Spag17 (sperm associated antigen 17) - Rat Genome Database

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Gene: Spag17 (sperm associated antigen 17) Mus musculus
Analyze
Symbol: Spag17
Name: sperm associated antigen 17
RGD ID: 1622249
MGI Page MGI
Description: Acts upstream of or within axonemal central apparatus assembly and epithelial cilium movement involved in extracellular fluid movement. Located in axonemal central apparatus. Is expressed in several structures, including alimentary system; genitourinary system; nasal cavity respiratory epithelium; respiratory system; and spinal cord. Human ortholog(s) of this gene implicated in spermatogenic failure. Orthologous to human SPAG17 (sperm associated antigen 17); INTERACTS WITH carbon nanotube; lead diacetate; titanium dioxide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4931427F14Rik; PF; PF6; projection protein PF6 homolog; Spag17-ps; sperm associated antigen 17, pseudogene; sperm-associated antigen 17
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39399,792,653 - 100,050,638 (+)NCBIGRCm39mm39
GRCm39 Ensembl399,792,722 - 100,050,638 (+)Ensembl
GRCm38399,885,417 - 100,143,322 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl399,885,406 - 100,143,322 (+)EnsemblGRCm38mm10GRCm38
MGSCv37399,689,340 - 99,947,245 (+)NCBIGRCm37mm9NCBIm37
MGSCv363100,014,493 - 100,271,849 (+)NCBImm8
Celera3102,093,645 - 102,348,668 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:15827353   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635   PMID:23418344   PMID:24194600  
PMID:25921334   PMID:26017218   PMID:27914912   PMID:29690537   PMID:32325033   PMID:32554934   PMID:32988999  


