Gipc1 (GIPC PDZ domain containing family, member 1) - Rat Genome Database
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Gene: Gipc1 (GIPC PDZ domain containing family, member 1) Mus musculus
Analyze
Symbol: Gipc1
Name: GIPC PDZ domain containing family, member 1
RGD ID: 1621539
MGI Page MGI
Description: Is expressed in several structures, including brain; future brain; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human GIPC1 (GIPC PDZ domain containing family member 1); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GAIP C-terminus-interacting protein; GIPC; Glut1; Glut1CIP; neurophilin1-IP; PDZ domain-containing protein GIPC1; regulator of G-protein signaling 19 interacting protein 1; RGS-GAIP interacting protein GIPC; RGS-GAIP-interacting protein; Rgs1; RGS19-interacting protein 1; Rgs19ip1; semaF cytoplasmic domain associated protein; semaF cytoplasmic domain-associated protein 1; Semc; SEMCAP-1; Semcap1; syne; synectin; Tax; Tax interacting protein, clone 2; TaxIP2; TIP; TIP-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,376,037 - 84,391,418 (+)NCBIGRCm39mm39
GRCm39 Ensembl884,379,306 - 84,391,323 (+)Ensembl
GRCm38883,649,408 - 83,664,789 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,652,677 - 83,664,694 (+)EnsemblGRCm38mm10GRCm38
MGSCv37886,176,577 - 86,188,688 (+)NCBIGRCm37mm9NCBIm37
MGSCv36886,542,783 - 86,554,894 (+)NCBImm8
Celera887,943,499 - 87,955,588 (+)NCBICelera
Cytogenetic Map8C2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9770488   PMID:10318831   PMID:10349636   PMID:10414980   PMID:10827173   PMID:10911369   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11342430   PMID:11546783  
PMID:11751850   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15527962   PMID:15782199   PMID:15975910   PMID:15978582   PMID:16141072  
PMID:16141073   PMID:16467373   PMID:16602821   PMID:16740480   PMID:16819522   PMID:16908842   PMID:16940428   PMID:17576142   PMID:17967808   PMID:18723443   PMID:18775991   PMID:18799693  
PMID:18824598   PMID:19235722   PMID:19581409   PMID:20434959   PMID:20634288   PMID:21543326   PMID:21677750   PMID:21871877   PMID:22991442   PMID:23884936   PMID:23897694   PMID:24498314  
PMID:26013465   PMID:26265212   PMID:28190767   PMID:28224988   PMID:28289053   PMID:28537552   PMID:28671696   PMID:29581031   PMID:32325033  


Genomics

Comparative Map Data
Gipc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,376,037 - 84,391,418 (+)NCBIGRCm39mm39
GRCm39 Ensembl884,379,306 - 84,391,323 (+)Ensembl
GRCm38883,649,408 - 83,664,789 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,652,677 - 83,664,694 (+)EnsemblGRCm38mm10GRCm38
MGSCv37886,176,577 - 86,188,688 (+)NCBIGRCm37mm9NCBIm37
MGSCv36886,542,783 - 86,554,894 (+)NCBImm8
Celera887,943,499 - 87,955,588 (+)NCBICelera
Cytogenetic Map8C2NCBI
GIPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1914,477,760 - 14,496,149 (-)EnsemblGRCh38hg38GRCh38
GRCh381914,477,761 - 14,496,133 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371914,588,574 - 14,606,939 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,449,571 - 14,467,944 (-)NCBINCBI36hg18NCBI36
Build 341914,449,571 - 14,467,944NCBI
Celera1914,482,692 - 14,501,043 (-)NCBI
Cytogenetic Map19p13.12NCBI
HuRef1914,158,686 - 14,177,001 (-)NCBIHuRef
CHM1_11914,588,560 - 14,606,924 (-)NCBICHM1_1
Gipc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21924,474,291 - 24,487,083 (-)NCBI
Rnor_6.0 Ensembl1924,786,628 - 24,798,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01924,786,604 - 24,798,231 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01935,765,772 - 35,778,495 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41926,165,658 - 26,177,206 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11926,170,483 - 26,174,300 (-)NCBI
Celera1924,018,366 - 24,029,872 (-)NCBICelera
Cytogenetic Map19q11NCBI
Gipc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541533,067,689 - 33,074,730 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541533,067,689 - 33,077,749 (-)NCBIChiLan1.0ChiLan1.0
GIPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11914,884,529 - 14,897,247 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1914,885,185 - 14,889,701 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01914,041,192 - 14,059,402 (-)NCBIMhudiblu_PPA_v0panPan3
GIPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2048,150,498 - 48,157,191 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12048,144,076 - 48,155,069 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gipc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366593,019,829 - 3,030,280 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GIPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl264,780,442 - 64,798,783 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1264,780,447 - 64,794,922 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,158,635 - 65,174,711 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GIPC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,136,647 - 13,155,259 (-)NCBI
ChlSab1.1 Ensembl613,136,624 - 13,142,002 (-)Ensembl


