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Gene: Mpc2 (mitochondrial pyruvate carrier 2) Mus musculus
Symbol: Mpc2
Name: mitochondrial pyruvate carrier 2
RGD ID: 1622287
Description: Contributes to pyruvate transmembrane transporter activity. Involved in mitochondrial acetyl-CoA biosynthetic process from pyruvate; mitochondrial pyruvate transmembrane transport; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Localizes to mitochondrion. Is expressed in embryo. Orthologous to human MPC2 (mitochondrial pyruvate carrier 2); INTERACTS WITH (+)-dexrazoxane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610006C01Rik; 2010002I07Rik; 2610205H19Rik; AA108335; brain protein 44; Brp; Brp44; ESTM4; ESTM43
Homo sapiens (human) : MPC2 (mitochondrial pyruvate carrier 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mpc2 (mitochondrial pyruvate carrier 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpc2 (mitochondrial pyruvate carrier 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MPC2 (mitochondrial pyruvate carrier 2)
Canis lupus familiaris (dog) : MPC2 (mitochondrial pyruvate carrier 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpc2 (mitochondrial pyruvate carrier 2)
Sus scrofa (pig) : MPC2 (mitochondrial pyruvate carrier 2)
Chlorocebus sabaeus (African green monkey) : MPC2 (mitochondrial pyruvate carrier 2)
Heterocephalus glaber (naked mole-rat) : Mpc2 (mitochondrial pyruvate carrier 2)
more info ...
Related Pseudogenes: Gm3982  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391165,288,829 - 165,308,787 (+)NCBI
GRCm381165,461,260 - 165,481,218 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,460,637 - 165,481,214 (+)EnsemblGRCm38mm10GRCm38
MGSCv371167,391,339 - 167,411,345 (+)NCBIGRCm37mm9NCBIm37
MGSCv361167,297,883 - 167,317,889 (+)NCBImm8
Celera1167,907,338 - 167,927,350 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mpc2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1622287
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.