Alkal1 (ALK and LTK ligand 1) - Rat Genome Database

Name: Alkal1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Alkal1 (ALK and LTK ligand 1) Mus musculus

Analyze

Symbol:

Alkal1

Name:

ALK and LTK ligand 1

RGD ID:

1621850

MGI Page

MGI

Description:

Predicted to enable protein tyrosine kinase activator activity and signaling receptor binding activity. Predicted to be involved in positive regulation of MAPK cascade; positive regulation of neuron projection development; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. Orthologous to human ALKAL1 (ALK and LTK ligand 1).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

AUG-beta; Augbeta; augmentor beta; EG620393; Fam15; Fam150a; family with sequence similarity 150, member A; hypothetical protein LOC620393; uncharacterized protein LOC620393

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ALKAL1 (ALK and LTK ligand 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Rattus norvegicus (Norway rat):	Alkal1 (ALK and LTK ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ALKAL1 (ALK and LTK ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ALKAL1 (ALK and LTK ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Alkal1 (ALK and LTK ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ALKAL1 (ALK and LTK ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ALKAL1 (ALK and LTK ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Alkal1 (ALK and LTK ligand 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ALKAL2 (ALK and LTK ligand 2)	HGNC	OrthoDB
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Alkal1 (ALK and LTK ligand 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ALKAL1 (ALK and LTK ligand 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	alkal1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	alkal1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	6,429,555 - 6,464,955 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	6,429,442 - 6,464,955 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	6,359,331 - 6,394,731 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	6,359,218 - 6,394,731 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	6,349,134 - 6,384,812 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	6,349,134 - 6,384,812 (+)	NCBI		MGSCv36	mm8
Celera	1	6,345,912 - 6,381,049 (+)	NCBI		Celera
Cytogenetic Map	1	A1	NCBI
cM Map	1	1.89	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

amiodarone (ISO)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

carbon nanotube (EXP)

epoxiconazole (EXP)

fonofos (ISO)

fulvestrant (ISO)

manganese(II) chloride (ISO)

ozone (EXP)

paracetamol (ISO)

parathion (ISO)

terbufos (ISO)

tetraphene (EXP)

titanium dioxide (EXP)

tremolite asbestos (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell surface receptor protein tyrosine kinase signaling pathway (ISO)

positive regulation of ERK1 and ERK2 cascade (IBA,ISO)

positive regulation of ERK5 cascade (IBA,ISO)

positive regulation of neuron projection development (ISO)

Cellular Component

cellular_component (ND)

extracellular region (IEA)

extracellular space (ISO)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

cytokine activity (ISO)

protein binding (ISO)

receptor signaling protein tyrosine kinase activator activity (IBA,ISO)

receptor tyrosine kinase binding (IBA,ISO)

transmembrane receptor protein tyrosine kinase activator activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12520002	PMID:16141072	PMID:16141073	PMID:20562862	PMID:21873635	PMID:25331893	PMID:35412887

Genomics

Comparative Map Data

Alkal1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	6,429,555 - 6,464,955 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	6,429,442 - 6,464,955 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	6,359,331 - 6,394,731 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	6,359,218 - 6,394,731 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	6,349,134 - 6,384,812 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	6,349,134 - 6,384,812 (+)	NCBI		MGSCv36	mm8
Celera	1	6,345,912 - 6,381,049 (+)	NCBI		Celera
Cytogenetic Map	1	A1	NCBI
cM Map	1	1.89	NCBI

ALKAL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	52,534,037 - 52,565,430 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	52,534,037 - 52,565,430 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	53,446,597 - 53,477,990 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	53,609,251 - 53,640,574 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	49,436,928 - 49,468,353 (-)	NCBI		Celera
Cytogenetic Map	8	q11.23	NCBI
HuRef	8	48,914,390 - 48,945,583 (-)	NCBI		HuRef
CHM1_1	8	53,498,972 - 53,530,389 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	52,910,076 - 52,941,473 (-)	NCBI		T2T-CHM13v2.0

