Cd300ld (CD300 molecule like family member d) - Rat Genome Database
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Gene: Cd300ld (CD300 molecule like family member d) Mus musculus
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Symbol: Cd300ld
Name: CD300 molecule like family member d
RGD ID: 1622107
MGI Page MGI
Description: Exhibits virus receptor activity. Involved in regulation of interleukin-6 production and regulation of tumor necrosis factor production. Localizes to plasma membrane. Orthologous to human CD300LD (CD300 molecule like family member d); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4732429D16Rik; CD300 antigen like family member D; CD300 molecule-like family member d; Cd300ld1; Clm; clm-5; CLM5; CMRF35-like molecule 5; leukocyte mono-Ig-like receptor 4; LMIR4; MA; MAIR-4; MAIR-IV; myeloid-associated immunoglobulin (Ig)-like receptor IV; myeloid-associated immunoglobulin-like receptor 4; novel immunoglobulin V-set protein (Clm5); RP23-331L12.3
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911114,873,269 - 114,880,712 (-)NCBIGRCm39mm39
GRCm3811114,982,443 - 114,989,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11114,982,274 - 114,989,922 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711114,843,757 - 114,851,200 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611114,798,533 - 114,805,976 (-)NCBImm8
Celera11126,735,044 - 126,740,241 (-)NCBICelera
Cytogenetic Map11E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14662855   PMID:16141072   PMID:16141073   PMID:17438331   PMID:17543387   PMID:20817736  
PMID:21677750   PMID:21873635   PMID:27540007   PMID:27681626  


Genomics

Comparative Map Data
Cd300ld
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911114,873,269 - 114,880,712 (-)NCBIGRCm39mm39
GRCm3811114,982,443 - 114,989,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11114,982,274 - 114,989,922 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711114,843,757 - 114,851,200 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611114,798,533 - 114,805,976 (-)NCBImm8
Celera11126,735,044 - 126,740,241 (-)NCBICelera
Cytogenetic Map11E2NCBI
CD300LD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1774,579,365 - 74,592,283 (-)EnsemblGRCh38hg38GRCh38
GRCh381774,579,365 - 74,592,283 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371772,576,111 - 72,588,370 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,087,099 - 70,100,011 (-)NCBINCBI36hg18NCBI36
Celera1769,168,587 - 69,180,824 (-)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1767,985,175 - 67,997,433 (-)NCBIHuRef
CHM1_11772,640,672 - 72,652,927 (-)NCBICHM1_1
Cd300ld
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010104,847,315 - 104,895,630 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010103,398,095 - 103,438,905 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410104,962,447 - 104,965,459 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1098,660,969 - 98,693,311 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
CD300LD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11774,082,596 - 74,095,525 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1774,082,596 - 74,095,525 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01768,525,616 - 68,538,554 (-)NCBIMhudiblu_PPA_v0panPan3
LOC102151751
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.195,855,245 - 5,862,714 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC100515852
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1126,596,206 - 6,616,554 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2126,585,759 - 6,605,507 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD300LD
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1647,056,425 - 47,071,284 (+)Ensembl
ChlSab1.11647,056,402 - 47,071,442 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185954085119954085Mouse
15039374Adip29_madiposity 29 (mouse)1186717494120717494Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186717494120717494Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186717494120717494Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194172953118131898Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194300000119000000Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94546357118131898Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195513139122082543Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195513139122082543Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196246848122082543Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196919310122082543Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198461783122082543Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198609643122082543Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199363361122082543Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100167277122082543Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100363360120996339Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101131764122082543Mouse
4141612Cia40_mcollagen induced arthritis 40 (mouse)Not determined11103383166115130618Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:603
Count of miRNA genes:439
Interacting mature miRNAs:496
Transcripts:ENSMUST00000045075
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000045075   ⟹   ENSMUSP00000047022
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11114,982,274 - 114,989,922 (-)Ensembl
RefSeq Acc Id: NM_145437   ⟹   NP_663412
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911114,873,269 - 114,880,712 (-)NCBI
GRCm3811114,982,443 - 114,989,886 (-)ENTREZGENE
MGSCv3711114,843,757 - 114,851,200 (-)RGD
Celera11126,735,044 - 126,770,144 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_663412   ⟸   NM_145437
- Peptide Label: precursor
- UniProtKB: Q8VCH2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000047022   ⟸   ENSMUST00000045075
Protein Domains
IG   Ig-like V-type

Promoters
RGD ID:6821883
Promoter ID:MM_KWN:10493
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Spleen
Transcripts:OTTMUST00000007756
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611114,851,241 - 114,852,202 (-)MPROMDB
RGD ID:8677296
Promoter ID:EPDNEW_M16679
Type:initiation region
Name:Cd300ld_1
Description:Mus musculus CD300 molecule like family member d , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811114,989,900 - 114,989,960EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442358 AgrOrtholog
Ensembl Genes ENSMUSG00000034641 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000047022 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000045075 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:217305 UniProtKB/Swiss-Prot
MGD MGI:2442358 ENTREZGENE
NCBI Gene 217305 ENTREZGENE
Pfam V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cd300ld PhenoGen
SMART SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.275986 ENTREZGENE
UniProt A0A1C9ZWJ7_MOUSE UniProtKB/TrEMBL
  CLM5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8BRU3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-17 Cd300ld  CD300 molecule like family member d    CD300 molecule-like family member d  Symbol and/or name change 5135510 APPROVED