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Gene: Ksr2 (kinase suppressor of ras 2) Mus musculus
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Symbol: Ksr2
Name: kinase suppressor of ras 2
Description: ENCODES a protein that exhibits MAP-kinase scaffold activity; mitogen-activated protein kinase kinase binding; INVOLVED IN calcium-mediated signaling; positive regulation of cold-induced thermogenesis; positive regulation of MAPK cascade; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ASSOCIATED WITH increased percent body fat/body weight; obese; ASSOCIATED WITH morbid obesity (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN cytosol; plasma membrane; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: testes-kinase suppressor of ras 2 isoform
Orthologs:
Homo sapiens (human) : KSR2 (kinase suppressor of ras 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ksr2 (kinase suppressor of ras 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ksr2 (kinase suppressor of ras 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KSR2 (kinase suppressor of ras 2)
Canis lupus familiaris (dog) : KSR2 (kinase suppressor of ras 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ksr2 (kinase suppressor of ras 2)
Sus scrofa (pig) : KSR2 (kinase suppressor of ras 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm385117,414,002 - 117,767,996 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375117,864,009 - 118,213,329 (+)NCBIGRCm37mm9NCBIm37
MGSCv365115,410,053 - 115,812,068 (+)NCBImm8
MGSCv365117,675,030 - 117,816,972 (+)NCBImm8
Celera5114,504,421 - 114,858,271 (+)NCBICelera
Cytogenetic Map5 FNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ksr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1621959
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.