Alkal1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	17,806,601 - 17,836,789 (-)	NCBI		GRCr8
mRatBN7.2	5	13,019,729 - 13,049,913 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	13,019,429 - 13,049,948 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	15,189,353 - 15,219,628 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	16,821,441 - 16,851,558 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	16,524,040 - 16,554,319 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	12,896,136 - 12,925,571 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	12,896,558 - 12,925,571 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	17,668,931 - 17,697,947 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	13,167,027 - 13,196,791 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	12,433,940 - 12,464,105 (-)	NCBI		Celera
Cytogenetic Map	5	q12	NCBI

ALKAL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	68,168,573 - 68,200,225 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	43,893,772 - 43,925,387 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	48,957,611 - 48,989,157 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	46,341,310 - 46,372,344 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	46,341,310 - 46,372,344 (-)	Ensembl	panpan1.1		panPan2

ALKAL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	4,375,877 - 4,395,708 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	29	4,815,737 - 4,835,644 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	29	4,441,691 - 4,461,589 (-)	NCBI		ROS_Cfam_1.0

Alkal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	75,186,430 - 75,209,168 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936590	376,301 - 396,488 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936590	376,301 - 396,488 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALKAL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	77,673,244 - 77,683,074 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	77,673,200 - 77,682,697 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ALKAL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	48,641,163 - 48,672,392 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	48,645,771 - 48,669,954 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	93,330,791 - 93,359,214 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Alkal1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	2,914,937 - 2,941,798 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	2,915,115 - 2,941,401 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Alkal1
1009 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	90
Count of miRNA genes:	84
Interacting mature miRNAs:	84
Transcripts:	ENSMUST00000133144
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10412226	Alpq4_m	alcohol preference QTL 4 (mouse)			Not determined		1	1	22976684	Mouse
1301891	Alcp25_m	alcohol preference locus 25 (mouse)			Not determined		1	1	25203185	Mouse
1300834	Cia20_m	collagen induced arthritis 20 (mouse)			Not determined		1	1	25203185	Mouse
1301482	Morph1_m	morphine antinociception 1 (mouse)			Not determined		1	1	30367747	Mouse
1301275	Sle10_m	systematic lupus erythematosus susceptibility 10 (mouse)			Not determined		1	2882194	36882352	Mouse
1301370	Adip1_m	adiposity 1 (mouse)			Not determined		1	2882194	36882352	Mouse
13824984	Twq5_m	testis weight QTL 5 (mouse)					1	3069992	184732197	Mouse
15092044	Wtgrme1_m	week ten growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092046	Wngrme1_m	week nine growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092048	Wsigrme1_m	week six growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092050	Wsegrme1_m	week seven growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092051	Wegrme1_m	week eight growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
15092055	Lgrme1_m	late growth rate, maternal effect 1 (mouse)					1	3280142	37782236	Mouse
11039528	Ccc3_m	colitis susceptibility in the Collaborative Cross 3 (mouse)					1	3680142	195051546	Mouse
1301471	Obq2_m	obesity QTL 2 (mouse)			Not determined		1	3941620	37941887	Mouse
10043970	Obq23_m	obesity QTL 23 (mouse)			Not determined		1	5012665	39012665	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001195732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC139064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK087278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000133144 ⟹ ENSMUSP00000137420

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	6,429,442 - 6,464,955 (+)	Ensembl
GRCm38.p6 Ensembl	1	6,359,218 - 6,394,731 (+)	Ensembl

RefSeq Acc Id:

NM_001195732 ⟹ NP_001182661

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	6,429,555 - 6,464,955 (+)	NCBI
GRCm38	1	6,359,331 - 6,394,731 (+)	NCBI
Celera	1	6,345,912 - 6,381,049 (+)	ENTREZGENE
cM Map	1		ENTREZGENE

