Selenom (selenoprotein M) - Rat Genome Database

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Gene: Selenom (selenoprotein M) Mus musculus
Analyze
Symbol: Selenom
Name: selenoprotein M
RGD ID: 1622145
MGI Page MGI
Description: Predicted to enable oxidoreductase activity. Acts upstream of or within several processes, including adipose tissue development; corticosterone secretion; and response to selenium ion. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including cranium; hindbrain; sensory organ; ventral grey horn; and vibrissa. Orthologous to human SELENOM (selenoprotein M).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 1500040L08Rik; A230103K18; Se; Selm; Sepm
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,464,684 - 3,467,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,464,684 - 3,467,351 (+)EnsemblGRCm39 Ensembl
GRCm38113,514,684 - 3,517,351 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,514,684 - 3,517,351 (+)EnsemblGRCm38mm10GRCm38
MGSCv37113,414,705 - 3,417,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,414,889 - 3,417,353 (+)NCBIMGSCv36mm8
Celera114,005,593 - 4,008,243 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.47NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11839807   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:16258850   PMID:16319061   PMID:16602821   PMID:19769485   PMID:21267068   PMID:21795538   PMID:21873635   PMID:23880772   PMID:27645994   PMID:30648404  
PMID:35449600   PMID:36635091   PMID:37190890  


Genomics

Comparative Map Data
Selenom
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,464,684 - 3,467,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,464,684 - 3,467,351 (+)EnsemblGRCm39 Ensembl
GRCm38113,514,684 - 3,517,351 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,514,684 - 3,517,351 (+)EnsemblGRCm38mm10GRCm38
MGSCv37113,414,705 - 3,417,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,414,889 - 3,417,353 (+)NCBIMGSCv36mm8
Celera114,005,593 - 4,008,243 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.47NCBI
SELENOM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,104,777 - 31,107,568 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,104,772 - 31,120,069 (-)EnsemblGRCh38hg38GRCh38
GRCh372231,500,763 - 31,503,554 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,830,763 - 29,833,551 (-)NCBINCBI36Build 36hg18NCBI36
Celera2215,300,895 - 15,303,683 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,462,570 - 14,465,358 (-)NCBIHuRef
CHM1_12231,460,600 - 31,463,388 (-)NCBICHM1_1
T2T-CHM13v2.02231,568,276 - 31,571,067 (-)NCBIT2T-CHM13v2.0
Selenom
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,619,453 - 82,622,056 (+)NCBIGRCr8
mRatBN7.21478,395,826 - 78,398,429 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,395,826 - 78,398,429 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,837,015 - 82,839,618 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,077,121 - 84,079,724 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,522,884 - 80,525,488 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,752,393 - 83,754,975 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,752,393 - 83,754,973 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01484,440,340 - 84,442,922 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,157,831 - 84,160,413 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1477,308,292 - 77,310,874 (+)NCBICelera
Cytogenetic Map14q21NCBI
Selenom
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,294,503 - 5,296,748 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554555,294,317 - 5,303,621 (-)NCBIChiLan1.0ChiLan1.0
SELENOM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,060,364 - 41,063,439 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,758,865 - 43,761,940 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,128,513 - 12,131,653 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,966,405 - 29,981,171 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,966,602 - 29,969,137 (-)Ensemblpanpan1.1panPan2
SELENOM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,108,342 - 24,111,005 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,108,344 - 24,111,005 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,978,426 - 23,981,088 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,491,085 - 24,493,748 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,491,279 - 24,493,748 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,194,481 - 24,197,142 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,456,479 - 24,459,142 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,517,767 - 24,520,429 (-)NCBIUU_Cfam_GSD_1.0
Selenom
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118117,028,301 - 117,030,935 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755286,030 - 288,246 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936755285,836 - 288,501 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SELENOM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,902,864 - 47,905,440 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,902,862 - 47,905,350 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21451,014,556 - 51,017,049 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SELENOM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,996,307 - 13,999,083 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045112,120,543 - 112,123,317 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Selenom
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,582,446 - 7,584,673 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,582,259 - 7,584,903 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Selenom
79 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:515
Count of miRNA genes:304
Interacting mature miRNAs:332
Transcripts:ENSMUST00000094469, ENSMUST00000123677, ENSMUST00000131865
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
UniSTS:236496  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38113,517,005 - 3,517,324UniSTSGRCm38
MGSCv37113,417,008 - 3,417,327UniSTSGRCm37
Celera114,007,897 - 4,008,216UniSTS
Cytogenetic Map11A1UniSTS
RH141532  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38113,517,569 - 3,517,763UniSTSGRCm38
MGSCv37113,417,572 - 3,417,766UniSTSGRCm37
Celera114,008,461 - 4,008,655UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map11A2-A3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK018791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL713875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW049879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY043488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB589016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC147332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC147333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI731890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK787580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000094469   ⟹   ENSMUSP00000092041
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,464,867 - 3,467,351 (+)Ensembl
GRCm38.p6 Ensembl113,514,867 - 3,517,351 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123677
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,464,684 - 3,467,348 (+)Ensembl
GRCm38.p6 Ensembl113,514,684 - 3,517,348 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131865
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl113,464,702 - 3,467,130 (+)Ensembl
GRCm38.p6 Ensembl113,514,702 - 3,517,130 (+)Ensembl
RefSeq Acc Id: NM_053267   ⟹   NP_444497
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39113,464,684 - 3,467,351 (+)NCBI
GRCm38113,514,684 - 3,517,351 (+)NCBI
MGSCv37113,414,705 - 3,417,354 (+)RGD
Celera114,005,593 - 4,008,243 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_444497   ⟸   NM_053267
- Peptide Label: precursor
- UniProtKB: Q8CBT7 (UniProtKB/Swiss-Prot),   Q3V374 (UniProtKB/Swiss-Prot),   B2RVS9 (UniProtKB/Swiss-Prot),   Q8VCJ0 (UniProtKB/Swiss-Prot),   Q8VHC3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000092041   ⟸   ENSMUST00000094469

