Trim61 (tripartite motif-containing 61) - Rat Genome Database
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Gene: Trim61 (tripartite motif-containing 61) Mus musculus
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Symbol: Trim61
Name: tripartite motif-containing 61
RGD ID: 1621996
MGI Page MGI
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to localize to cytoplasm. Is expressed in early conceptus; secondary oocyte; and testis. Orthologous to human TRIM61 (tripartite motif containing 61); INTERACTS WITH clofibrate; N-ethyl-N-nitrosourea; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2czf61; AU018704; C85201; E330039K03Rik; putative tripartite motif-containing protein 61; ring finger protein 35; Rnf; Rnf35
RGD Orthologs
Human
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,465,628 - 65,471,340 (-)NCBIGRCm39mm39
GRCm38865,012,976 - 65,018,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl865,012,987 - 65,018,523 (-)EnsemblGRCm38mm10GRCm38
MGSCv37867,536,875 - 67,542,587 (-)NCBIGRCm37mm9NCBIm37
MGSCv36867,941,979 - 67,947,555 (-)NCBImm8
Celera867,574,361 - 67,582,546 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12160726   PMID:12433986   PMID:12466851   PMID:12477932   PMID:15516209  
PMID:15618518   PMID:15994318   PMID:16141072   PMID:16141073   PMID:18287559   PMID:21873635   PMID:26902285  


Genomics

Comparative Map Data
Trim61
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,465,628 - 65,471,340 (-)NCBIGRCm39mm39
GRCm38865,012,976 - 65,018,688 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl865,012,987 - 65,018,523 (-)EnsemblGRCm38mm10GRCm38
MGSCv37867,536,875 - 67,542,587 (-)NCBIGRCm37mm9NCBIm37
MGSCv36867,941,979 - 67,947,555 (-)NCBImm8
Celera867,574,361 - 67,582,546 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
TRIM61
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4164,954,446 - 164,977,668 (-)EnsemblGRCh38hg38GRCh38
GRCh384164,954,446 - 164,977,657 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374165,875,598 - 165,898,818 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364166,095,048 - 166,118,268 (-)NCBINCBI36hg18NCBI36
Celera4163,207,628 - 163,230,821 (-)NCBI
Cytogenetic Map4q32.3NCBI
HuRef4161,629,233 - 161,652,427 (-)NCBIHuRef
CHM1_14165,852,150 - 165,875,369 (-)NCBICHM1_1
TRIM61
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v04157,161,242 - 157,178,793 (+)NCBIMhudiblu_PPA_v0panPan3
TRIM61
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17111,306,850 - 111,308,827 (+)NCBI

Position Markers
RH127152  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38865,012,992 - 65,013,234UniSTSGRCm38
MGSCv37867,536,891 - 67,537,133UniSTSGRCm37
Celera867,574,377 - 67,574,619UniSTS
Cytogenetic Map8B3.1-3.2UniSTS
Whitehead/MRC_RH8708.4UniSTS
RH136249  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38865,013,051 - 65,013,262UniSTSGRCm38
MGSCv37867,536,950 - 67,537,161UniSTSGRCm37
Celera867,574,436 - 67,574,647UniSTS
Cytogenetic Map8B3.1-3.2UniSTS
UniSTS:235902  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38865,013,857 - 65,014,069UniSTSGRCm38
MGSCv37867,537,756 - 67,537,968UniSTSGRCm37
Celera867,575,242 - 67,575,454UniSTS
Cytogenetic Map8B3.1-3.2UniSTS
PMC137171P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38865,014,487 - 65,014,878UniSTSGRCm38
MGSCv37867,538,386 - 67,538,777UniSTSGRCm37
Celera867,575,872 - 67,576,263UniSTS
Cytogenetic Map8B3.1-3.2UniSTS
Trim61  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38865,013,256 - 65,014,878UniSTSGRCm38
MGSCv37867,537,155 - 67,538,777UniSTSGRCm37
Celera867,574,641 - 67,576,263UniSTS
Cytogenetic Map8B3.1-3.2UniSTS
Rnf35  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38865,013,256 - 65,013,790UniSTSGRCm38
MGSCv37867,537,155 - 67,537,689UniSTSGRCm37
Celera867,574,641 - 67,575,175UniSTS
Cytogenetic Map8B3.1-3.2UniSTS
cM Map8 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1301936Trigq2_mtriglyceride QTL 2 (mouse)Not determined83383736267837502Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:84
Interacting mature miRNAs:84
Transcripts:ENSMUST00000078409
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000078409   ⟹   ENSMUSP00000077513
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl865,012,990 - 65,018,523 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211310   ⟹   ENSMUSP00000147962
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl865,012,987 - 65,014,510 (-)Ensembl
RefSeq Acc Id: NM_001177551   ⟹   NP_001171022
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39865,465,628 - 65,471,340 (-)NCBI
GRCm38865,012,976 - 65,018,688 (-)ENTREZGENE
MGSCv37867,536,875 - 67,542,587 (-)RGD
Celera867,574,361 - 67,582,546 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_153110   ⟹   NP_694750
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39865,465,628 - 65,471,340 (-)NCBI
GRCm38865,012,976 - 65,018,688 (-)ENTREZGENE
MGSCv37867,536,875 - 67,542,587 (-)RGD
Celera867,574,361 - 67,582,546 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_694750   ⟸   NM_153110
- UniProtKB: Q6P242 (UniProtKB/TrEMBL),   Q8JZK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001171022   ⟸   NM_001177551
- UniProtKB: Q8JZK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000147962   ⟸   ENSMUST00000211310
RefSeq Acc Id: ENSMUSP00000077513   ⟸   ENSMUST00000078409
Protein Domains
B30.2/SPRY   RING-type


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2387432 AgrOrtholog
Ensembl Genes ENSMUSG00000109718 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000077513 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000147962 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078409 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000211310 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Butyrophylin UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY/PRY_TRIM60 UniProtKB/TrEMBL
  SPRY_rcpt UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report mmu:260296 UniProtKB/TrEMBL
MGD MGI:2387432 ENTREZGENE
NCBI Gene 260296 ENTREZGENE
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
PhenoGen Trim61 PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART PRY UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
UniProt A0A1B0GSJ5_MOUSE UniProtKB/TrEMBL
  Q3UWX5_MOUSE UniProtKB/TrEMBL
  Q6P242 ENTREZGENE, UniProtKB/TrEMBL
  Q8JZK6 ENTREZGENE, UniProtKB/TrEMBL
  Q8K3L1_MOUSE UniProtKB/TrEMBL