Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | increases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of GPRIN3 mRNA | CTD | PMID:29097150 | 17beta-estradiol | increases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of GPRIN3 mRNA | CTD | PMID:32145629 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of GPRIN3 mRNA | CTD | PMID:26377647 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of GPRIN3 mRNA | CTD | PMID:25172293 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of GPRIN3 mRNA | CTD | PMID:20188158 | 3-chloropropane-1,2-diol | increases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of GPRIN3 mRNA | CTD | PMID:28522335 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of GPRIN3 gene | CTD | PMID:31683443 | 6-propyl-2-thiouracil | increases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of GPRIN3 mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of GPRIN3 mRNA | CTD | PMID:30047161 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of GPRIN3 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of GPRIN3 mRNA | CTD | PMID:32234424 | aflatoxin B1 | decreases methylation | ISO | GPRIN3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of GPRIN3 gene and Aflatoxin B1 results in decreased methylation of GPRIN3 intron | CTD | PMID:27153756 and PMID:30157460 | amphetamine | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of GPRIN3 mRNA | CTD | PMID:30779732 | antirheumatic drug | decreases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of GPRIN3 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of GPRIN3 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | GPRIN3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GPRIN3 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | GPRIN3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GPRIN3 gene | CTD | PMID:25304211 | atrazine | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Atrazine results in increased expression of GPRIN3 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of GPRIN3 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of GPRIN3 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | GPRIN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of GPRIN3 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of GPRIN3 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | decreases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of GPRIN3 mRNA | CTD | PMID:22178795 | benzo[b]fluoranthene | decreases expression | EXP | | 6480464 | benzo(b)fluoranthene results in decreased expression of GPRIN3 mRNA | CTD | PMID:26377693 | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of GPRIN3 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of GPRIN3 mRNA | CTD | PMID:25181051 | bisphenol A | affects expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of GPRIN3 mRNA | CTD | PMID:32145629 | bisphenol A | increases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of GPRIN3 mRNA | CTD | PMID:29097150 | bromobenzene | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | bromobenzene results in decreased expression of GPRIN3 mRNA | CTD | PMID:32479839 | butanal | decreases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of GPRIN3 mRNA | CTD | PMID:26079696 | carbon nanotube | affects expression | EXP | | 6480464 | Nanotubes and Carbon affects the expression of GPRIN3 mRNA | CTD | PMID:25554681 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | chrysene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of GPRIN3 mRNA | CTD | PMID:27858113 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of GPRIN3 mRNA | CTD | PMID:30629241 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of GPRIN3 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases methylation | ISO | GPRIN3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of GPRIN3 promoter | CTD | PMID:27989131 | dibenz[a,h]anthracene | decreases expression | EXP | | 6480464 | 1 more ... | CTD | PMID:26377693 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GPRIN3 mRNA | CTD | PMID:30529165 | dioxygen | multiple interactions | ISO | Gprin3 (Rattus norvegicus) | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of GPRIN3 mRNA | CTD | PMID:33729688 | endosulfan | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of GPRIN3 mRNA | CTD | PMID:29391264 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of GPRIN3 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | GPRIN3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of GPRIN3 protein | CTD | PMID:37730182 | hydrogen peroxide | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of GPRIN3 mRNA | CTD | PMID:18951874 | lead(0) | affects expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Lead affects the expression of GPRIN3 mRNA | CTD | PMID:28903495 | lipopolysaccharide | multiple interactions | ISO | GPRIN3 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | lipopolysaccharide | decreases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of GPRIN3 mRNA | CTD | PMID:35811015 | metformin | increases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Metformin results in increased expression of GPRIN3 mRNA | CTD | PMID:31324951 | methimazole | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of GPRIN3 mRNA | CTD | PMID:30047161 | N-Nitrosopyrrolidine | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in increased expression of GPRIN3 mRNA | CTD | PMID:32234424 | nickel atom | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Nickel results in increased expression of GPRIN3 mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of GPRIN3 mRNA | CTD | PMID:34911549 | PCB138 | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | pentanal | decreases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | pentanal results in decreased expression of GPRIN3 mRNA | CTD | PMID:26079696 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of GPRIN3 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of GPRIN3 mRNA | CTD | PMID:27153767 | permethrin | decreases expression | EXP | | 6480464 | Permethrin results in decreased expression of GPRIN3 mRNA | CTD | PMID:30629241 | phenformin | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Phenformin results in decreased expression of GPRIN3 mRNA | CTD | PMID:31324951 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of GPRIN3 mRNA | CTD | PMID:23091169 | rotenone | increases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of GPRIN3 mRNA | CTD | PMID:28374803 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | GPRIN3 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | silicon dioxide | decreases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of GPRIN3 mRNA | CTD | PMID:25895662 | sunitinib | increases expression | ISO | GPRIN3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of GPRIN3 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of GPRIN3 mRNA | CTD | PMID:31919559 | tetraphene | decreases expression | EXP | | 6480464 | benz(a)anthracene results in decreased expression of GPRIN3 mRNA | CTD | PMID:26377693 | tetraphene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of GPRIN3 mRNA | CTD | PMID:27858113 | thioacetamide | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of GPRIN3 mRNA | CTD | PMID:34492290 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of GPRIN3 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | ISO | GPRIN3 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of GPRIN3 gene | CTD | PMID:29154799 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of GPRIN3 mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | Gprin3 (Rattus norvegicus) | 6480464 | Valproic Acid results in decreased expression of GPRIN3 mRNA | CTD | PMID:29427782 | |