Promoters
RGD ID:6822049
Promoter ID:MM_KWN:6171
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_053267,   OTTMUST00000011155,   OTTMUST00000011156
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36113,414,691 - 3,415,191 (+)MPROMDB
RGD ID:8673736
Promoter ID:EPDNEW_M14899
Type:initiation region
Name:Selenom_1
Description:Mus musculus selenoprotein M , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38113,514,885 - 3,514,945EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2149786 AgrOrtholog
Ensembl Genes ENSMUSG00000075702 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000094469 ENTREZGENE
  ENSMUST00000094469.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.30.50 UniProtKB/Swiss-Prot
InterPro Sep15/SelM_sf UniProtKB/Swiss-Prot
  Sep15_SelM UniProtKB/Swiss-Prot
  Sep15_SelM_dom UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
KEGG Report mmu:114679 UniProtKB/Swiss-Prot
MGD MGI:2149786 ENTREZGENE
NCBI Gene 114679 ENTREZGENE
PANTHER PTHR13077 UniProtKB/Swiss-Prot
  SELENOPROTEIN M UniProtKB/Swiss-Prot
Pfam Sep15_SelM UniProtKB/Swiss-Prot
PhenoGen Selenom PhenoGen
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot
UniProt B2RVS9 ENTREZGENE
  Q3V374 ENTREZGENE
  Q8CBT7 ENTREZGENE
  Q8VCJ0 ENTREZGENE
  Q8VHC3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2RVS9 UniProtKB/Swiss-Prot
  Q3V374 UniProtKB/Swiss-Prot
  Q8CBT7 UniProtKB/Swiss-Prot
  Q8VCJ0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-25 Selenom  selenoprotein M  Selm  selenoprotein M  Symbol and/or name change 5135510 APPROVED