Genomics

Comparative Map Data
Spag17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39399,792,653 - 100,050,638 (+)NCBIGRCm39mm39
GRCm39 Ensembl399,792,722 - 100,050,638 (+)Ensembl
GRCm38399,885,417 - 100,143,322 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl399,885,406 - 100,143,322 (+)EnsemblGRCm38mm10GRCm38
MGSCv37399,689,340 - 99,947,245 (+)NCBIGRCm37mm9NCBIm37
MGSCv363100,014,493 - 100,271,849 (+)NCBImm8
Celera3102,093,645 - 102,348,668 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
SPAG17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1117,953,590 - 118,185,228 (-)EnsemblGRCh38hg38GRCh38
GRCh381117,953,590 - 118,185,228 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371118,496,213 - 118,727,851 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361118,297,811 - 118,529,357 (-)NCBINCBI36hg18NCBI36
Celera1116,723,952 - 116,955,535 (-)NCBI
Cytogenetic Map1p12NCBI
HuRef1116,352,708 - 116,584,124 (-)NCBIHuRef
CHM1_11118,611,575 - 118,843,130 (-)NCBICHM1_1
Spag17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22187,264,004 - 187,511,061 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2187,264,009 - 187,510,501 (+)Ensembl
Rnor_6.02202,159,659 - 202,452,361 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2202,200,797 - 202,443,026 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02221,837,514 - 221,849,735 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02221,858,583 - 221,903,718 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02221,623,554 - 221,784,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42194,845,206 - 195,089,225 (+)NCBIRGSC3.4rn4RGSC3.4
Celera2179,716,884 - 179,959,180 (+)NCBICelera
Cytogenetic Map2q34NCBI
Spag17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543521,078,646 - 21,282,043 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543521,063,005 - 21,281,997 (-)NCBIChiLan1.0ChiLan1.0
SPAG17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11119,335,369 - 119,556,711 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0184,339,906 - 84,571,723 (+)NCBIMhudiblu_PPA_v0panPan3
SPAG17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11755,248,136 - 55,468,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1755,248,137 - 55,467,902 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1754,891,599 - 55,114,823 (-)NCBI
ROS_Cfam_1.01756,127,507 - 56,346,757 (-)NCBI
UMICH_Zoey_3.11755,161,427 - 55,381,719 (-)NCBI
UNSW_CanFamBas_1.01755,199,577 - 55,419,614 (-)NCBI
UU_Cfam_GSD_1.01755,774,338 - 56,001,496 (-)NCBI
Spag17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505811,287,645 - 11,496,064 (+)NCBI
SpeTri2.0NW_0049366273,002,893 - 3,201,294 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPAG17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.14102,596,465 - 102,826,213 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24112,361,404 - 112,451,393 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPAG17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12015,545,340 - 15,780,126 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2015,579,532 - 15,767,354 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603818,210,829 - 18,453,389 (+)NCBIVero_WHO_p1.0
Spag17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477213,626,247 - 13,836,442 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AW546279  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383100,138,258 - 100,138,357UniSTSGRCm38
MGSCv37399,942,181 - 99,942,280UniSTSGRCm37
Celera3102,343,489 - 102,343,588UniSTS
Cytogenetic Map3F2.2UniSTS
Whitehead/MRC_RH3936.37UniSTS
UniSTS:224919  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383100,058,287 - 100,058,474UniSTSGRCm38
MGSCv37399,862,210 - 99,862,397UniSTSGRCm37
Celera3102,268,345 - 102,268,532UniSTS
Cytogenetic Map3F2.2UniSTS
PMC314463P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383100,058,283 - 100,058,522UniSTSGRCm38
MGSCv37399,862,206 - 99,862,445UniSTSGRCm37
Celera3102,268,341 - 102,268,580UniSTS
Cytogenetic Map3F2.2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316000000109800000Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316450000130370000Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328900000119100000Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330013439147599053Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337120713143647422Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)341000000116000000Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)344000000101700000Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)352000000102400000Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352300000137500000Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356796681100556821Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366139351100139488Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)368000000128600000Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369661247103661247Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369718176100747974Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370301597104301735Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372232660106232787Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372232660106232787Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375555995109556242Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379641414113641521Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381177336115177481Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382239727116239868Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383556675117556821Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383556675117556821Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383556675117556821Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383556675117556821Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383556675117556821Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383556675117556821Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383556675117556821Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383975596117975728Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384981602118981751Mouse
14746984Manh54_mmandible shape 54 (mouse)385381836119381836Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387301597125522587Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387320699121320699Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389232660137747247Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390469620124469756Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390470701124470701Mouse
1301398Rapop3_mradiation-induced apoptosis 3 (mouse)Not determined390603910100556821Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391092789125101432Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392344217126344334Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396700000148100000Mouse
1301277nctm1_mNakano cataract modifier 1 (mouse)Not determined397791322100465744Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398830392132830548Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398841635132841734Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398841635132841734Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined399130456133130601Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:801
Count of miRNA genes:531
Interacting mature miRNAs:600
Transcripts:ENSMUST00000127518, ENSMUST00000143050, ENSMUST00000152586, ENSMUST00000164539
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000127518
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl399,792,722 - 99,867,437 (+)Ensembl
GRCm38.p6 Ensembl399,885,406 - 99,960,121 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143050
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl399,934,924 - 99,946,267 (+)Ensembl
GRCm38.p6 Ensembl3100,027,608 - 100,038,951 (+)Ensembl
RefSeq Acc Id: ENSMUST00000152586
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl399,929,886 - 99,934,980 (+)Ensembl
GRCm38.p6 Ensembl3100,022,570 - 100,027,664 (+)Ensembl
RefSeq Acc Id: ENSMUST00000164539   ⟹   ENSMUSP00000134066
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl399,792,733 - 100,050,638 (+)Ensembl
GRCm38.p6 Ensembl399,885,417 - 100,143,322 (+)Ensembl
RefSeq Acc Id: NM_028892   ⟹   NP_083168
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39399,792,733 - 100,050,638 (+)NCBI
GRCm38399,885,417 - 100,143,322 (+)ENTREZGENE
MGSCv37399,689,340 - 99,947,245 (+)RGD
Celera3102,093,645 - 102,348,668 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036163362   ⟹   XP_036019255
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39399,792,653 - 100,049,986 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_083168   ⟸   NM_028892
- UniProtKB: Q5S003 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000134066   ⟸   ENSMUST00000164539
RefSeq Acc Id: XP_036019255   ⟸   XM_036163362
- Peptide Label: isoform X1

Promoters
RGD ID:6881792
Promoter ID:EPDNEW_M4347
Type:initiation region
Name:Spag17_1
Description:Mus musculus sperm associated antigen 17 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38399,885,432 - 99,885,492EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921612 AgrOrtholog
Ensembl Genes ENSMUSG00000027867 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000134066 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000164539 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro SPAG17 UniProtKB/Swiss-Prot
KEGG Report mmu:74362 UniProtKB/Swiss-Prot
MGD MGI:1921612 ENTREZGENE
NCBI Gene 74362 ENTREZGENE
PANTHER PTHR21963 UniProtKB/Swiss-Prot
PhenoGen Spag17 PhenoGen
UniProt Q5S003 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary G3UYF7 UniProtKB/Swiss-Prot
  Q3UWG8 UniProtKB/Swiss-Prot
  Q6Q758 UniProtKB/Swiss-Prot
  Q8CDR5 UniProtKB/Swiss-Prot
  Q9CUE5 UniProtKB/Swiss-Prot