Gm6377 (predicted gene 6377) - Rat Genome Database

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Gene: Gm6377 (predicted gene 6377) Mus musculus
Analyze
No known orthologs.
Symbol: Gm6377
Name: predicted gene 6377
RGD ID: 1621831
MGI Page MGI
Description: Predicted to be involved in regulation of lysosomal lumen pH.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG622976; hypothetical protein LOC622976; RP23-252O5.3; uncharacterized protein LOC622976
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X108,240,362 - 108,244,051 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX108,240,362 - 108,244,045 (+)EnsemblGRCm39 Ensembl
GRCm38X109,196,756 - 109,200,445 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX109,196,756 - 109,200,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X106,392,095 - 106,395,784 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X105,399,508 - 105,403,157 (+)NCBIMGSCv36mm8
CeleraX96,021,416 - 96,025,105 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX47.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635   PMID:31950438  


Genomics

Variants

.
Variants in Gm6377
77 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:455
Count of miRNA genes:331
Interacting mature miRNAs:373
Transcripts:ENSMUST00000060013, ENSMUST00000139259
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse
1357500Mdmsc6_mmodifier of muscularity 6 (mouse)Not determinedX75306671109306758Mouse
11075102Modc2_mmodifier of Odc2 (mouse)X80189914114190059Mouse
4141803Lmr30_mleishmaniasis resistance 30 (mouse)Not determined85062606119062720Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000060013   ⟹   ENSMUSP00000049931
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX108,240,364 - 108,244,045 (+)Ensembl
GRCm38.p6 EnsemblX109,196,758 - 109,200,439 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139259   ⟹   ENSMUSP00000118524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX108,240,362 - 108,242,184 (+)Ensembl
GRCm38.p6 EnsemblX109,196,756 - 109,198,578 (+)Ensembl
RefSeq Acc Id: NM_001037917   ⟹   NP_001033006
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X108,240,362 - 108,244,051 (+)NCBI
GRCm38X109,196,756 - 109,200,445 (+)NCBI
MGSCv37X106,392,095 - 106,395,784 (+)RGD
CeleraX96,021,416 - 96,025,105 (+)RGD
cM MapX ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001033006 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI47432 (Get FASTA)   NCBI Sequence Viewer  
  AAI47433 (Get FASTA)   NCBI Sequence Viewer  
  BAC37866 (Get FASTA)   NCBI Sequence Viewer  
  BAE23747 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000049931
  ENSMUSP00000049931.4
  ENSMUSP00000118524.2
Reference Protein Sequences
RefSeq Acc Id: NP_001033006   ⟸   NM_001037917
- UniProtKB: Q8BHV4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000118524   ⟸   ENSMUST00000139259
RefSeq Acc Id: ENSMUSP00000049931   ⟸   ENSMUST00000060013

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BHV4-F1-model_v2 AlphaFold Q8BHV4 1-303 view protein structure

Promoters
RGD ID:6845787
Promoter ID:MM_KWN:61589
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Spleen
Transcripts:NM_001037917,   OTTMUST00000044289
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X106,391,899 - 106,392,399 (+)MPROMDB
RGD ID:13681250
Promoter ID:EPDNEW_M24774
Type:initiation region
Name:Gm6377_1
Description:Mus musculus predicted gene 6377 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X109,196,789 - 109,196,849EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3647255 AgrOrtholog
Ensembl Genes ENSMUSG00000048621 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000060013 ENTREZGENE
  ENSMUST00000060013.4 UniProtKB/TrEMBL
  ENSMUST00000139259.2 UniProtKB/TrEMBL
InterPro DUF4569 UniProtKB/TrEMBL
KEGG Report mmu:622976 UniProtKB/TrEMBL
MGD MGI:3647255 ENTREZGENE
NCBI Gene 622976 ENTREZGENE
PANTHER GENE 6377-RELATED UniProtKB/TrEMBL
  PTHR14889 UniProtKB/TrEMBL
Pfam DUF4569 UniProtKB/TrEMBL
PhenoGen Gm6377 PhenoGen
UniProt A2ALN9_MOUSE UniProtKB/TrEMBL
  Q8BHV4 ENTREZGENE, UniProtKB/TrEMBL