Ceacam16 (CEA cell adhesion molecule 16) - Rat Genome Database

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Gene: Ceacam16 (CEA cell adhesion molecule 16) Mus musculus
Analyze
Symbol: Ceacam16
Name: CEA cell adhesion molecule 16
RGD ID: 1621965
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Involved in sensory perception of sound. Located in stereocilium tip. Is expressed in brainstem; metanephros; submandibular gland; and testis. Used to study autosomal dominant nonsyndromic deafness 4A. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 4B and autosomal recessive nonsyndromic deafness 113. Orthologous to human CEACAM16 (CEA cell adhesion molecule 16, tectorial membrane component).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: carcinoembryonic antigen-related cell adhesion molecule 16; CEA-related cell adhesion molecule 16; Gm769
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,586,022 - 19,595,224 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,586,022 - 19,595,224 (-)EnsemblGRCm39 Ensembl
GRCm38719,852,097 - 19,871,426 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,852,097 - 19,861,299 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,437,446 - 20,446,648 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36719,010,622 - 19,019,758 (-)NCBIMGSCv36mm8
Celera717,260,143 - 17,269,345 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16139472   PMID:16141072   PMID:16141073   PMID:21368133   PMID:21677750   PMID:21873635  
PMID:22544735   PMID:24194600   PMID:25080593   PMID:27626380   PMID:28700664   PMID:31249509   PMID:34555361   PMID:37279265  


Genomics

Comparative Map Data
Ceacam16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,586,022 - 19,595,224 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,586,022 - 19,595,224 (-)EnsemblGRCm39 Ensembl
GRCm38719,852,097 - 19,871,426 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,852,097 - 19,861,299 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,437,446 - 20,446,648 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36719,010,622 - 19,019,758 (-)NCBIMGSCv36mm8
Celera717,260,143 - 17,269,345 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.95NCBI
CEACAM16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381944,699,151 - 44,710,718 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1944,699,151 - 44,710,718 (+)EnsemblGRCh38hg38GRCh38
GRCh371945,202,421 - 45,213,990 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361949,894,198 - 49,905,826 (+)NCBINCBI36Build 36hg18NCBI36
Celera1942,006,785 - 42,018,350 (+)NCBICelera
Cytogenetic Map19q13.31-q13.32NCBI
HuRef1941,634,688 - 41,646,253 (+)NCBIHuRef
CHM1_11945,205,101 - 45,216,664 (+)NCBICHM1_1
T2T-CHM13v2.01947,523,898 - 47,535,467 (+)NCBIT2T-CHM13v2.0
Ceacam16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,642,925 - 88,652,821 (-)NCBIGRCr8
mRatBN7.2179,514,975 - 79,524,871 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,514,975 - 79,524,871 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,909,445 - 84,919,347 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0193,460,172 - 93,470,165 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,664,566 - 86,674,468 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,773,819 - 80,783,898 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,773,819 - 80,783,898 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,039,102 - 82,049,181 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,166,356 - 79,176,252 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,201,314 - 79,282,028 (-)NCBI
Celera173,972,883 - 73,982,778 (-)NCBICelera
Cytogenetic Map1q21NCBI
Ceacam16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555551,859,220 - 1,878,912 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555551,859,220 - 1,878,912 (+)NCBIChiLan1.0ChiLan1.0
CEACAM16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22050,861,248 - 50,868,036 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11952,733,189 - 52,739,986 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01941,649,625 - 41,659,151 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,251,835 - 50,262,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,254,123 - 50,262,808 (+)Ensemblpanpan1.1panPan2
CEACAM16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,652,362 - 110,661,173 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,652,584 - 110,660,334 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1110,134,189 - 110,141,936 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01111,215,199 - 111,223,185 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1111,215,193 - 111,223,362 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,857,177 - 110,864,940 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,492,839 - 110,500,578 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,362,287 - 111,370,066 (-)NCBIUU_Cfam_GSD_1.0
Ceacam16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,043,394 - 17,050,657 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,391,814 - 1,396,571 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,390,737 - 1,396,472 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CEACAM16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl651,220,812 - 51,231,761 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1651,217,085 - 51,228,458 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,116,033 - 47,127,421 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CEACAM16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,179,822 - 38,189,731 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl638,180,658 - 38,187,342 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607317,744,958 - 17,756,874 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ceacam16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249071,631,279 - 1,638,266 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249071,627,941 - 1,638,436 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ceacam16
249 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:230
Count of miRNA genes:206
Interacting mature miRNAs:219
Transcripts:ENSMUST00000014830
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000014830   ⟹   ENSMUSP00000014830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl719,586,022 - 19,595,224 (-)Ensembl
GRCm38.p6 Ensembl719,852,097 - 19,861,299 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208198   ⟹   ENSMUSP00000147247
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl719,586,023 - 19,590,161 (-)Ensembl
GRCm38.p6 Ensembl719,852,098 - 19,856,236 (-)Ensembl
RefSeq Acc Id: NM_001033419   ⟹   NP_001028591
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,586,022 - 19,595,224 (-)NCBI
GRCm38719,852,097 - 19,861,299 (-)NCBI
MGSCv37720,437,446 - 20,446,648 (-)RGD
Celera717,260,143 - 17,269,345 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006540112   ⟹   XP_006540175
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,587,769 - 19,595,218 (-)NCBI
GRCm38719,853,837 - 19,871,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011250607   ⟹   XP_011248909
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,586,022 - 19,595,218 (-)NCBI
GRCm38719,852,097 - 19,871,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030242689   ⟹   XP_030098549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39719,586,022 - 19,595,218 (-)NCBI
GRCm38719,852,097 - 19,871,426 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001028591   ⟸   NM_001033419
- Peptide Label: precursor
- UniProtKB: B2RUD6 (UniProtKB/Swiss-Prot),   E9QA28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006540175   ⟸   XM_006540112
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011248909   ⟸   XM_011250607
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030098549   ⟸   XM_030242689
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000014830   ⟸   ENSMUST00000014830
RefSeq Acc Id: ENSMUSP00000147247   ⟸   ENSMUST00000208198
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9QA28-F1-model_v2 AlphaFold E9QA28 1-426 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685615 AgrOrtholog
Ensembl Genes ENSMUSG00000014686 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000014830 ENTREZGENE
  ENSMUST00000014830.8 UniProtKB/Swiss-Prot
  ENSMUST00000208198.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
KEGG Report mmu:330483 UniProtKB/Swiss-Prot
MGD MGI:2685615 ENTREZGENE
NCBI Gene 330483 ENTREZGENE
PANTHER CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 16 UniProtKB/Swiss-Prot
  CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19 UniProtKB/Swiss-Prot
  CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5 UniProtKB/TrEMBL
  CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8 UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/Swiss-Prot
  V-set UniProtKB/Swiss-Prot
PhenoGen Ceacam16 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140LJK4_MOUSE UniProtKB/TrEMBL
  B2RUD6 ENTREZGENE
  CEA16_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B2RUD6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-14 Ceacam16  CEA cell adhesion molecule 16  Ceacam16  carcinoembryonic antigen-related cell adhesion molecule 16  Symbol and/or name change 5135510 APPROVED