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Gene: Pax5 (paired box 5) Mus musculus
Symbol: Pax5
Name: paired box 5
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including animal organ development; negative regulation of histone H3-K9 methylation; and regulation of transcription by RNA polymerase II. Localizes to the nucleus. Human ortholog(s) of this gene implicated in precursor lymphoblastic lymphoma/leukemia. Is expressed in several structures, including central nervous system; future brain; liver; thymus; and urinary system. Orthologous to human PAX5 (paired box 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell-specific transcription factor; BSAP; EBB-1; KLP; paired box gene 5; paired box protein Pax-5; Pax-5; Pax5 variant 1; Pax5 variant 2
Homo sapiens (human) : PAX5 (paired box 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pax5 (paired box 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pax5 (paired box 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PAX5 (paired box 5)
Canis lupus familiaris (dog) : PAX5 (paired box 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pax5 (paired box 5)
Sus scrofa (pig) : PAX5 (paired box 5)
Chlorocebus sabaeus (African green monkey) : PAX5 (paired box 5)
Heterocephalus glaber (naked mole-rat) : Pax5 (paired box 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl444,524,757 - 44,710,487 (-)Ensembl
GRCm38444,524,748 - 44,710,694 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37444,544,378 - 44,723,312 (-)NCBIGRCm37mm9NCBIm37
MGSCv36444,552,606 - 44,731,540 (-)NCBImm8
Celera444,550,836 - 44,729,998 (-)NCBICelera
Cytogenetic Map4 B1NCBI
cM Map423.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Pax5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1621602
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.