Sequence:

show sequence

ATGTGGCTCACTAAGCCCAGCACCCCGGTGTCCGCACTGCTGCTGCTGGCGCTGGCTTTGTCCC
CGCCTGGGACTCAGGGGCGGCCCCAGAGAAGCTTGGCAGCGCGTGTCGCTGAGCTCAGGCCAGA
GCTCTTCCTCCCTGTGACAGGGACTCGCCTGCCTCCCAGAGCCTCCCGGAGCACAGAAATATTC
CCAAGAGACTTGACATTGAAAGACAAATTCATAAAGCATTTCACAGGGCCTGTCACATTTTCAG
CTGAATGTAGCAAACACTTCCATCGACTTTATCACAATACCCGGGATTGCTCGACGCCAGCTTA
TTATAAAAGATGTGCTAGATTGCTGACAAGATTAGCTGTGAGTCCACTATGCTCCCAGACCTAG
GAAACTTGTGCTACATTTCATAAGAAGCAAATATAATTTGAAGAAAAAGTGCCTGGAATCATAT
TTAATATAAAAAATGGACATGTTTAGTTTTGTATGAACTTGCATGAAGTAACTTCTCAGGAGAA
ACCTATGAGTGGCTACAGGAAGAGGACGCTTCCCTGGCTTACGTTATGGACACAAAAAGTTAGA
GTATTTTTTAAGATCACATATTGTAAATAGAATATTTAAAACTGTGCCTTATTTTTGCTAGGAA
TATTATTTTTATATGGTTAATATTGTATGGTAAATATTTAATTATGTTAATTGTATCTCAGTAG
TAGTGAAAAAATAACTATTGCATATAATTTTAGTGATGTGTTTGTCAGATATTGTGTTCAGTTT
TTTAATTCTTATTTAATATTTAAAAGCTTTTATTAATAATTTTCTGTCCTTATTTGCATTAATT
TGAACTGTGAATTTTATTAAAACAGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001182661	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000137420
	ENSMUSP00000137420.2
GenBank Protein	J3QPP8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001182661 ⟸ NM_001195732
- Peptide Label:	precursor
- UniProtKB:	J3QPP8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWLTKPSTPVSALLLLALALSPPGTQGRPQRSLAARVAELRPELFLPVTGTRLPPRASRSTEIF PRDLTLKDKFIKHFTGPVTFSAECSKHFHRLYHNTRDCSTPAYYKRCARLLTRLAVSPLCSQT hide sequence

RefSeq Acc Id:

ENSMUSP00000137420 ⟸ ENSMUST00000133144

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-J3QPP8-F1-model_v2	AlphaFold	J3QPP8	1-127	view protein structure

Promoters

RGD ID:

6818021

Promoter ID:

MM_KWN:43

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Lung, MEF_B4, MEF_B6

Transcripts:

AK087278_FAM150A, LINCRNA_1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	1	6,349,346 - 6,349,846 (+)	MPROMDB

RGD ID:

6873126

Promoter ID:

EPDNEW_M14

Type:

single initiation site

Name:

Alkal1_1

Description:

Mus musculus ALK and LTK ligand 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	1	6,359,287 - 6,359,347	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3645495	AgrOrtholog
Ensembl Genes	ENSMUSG00000087247	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000133144	ENTREZGENE
	ENSMUST00000133144.4	UniProtKB/Swiss-Prot
InterPro	FAM150A/B	UniProtKB/Swiss-Prot
KEGG Report	mmu:620393	UniProtKB/Swiss-Prot
MGD	MGI:3645495	ENTREZGENE
NCBI Gene	620393	ENTREZGENE
PANTHER	ALK AND LTK LIGAND 1	UniProtKB/Swiss-Prot
	PTHR28676	UniProtKB/Swiss-Prot
Pfam	FAM150	UniProtKB/Swiss-Prot
PhenoGen	Alkal1	PhenoGen
UniProt	ALKL1_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-06-06	Alkal1	ALK and LTK ligand 1	Fam150a	family with sequence similarity 150, member A	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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