Iho1 (interactor of HORMAD1 1) - Rat Genome Database
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Gene: Iho1 (interactor of HORMAD1 1) Mus musculus
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Symbol: Iho1
Name: interactor of HORMAD1 1
RGD ID: 1621878
MGI Page MGI
Description: Involved in gamete generation; meiosis I cell cycle process; and regulation of homologous chromosome segregation. Localizes to condensed nuclear chromosome. Is expressed in Meckel's cartilage; head bone; lung; and ventral grey horn. Orthologous to human IHO1 (interactor of HORMAD1 1); INTERACTS WITH 4,4'-sulfonyldiphenol; sodium fluoride; bisphenol A (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ccdc36; coiled-coil domain containing 36; coiled-coil domain-containing protein 36; Ih; interactor of HORMAD1 protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,280,691 - 108,309,040 (-)NCBIGRCm39mm39
GRCm389108,403,492 - 108,431,841 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,403,611 - 108,428,484 (-)EnsemblGRCm38mm10GRCm38
MGSCv379108,305,952 - 108,330,813 (-)NCBIGRCm37mm9NCBIm37
MGSCv369108,261,591 - 108,294,188 (-)NCBImm8
Celera9108,012,831 - 108,037,747 (-)NCBICelera
Cytogenetic Map9F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:27723721   PMID:30569039   PMID:31000436   PMID:32325033  


Genomics

Comparative Map Data
Iho1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,280,691 - 108,309,040 (-)NCBIGRCm39mm39
GRCm389108,403,492 - 108,431,841 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,403,611 - 108,428,484 (-)EnsemblGRCm38mm10GRCm38
MGSCv379108,305,952 - 108,330,813 (-)NCBIGRCm37mm9NCBIm37
MGSCv369108,261,591 - 108,294,188 (-)NCBImm8
Celera9108,012,831 - 108,037,747 (-)NCBICelera
Cytogenetic Map9F2NCBI
IHO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,198,428 - 49,258,106 (+)EnsemblGRCh38hg38GRCh38
GRCh38349,198,428 - 49,258,106 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,235,861 - 49,295,636 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,210,865 - 49,270,160 (+)NCBINCBI36hg18NCBI36
Celera349,193,717 - 49,258,916 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,293,567 - 49,352,860 (+)NCBIHuRef
CHM1_1349,188,591 - 49,248,327 (+)NCBICHM1_1
Iho1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08117,182,484 - 117,215,390 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,183,343 - 117,211,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,531,078 - 116,559,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8108,394,590 - 108,425,677 (-)NCBICelera
Cytogenetic Map8q32NCBI
Iho1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555321,198,316 - 1,226,875 (+)NCBIChiLan1.0ChiLan1.0
IHO1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,217,333 - 50,260,487 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,239,250 - 50,259,890 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,122,120 - 49,181,228 (+)NCBIMhudiblu_PPA_v0panPan3
IHO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2039,965,480 - 39,990,756 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12039,964,629 - 40,006,726 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Iho1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936529905,692 - 929,896 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IHO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,775,668 - 31,836,911 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,802,963 - 31,836,911 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,060,241 - 35,067,709 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IHO1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,593,516 - 10,653,519 (+)NCBI
Iho1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,208,648 - 3,249,281 (+)NCBI

Position Markers
D9Mit184  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389108,413,879 - 108,414,013UniSTSGRCm38
MGSCv379108,316,210 - 108,316,344UniSTSGRCm37
Celera9108,023,156 - 108,023,284UniSTS
Cytogenetic Map9F2UniSTS
cM Map960.0UniSTS
Whitehead Genetic960.1UniSTS
Whitehead_YAC9 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:412
Count of miRNA genes:314
Interacting mature miRNAs:344
Transcripts:ENSMUST00000076592
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000076592   ⟹   ENSMUSP00000075898
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9108,403,611 - 108,428,484 (-)Ensembl
RefSeq Acc Id: NM_001135198   ⟹   NP_001128670
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,280,691 - 108,309,025 (-)NCBI
GRCm389108,403,492 - 108,431,826 (-)NCBI
MGSCv379108,305,952 - 108,330,813 (-)RGD
Celera9108,012,831 - 108,037,747 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001379658   ⟹   NP_001366587
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,280,691 - 108,309,025 (-)NCBI
GRCm389108,403,492 - 108,431,826 (-)NCBI
RefSeq Acc Id: XM_006511766   ⟹   XP_006511829
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,280,731 - 108,305,681 (-)NCBI
GRCm389108,403,532 - 108,414,115 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242895   ⟹   XP_011241197
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,280,731 - 108,309,040 (-)NCBI
GRCm389108,403,532 - 108,431,841 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242896   ⟹   XP_011241198
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,280,731 - 108,305,681 (-)NCBI
GRCm389108,403,532 - 108,428,482 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036155100   ⟹   XP_036010993
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,280,731 - 108,305,681 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001128670   ⟸   NM_001135198
- UniProtKB: Q6PDM4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006511829   ⟸   XM_006511766
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011241197   ⟸   XM_011242895
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011241198   ⟸   XM_011242896
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001366587   ⟸   NM_001379658
RefSeq Acc Id: ENSMUSP00000075898   ⟸   ENSMUST00000076592
RefSeq Acc Id: XP_036010993   ⟸   XM_036155100
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3612242 AgrOrtholog
Ensembl Genes ENSMUSG00000047220 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000075898 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000076592 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro IHO1 UniProtKB/Swiss-Prot
KEGG Report mmu:434438 UniProtKB/Swiss-Prot
MGD MGI:3612242 ENTREZGENE
NCBI Gene 434438 ENTREZGENE
PANTHER PTHR35662 UniProtKB/Swiss-Prot
Pfam IHO1 UniProtKB/Swiss-Prot
PhenoGen Iho1 PhenoGen
UniGene Mm.425598 ENTREZGENE
UniProt IHO1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-04-07 Iho1  interactor of HORMAD1 1  Ccdc36  coiled-coil domain containing 36  Symbol and/or name change 5135510 APPROVED