396,802UniSTS
Cytogenetic Map5B2UniSTS
cM Map5 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000050535   ⟹   ENSMUSP00000057362
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl535,073,259 - 35,081,183 (+)Ensembl
GRCm38.p6 Ensembl534,915,915 - 34,923,839 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201636
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl535,065,356 - 35,075,160 (+)Ensembl
GRCm38.p6 Ensembl534,908,012 - 34,917,816 (+)Ensembl
Ensembl Acc Id: ENSMUST00000202205   ⟹   ENSMUSP00000144008
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl535,074,883 - 35,081,034 (+)Ensembl
GRCm38.p6 Ensembl534,917,539 - 34,923,690 (+)Ensembl
Ensembl Acc Id: ENSMUST00000212362   ⟹   ENSMUSP00000148522
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl535,072,432 - 35,080,908 (+)Ensembl
GRCm38.p6 Ensembl534,915,088 - 34,923,564 (+)Ensembl
RefSeq Acc Id: NM_001310550   ⟹   NP_001297479
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39535,073,259 - 35,081,183 (+)NCBI
GRCm38534,915,915 - 34,923,839 (+)NCBI
Sequence:
RefSeq Acc Id: NM_207277   ⟹   NP_997160
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39535,073,259 - 35,081,183 (+)NCBI
GRCm38534,915,915 - 34,923,839 (+)NCBI
MGSCv37535,258,564 - 35,266,488 (+)RGD
Celera532,389,812 - 32,397,737 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006504012   ⟹   XP_006504075
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39535,071,937 - 35,084,333 (+)NCBI
GRCm38534,914,593 - 34,926,989 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011240753   ⟹   XP_011239055
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39535,071,937 - 35,084,333 (+)NCBI
GRCm38534,914,593 - 34,926,989 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017320960   ⟹   XP_017176449
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39535,071,937 - 35,084,333 (+)NCBI
GRCm38534,914,593 - 34,926,989 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036165260   ⟹   XP_036021153
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39535,071,581 - 35,084,333 (+)NCBI
Sequence:
RefSeq Acc Id: NP_997160   ⟸   NM_207277
- Peptide Label: isoform 1
- UniProtKB: Q8BIL2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006504075   ⟸   XM_006504012
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011239055   ⟸   XM_011240753
- Peptide Label: isoform X1
- UniProtKB: A0A1D5RLV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017176449   ⟸   XM_017320960
- Peptide Label: isoform X3
- UniProtKB: A0A0J9YU52 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001297479   ⟸   NM_001310550
- Peptide Label: isoform 2
- UniProtKB: A0A0J9YU52 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000144008   ⟸   ENSMUST00000202205
Ensembl Acc Id: ENSMUSP00000148522   ⟸   ENSMUST00000212362
Ensembl Acc Id: ENSMUSP00000057362   ⟸   ENSMUST00000050535
RefSeq Acc Id: XP_036021153   ⟸   XM_036165260
- Peptide Label: isoform X4
Protein Domains
Myb-like   Myb/SANT-like DNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BIL2-F1-model_v2 AlphaFold Q8BIL2 1-278 view protein structure

Promoters
RGD ID:6836824
Promoter ID:MM_KWN:41987
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   MEF_B6
Transcripts:NM_207277
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36535,257,781 - 35,260,392 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2684990 AgrOrtholog
Ensembl Genes ENSMUSG00000051246 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000050535 ENTREZGENE
  ENSMUST00000050535.2 UniProtKB/Swiss-Prot
  ENSMUST00000202205 ENTREZGENE
  ENSMUST00000202205.2 UniProtKB/TrEMBL
  ENSMUST00000212362 ENTREZGENE
  ENSMUST00000212362.2 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Myb/SANT-like_DNA-bd_dom_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myb_DNA-bind_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:403174 UniProtKB/Swiss-Prot
MGD MGI:2684990 ENTREZGENE
NCBI Gene 403174 ENTREZGENE
PANTHER MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22666 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Myb_DNA-bind_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Msantd1 PhenoGen
UniProt A0A0J9YU52 ENTREZGENE, UniProtKB/TrEMBL
  A0A1D5RLV8 ENTREZGENE, UniProtKB/TrEMBL
  MSD1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-27 Msantd1  Myb/SANT-like DNA-binding domain containing 1  A930005I04Rik  RIKEN cDNA A930005I04 gene  Symbol and/or name change 5135510 APPROVED