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88006677589014359Mouse
10755530Wbc2_mwhite blood cell count 2 (mouse)881092664115092664Mouse
10755519Wbc1_mwhite blood cell count 1 (mouse)881619151115619151Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:259
Count of miRNA genes:212
Interacting mature miRNAs:226
Transcripts:ENSMUST00000019577
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_018771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC164432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF061263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF089818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF104358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000019577   ⟹   ENSMUSP00000019577
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl883,652,677 - 83,664,694 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211985   ⟹   ENSMUSP00000148847
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl883,652,686 - 83,662,366 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212463   ⟹   ENSMUSP00000148824
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl883,652,698 - 83,661,187 (+)Ensembl
RefSeq Acc Id: NM_018771   ⟹   NP_061241
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39884,379,307 - 84,391,418 (+)NCBI
GRCm38883,652,678 - 83,664,789 (+)ENTREZGENE
MGSCv37886,176,577 - 86,188,688 (+)RGD
Celera887,943,499 - 87,955,588 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030243739   ⟹   XP_030099599
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39884,376,037 - 84,391,313 (+)NCBI
GRCm38883,649,408 - 83,664,682 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_061241   ⟸   NM_018771
- UniProtKB: Q9Z0G0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030099599   ⟸   XM_030243739
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000148847   ⟸   ENSMUST00000211985
RefSeq Acc Id: ENSMUSP00000148824   ⟸   ENSMUST00000212463
RefSeq Acc Id: ENSMUSP00000019577   ⟸   ENSMUST00000019577
Protein Domains
PDZ

Promoters
RGD ID:8667611
Promoter ID:EPDNEW_M11837
Type:initiation region
Name:Gipc1_1
Description:Mus musculus GIPC PDZ domain containing family, member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38883,652,701 - 83,652,761EPDNEW
RGD ID:6843188
Promoter ID:MM_KWN:55011
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_018771
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36886,176,131 - 86,176,687 (+)MPROMDB
RGD ID:6848292
Promoter ID:MM_ACW:48174
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:GIPC1.CSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36886,188,086 - 86,188,586 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1926252 AgrOrtholog
Ensembl Genes ENSMUSG00000019433 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000019577 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148824 UniProtKB/TrEMBL
  ENSMUSP00000148847 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000019577 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000211985 UniProtKB/TrEMBL
  ENSMUST00000212463 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GIPC1/2/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67903 UniProtKB/Swiss-Prot
MGD MGI:1926252 ENTREZGENE
NCBI Gene 67903 ENTREZGENE
PANTHER PTHR12259 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gipc1 PhenoGen
PIRSF UCP038083_GIPC UniProtKB/Swiss-Prot
PROSITE PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1D5RML2_MOUSE UniProtKB/TrEMBL
  A0A1D5RMN2_MOUSE UniProtKB/TrEMBL
  GIPC1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE