Pramel3a (PRAME like 3A) - Rat Genome Database

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Gene: Pramel3a (PRAME like 3A) Mus musculus
Analyze
No known orthologs.
Symbol: Pramel3a
Name: PRAME like 3A
RGD ID: 1621431
MGI Page MGI
Description: Predicted to be active in cytoplasm. Is expressed in germ cell of testis; ovary; primary sex cord; and testis.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: PRAME like 3; Pramel3; preferentially expressed antigen in melanoma-like 3
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X134,203,039 - 134,213,385 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX134,203,056 - 134,213,401 (+)EnsemblGRCm39 Ensembl
GRCm38X135,302,289 - 135,312,636 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX135,302,307 - 135,312,652 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X131,836,855 - 131,847,175 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X130,648,680 - 130,659,000 (+)NCBIMGSCv36mm8
CeleraX118,818,082 - 118,828,060 (+)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX56.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
folic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11279525   PMID:12466851   PMID:16118233   PMID:17660561   PMID:18287559   PMID:21079677   PMID:21267068   PMID:21873635   PMID:23677977   PMID:25634095  


Genomics

Variants

.
Variants in Pramel3a
240 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1277
Count of miRNA genes:535
Interacting mature miRNAs:638
Transcripts:ENSMUST00000113176, ENSMUST00000118821
Prediction methods:Miranda, Pita
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX120993165160213038Mouse
25314309Syncl5_msynaptonemal complex length 5 (mouse)X121909697152582996Mouse
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX125685149159685269Mouse
13824981Svwq2_mseminal vesicle weight QTL 2 (mouse)X128900749153782996Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX133540040165298595Mouse

Markers in Region
G65331  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXF1UniSTS
cM MapX UniSTS
G65782  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXF1UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000113176   ⟹   ENSMUSP00000108801
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX134,203,065 - 134,213,385 (+)Ensembl
GRCm38.p6 EnsemblX135,302,316 - 135,312,636 (+)Ensembl
RefSeq Acc Id: ENSMUST00000118821   ⟹   ENSMUSP00000112761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX134,203,056 - 134,213,401 (+)Ensembl
GRCm38.p6 EnsemblX135,302,307 - 135,312,652 (+)Ensembl
RefSeq Acc Id: NM_031390   ⟹   NP_113567
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X134,203,065 - 134,213,385 (+)NCBI
GRCm38X135,302,316 - 135,312,636 (+)NCBI
MGSCv37X131,836,855 - 131,847,175 (+)RGD
CeleraX118,721,511 - 118,725,989 (-)ENTREZGENE
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006528634   ⟹   XP_006528697
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X134,203,039 - 134,212,841 (+)NCBI
GRCm38X135,302,289 - 135,312,091 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_113567 (Get FASTA)   NCBI Sequence Viewer  
  XP_006528697 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF88139 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000112761
  ENSMUSP00000112761.3
RefSeq Acc Id: NP_113567   ⟸   NM_031390
- UniProtKB: Q99M97 (UniProtKB/TrEMBL),   Q8C0W2 (UniProtKB/TrEMBL),   A2AHA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006528697   ⟸   XM_006528634
- Peptide Label: isoform X1
- UniProtKB: Q8C0W2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000112761   ⟸   ENSMUST00000118821
RefSeq Acc Id: ENSMUSP00000108801   ⟸   ENSMUST00000113176

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2AHA7-F1-model_v2 AlphaFold A2AHA7 1-463 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1890657 AgrOrtholog
Ensembl Genes ENSMUSG00000067360 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000118821 ENTREZGENE
  ENSMUST00000118821.8 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
KEGG Report mmu:83565 UniProtKB/TrEMBL
MGD MGI:1890657 ENTREZGENE
NCBI Gene 83565 ENTREZGENE
PANTHER EXPRESSED SEQUENCE AV320801-RELATED UniProtKB/TrEMBL
  SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 UniProtKB/TrEMBL
PhenoGen Pramel3a PhenoGen
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A2AHA7 ENTREZGENE
  Q8C0W2 ENTREZGENE
  Q99M97 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A2AHA7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-08 Pramel3a  PRAME like 3A  Pramel3  PRAME like 3  Symbol and/or name updated 27372883 PROVISIONAL
2020-06-19 Pramel3  PRAME like 3  Pramel3  preferentially expressed antigen in melanoma-like 3  Symbol and/or name change 5135510 APPROVED