Mtres1 (mitochondrial transcription rescue factor 1) - Rat Genome Database

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Gene: Mtres1 (mitochondrial transcription rescue factor 1) Mus musculus
Analyze
Symbol: Mtres1
Name: mitochondrial transcription rescue factor 1
RGD ID: 1622312
MGI Page MGI
Description: Predicted to enable ribosomal large subunit binding activity and tRNA binding activity. Predicted to be involved in regulation of mitochondrial transcription and rescue of stalled ribosome. Located in mitochondrion. Orthologous to human MTRES1 (mitochondrial transcription rescue factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700021F05Rik; hypothetical protein LOC67851; RIKEN cDNA 1700021F05 gene; uncharacterized protein C6orf203 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391043,401,115 - 43,417,037 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1043,401,129 - 43,416,990 (-)EnsemblGRCm39 Ensembl
GRCm381043,525,119 - 43,541,041 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1043,525,133 - 43,540,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv371043,244,927 - 43,260,800 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361043,213,536 - 43,229,409 (-)NCBIMGSCv36mm8
Celera1044,391,825 - 44,407,796 (-)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11707072   PMID:11752298   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14610273  
PMID:15489334   PMID:16141072   PMID:16141073   PMID:18614015   PMID:18799693   PMID:21873635   PMID:31162944   PMID:32325033  


Genomics

Comparative Map Data
Mtres1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391043,401,115 - 43,417,037 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1043,401,129 - 43,416,990 (-)EnsemblGRCm39 Ensembl
GRCm381043,525,119 - 43,541,041 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1043,525,133 - 43,540,994 (-)EnsemblGRCm38mm10GRCm38
MGSCv371043,244,927 - 43,260,800 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361043,213,536 - 43,229,409 (-)NCBIMGSCv36mm8
Celera1044,391,825 - 44,407,796 (-)NCBICelera
Cytogenetic Map10B2NCBI
cM Map1023.01NCBI
MTRES1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386107,028,199 - 107,051,586 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6107,028,199 - 107,051,586 (+)EnsemblGRCh38hg38GRCh38
GRCh376107,349,403 - 107,372,790 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366107,456,110 - 107,479,238 (+)NCBINCBI36Build 36hg18NCBI36
Build 346107,456,109 - 107,479,238NCBI
Celera6108,097,763 - 108,120,882 (+)NCBICelera
Cytogenetic Map6q21NCBI
HuRef6104,921,421 - 104,943,891 (+)NCBIHuRef
CHM1_16107,612,048 - 107,635,159 (+)NCBICHM1_1
T2T-CHM13v2.06108,207,085 - 108,230,443 (+)NCBIT2T-CHM13v2.0
Mtres1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82048,604,479 - 48,622,364 (-)NCBIGRCr8
mRatBN7.22047,022,343 - 47,038,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2047,022,342 - 47,038,805 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2048,736,829 - 48,753,174 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02048,386,835 - 48,403,008 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02049,071,634 - 49,088,055 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02048,276,101 - 48,294,975 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2048,275,762 - 48,294,948 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02049,934,857 - 49,950,906 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2052,949,435 - 52,966,218 (+)NCBICelera
Cytogenetic Map20q13NCBI
Mtres1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541132,318,079 - 32,341,989 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541132,318,079 - 32,338,597 (+)NCBIChiLan1.0ChiLan1.0
MTRES1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25127,044,353 - 127,068,253 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16124,931,922 - 124,955,569 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06104,839,280 - 104,862,854 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16108,709,555 - 108,729,976 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6108,709,803 - 108,729,976 (+)Ensemblpanpan1.1panPan2
MTRES1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11264,278,569 - 64,293,999 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1264,244,529 - 64,303,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1264,065,280 - 64,080,933 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01265,122,203 - 65,137,957 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1265,122,128 - 65,147,799 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11264,482,216 - 64,497,961 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01264,326,248 - 64,341,811 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01264,599,931 - 64,615,890 (+)NCBIUU_Cfam_GSD_1.0
Mtres1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494699,192,327 - 99,207,645 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365643,467,192 - 3,482,720 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365643,467,223 - 3,482,507 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTRES1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl173,162,364 - 73,180,017 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1173,162,330 - 73,174,266 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MTRES1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11366,798,141 - 66,818,964 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1366,798,134 - 66,807,567 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604039,125,651 - 39,146,174 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtres1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478015,233,566 - 15,246,178 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478015,233,686 - 15,246,172 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mtres1
711 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:729
Count of miRNA genes:407
Interacting mature miRNAs:469
Transcripts:ENSMUST00000019932, ENSMUST00000126463, ENSMUST00000147196, ENSMUST00000152926
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208561Wght8_mweight 8 (mouse)10495000043875996Mouse
1302092Ath11_matherosclerosis 11 (mouse)Not determined10615194558693521Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
1301448Pas11_mpulmonary adenoma susceptibility 11 (mouse)Not determined10989026443890391Mouse
1301129Alcp15_malcohol preference locus 15 (mouse)Not determined10989026443890391Mouse
1302133Alcp16_malcohol preference locus 16 (mouse)Not determined10989026443890391Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
10755518Chol16_mcholesterol 16 (mouse)101891504352915043Mouse
1302160Mbis2_mMycobacterium bovis-induced systemic lupus erythematosus 2 (mouse)Not determined102028318556031223Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
1301003Lmblgq4_mlimb length QTL 4 (mouse)Not determined102159119268091639Mouse
26884394Humsd3_mhumerus midshaft diameter 3, 10 week (mouse)102237589951076096Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
4142209Psrs1_mpsoriasis susceptibility 1 (mouse)Not determined102689026446720483Mouse
1300898Cfid_mcystic fibrosis intestinal distress (mouse)Not determined102972040363720483Mouse
10045632Heal16_mwound healing/regeneration 16 (mouse)Not determined103097449964974630Mouse
1357558Bmch4_mbone mechanical trait 4 (mouse)Not determined103157713665577284Mouse
27095920Pglq9_mpelvic girdle length QTL 9, 10 week (mouse)103377599670835830Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
21079434Bdym5_mbody mass QTL 5 (mouse)104054599654836096Mouse
4141070Ltgq1_mliver triglyceride QTL 1 (mouse)Not determined4123732675237326Mouse

Markers in Region
STS-Z40857  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381043,530,539 - 43,530,736UniSTSGRCm38
GRCm3810120,771,433 - 120,772,151UniSTSGRCm38
MGSCv371043,250,345 - 43,250,542UniSTSGRCm37
MGSCv3710120,208,489 - 120,209,207UniSTSGRCm37
Celera1044,397,244 - 44,397,441UniSTS
Celera10123,137,075 - 123,137,793UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map10B2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006512833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006512834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017314069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC163661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK006199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV045344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000126463
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1043,409,150 - 43,416,990 (-)Ensembl
GRCm38.p6 Ensembl1043,533,154 - 43,540,994 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147196   ⟹   ENSMUSP00000119053
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1043,401,129 - 43,416,964 (-)Ensembl
GRCm38.p6 Ensembl1043,525,133 - 43,540,968 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152926
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1043,401,155 - 43,401,839 (-)Ensembl
GRCm38.p6 Ensembl1043,525,159 - 43,525,843 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214198
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1043,414,121 - 43,416,962 (-)Ensembl
GRCm38.p6 Ensembl1043,538,125 - 43,540,966 (-)Ensembl
RefSeq Acc Id: NM_026411   ⟹   NP_080687
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391043,401,115 - 43,417,014 (-)NCBI
GRCm381043,525,119 - 43,541,018 (-)NCBI
MGSCv371043,244,927 - 43,260,800 (-)RGD
Celera1044,391,825 - 44,407,796 (-)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512833   ⟹   XP_006512896
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391043,401,129 - 43,417,011 (-)NCBI
GRCm381043,525,133 - 43,541,019 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006512834   ⟹   XP_006512897
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391043,401,129 - 43,416,993 (-)NCBI
GRCm381043,525,133 - 43,540,979 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243202   ⟹   XP_011241504
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391043,401,208 - 43,417,037 (-)NCBI
GRCm381043,525,629 - 43,541,041 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017314069   ⟹   XP_017169558
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391043,401,129 - 43,410,070 (-)NCBI
GRCm381043,525,133 - 43,534,074 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936264
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391043,401,208 - 43,417,037 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_080687   ⟸   NM_026411
- UniProtKB: Q3TQU4 (UniProtKB/Swiss-Prot),   Q9CQF4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512896   ⟸   XM_006512833
- Peptide Label: isoform X1
- UniProtKB: Q3TQU4 (UniProtKB/Swiss-Prot),   Q9CQF4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512897   ⟸   XM_006512834
- Peptide Label: isoform X1
- UniProtKB: Q3TQU4 (UniProtKB/Swiss-Prot),   Q9CQF4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011241504   ⟸   XM_011243202
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017169558   ⟸   XM_017314069
- Peptide Label: isoform X1
- UniProtKB: Q3TQU4 (UniProtKB/Swiss-Prot),   Q9CQF4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000119053   ⟸   ENSMUST00000147196
Protein Domains
S4 RNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CQF4-F1-model_v2 AlphaFold Q9CQF4 1-240 view protein structure

Promoters
RGD ID:6818756
Promoter ID:MM_KWN:4042
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_026411,   OTTMUST00000081051,   OTTMUST00000081063
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361043,260,389 - 43,260,889 (-)MPROMDB
RGD ID:8671914
Promoter ID:EPDNEW_M13988
Type:initiation region
Name:1700021F05Rik_1
Description:Mus musculus RIKEN cDNA 1700021F05 gene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381043,540,961 - 43,541,021EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915101 AgrOrtholog
Ensembl Genes ENSMUSG00000019797 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000147196 ENTREZGENE
  ENSMUST00000147196.3 UniProtKB/Swiss-Prot
KEGG Report mmu:67851 UniProtKB/Swiss-Prot
MGD MGI:1915101 ENTREZGENE
NCBI Gene 67851 ENTREZGENE
PANTHER MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 UniProtKB/Swiss-Prot
  PTHR13633 UniProtKB/Swiss-Prot
PhenoGen Mtres1 PhenoGen
UniProt CF203_MOUSE UniProtKB/Swiss-Prot
  Q3TQU4 ENTREZGENE
  Q9CQF4 ENTREZGENE
UniProt Secondary Q3TQU4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-27 Mtres1  mitochondrial transcription rescue factor 1  1700021F05Rik  RIKEN cDNA 1700021F05 gene  Symbol and/or name change 5135510 APPROVED