Gprin3 (GPRIN family member 3) - Rat Genome Database

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Gene: Gprin3 (GPRIN family member 3) Mus musculus
Analyze
Symbol: Gprin3
Name: GPRIN family member 3
RGD ID: 1622029
MGI Page MGI
Description: Predicted to be involved in neuron projection development. Predicted to be active in plasma membrane. Orthologous to human GPRIN3 (GPRIN family member 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C030038J10Rik; C730021L23; G protein-regulated inducer of neurite outgrowth 3; GRIN3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39659,317,988 - 59,403,291 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl659,324,211 - 59,403,279 (-)EnsemblGRCm39 Ensembl
GRCm38659,344,500 - 59,426,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl659,347,226 - 59,426,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv37659,302,455 - 59,376,284 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36659,282,039 - 59,355,868 (-)NCBIMGSCv36mm8
Celera661,507,631 - 61,580,997 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map628.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15368895   PMID:15488195   PMID:15572359   PMID:16141072   PMID:16141073   PMID:21267068  
PMID:21873635   PMID:29500670   PMID:30728831   PMID:31040226   PMID:31363062  


Genomics

Comparative Map Data
Gprin3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39659,317,988 - 59,403,291 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl659,324,211 - 59,403,279 (-)EnsemblGRCm39 Ensembl
GRCm38659,344,500 - 59,426,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl659,347,226 - 59,426,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv37659,302,455 - 59,376,284 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36659,282,039 - 59,355,868 (-)NCBIMGSCv36mm8
Celera661,507,631 - 61,580,997 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map628.48NCBI
GPRIN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38489,236,383 - 89,307,800 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl489,236,383 - 89,307,800 (-)EnsemblGRCh38hg38GRCh38
GRCh37490,157,534 - 90,228,951 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36490,384,452 - 90,448,184 (-)NCBINCBI36Build 36hg18NCBI36
Celera487,461,582 - 87,525,350 (-)NCBICelera
Cytogenetic Map4q22.1NCBI
HuRef485,916,151 - 85,979,925 (-)NCBIHuRef
CHM1_1490,141,906 - 90,205,629 (-)NCBICHM1_1
T2T-CHM13v2.0492,567,541 - 92,638,966 (-)NCBIT2T-CHM13v2.0
Gprin3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8489,902,198 - 89,987,496 (-)NCBIGRCr8
mRatBN7.2488,572,062 - 88,657,369 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl488,563,607 - 88,657,429 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx493,791,405 - 93,876,684 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0489,566,737 - 89,652,018 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0487,920,508 - 88,013,444 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0489,690,678 - 89,778,302 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl489,693,280 - 89,695,928 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04154,507,201 - 154,594,720 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4488,376,454 - 88,378,742 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera483,319,305 - 83,406,225 (-)NCBICelera
Cytogenetic Map4q24NCBI
Gprin3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955405254,105 - 256,414 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955405253,917 - 265,309 (-)NCBIChiLan1.0ChiLan1.0
GPRIN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2387,245,292 - 87,312,167 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1487,507,487 - 87,574,345 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0481,530,662 - 81,597,530 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1492,250,618 - 92,345,452 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl492,257,125 - 92,259,455 (-)Ensemblpanpan1.1panPan2
GPRIN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13212,501,488 - 12,562,344 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3212,501,577 - 12,503,907 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3229,393,389 - 29,463,336 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03212,540,621 - 12,610,786 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3212,549,793 - 12,552,501 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.03212,452,854 - 12,523,002 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03227,392,979 - 27,463,135 (+)NCBIUU_Cfam_GSD_1.0
Gprin3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530128,843,048 - 28,905,994 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366851,656,084 - 1,658,384 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366851,649,740 - 1,712,958 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPRIN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.18129,818,975 - 129,878,509 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28139,266,055 - 139,341,917 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPRIN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1737,584,298 - 37,652,548 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl737,590,836 - 37,593,166 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603716,341,170 - 16,415,814 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gprin3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475716,938,060 - 16,940,276 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475716,931,759 - 17,007,924 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gprin3
2561 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:134
Count of miRNA genes:117
Interacting mature miRNAs:121
Transcripts:ENSMUST00000051065
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse
15039373Adip28_madiposity 28 (mouse)65628519490285194Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65628519490285194Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000051065   ⟹   ENSMUSP00000051805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl659,324,211 - 59,403,279 (-)Ensembl
GRCm38.p6 Ensembl659,347,226 - 59,426,294 (-)Ensembl
RefSeq Acc Id: NM_183183   ⟹   NP_899006
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39659,329,446 - 59,403,291 (-)NCBI
GRCm38659,352,461 - 59,426,306 (-)NCBI
MGSCv37659,302,455 - 59,376,284 (-)RGD
Celera661,507,631 - 61,580,997 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006506084   ⟹   XP_006506147
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39659,317,988 - 59,345,813 (-)NCBI
GRCm38659,344,500 - 59,368,828 (-)NCBI
Sequence:
RefSeq Acc Id: NP_899006   ⟸   NM_183183
- UniProtKB: Q69Z30 (UniProtKB/Swiss-Prot),   Q8BWS5 (UniProtKB/Swiss-Prot),   B2RQZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006506147   ⟸   XM_006506084
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000051805   ⟸   ENSMUST00000051065
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BWS5-F1-model_v2 AlphaFold Q8BWS5 1-763 view protein structure

Promoters
RGD ID:6839421
Promoter ID:MM_KWN:46197
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   Brain,   Kidney,   Liver,   Lung,   MEF_B4
Transcripts:ENSMUST00000051065
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36659,376,136 - 59,376,636 (-)MPROMDB
RGD ID:6889866
Promoter ID:EPDNEW_M8384
Type:single initiation site
Name:Gprin3_2
Description:Mus musculus GPRIN family member 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8385  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38659,409,198 - 59,409,258EPDNEW
RGD ID:6889868
Promoter ID:EPDNEW_M8385
Type:multiple initiation site
Name:Gprin3_1
Description:Mus musculus GPRIN family member 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8384  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38659,426,306 - 59,426,366EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924785 AgrOrtholog
Ensembl Genes ENSMUSG00000045441 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000051065 ENTREZGENE
  ENSMUST00000051065.6 UniProtKB/Swiss-Prot
InterPro GPRIN2-like/GPRIN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GRIN_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:243385 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1924785 ENTREZGENE
NCBI Gene 243385 ENTREZGENE
PANTHER G PROTEIN-REGULATED INDUCER OF NEURITE OUTGROWTH 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15718 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GRIN_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gprin3 PhenoGen
UniProt B2RQZ6 ENTREZGENE, UniProtKB/TrEMBL
  GRIN3_MOUSE UniProtKB/Swiss-Prot
  Q69Z30 ENTREZGENE
  Q8BWS5 ENTREZGENE
UniProt Secondary Q69Z30 UniProtKB/Swiss-Prot