Zfp382 (zinc finger protein 382) - Rat Genome Database

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Gene: Zfp382 (zinc finger protein 382) Mus musculus
Analyze
Symbol: Zfp382
Name: zinc finger protein 382
RGD ID: 1621326
MGI Page MGI
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF382 (zinc finger protein 382).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4930428B01R; 4930428B01Rik; 5930415A09Rik; hypothetical protein LOC73854; KRAB/zinc finger suppressor protein 1; KS1; multiple zinc finger and krueppel-associated box protein KS1; RIKEN cDNA 4930428B01 gene; uncharacterized protein LOC73854; Znf382
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39729,821,255 - 29,840,180 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl729,821,367 - 29,834,375 (+)EnsemblGRCm39 Ensembl
GRCm38730,121,833 - 30,140,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,121,942 - 30,134,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv37730,906,967 - 30,920,051 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36729,830,708 - 29,843,792 (+)NCBIMGSCv36mm8
Celera724,724,357 - 24,738,559 (+)NCBICelera
Cytogenetic Map7B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Large-scale characterization of DNA methylation changes in human gastric carcinomas with and without metastasis. Liu Z, etal., Clin Cancer Res. 2014 Sep 1;20(17):4598-612. doi: 10.1158/1078-0432.CCR-13-3380. Epub 2014 Jul 9.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12040188   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15618518   PMID:16141072   PMID:16141073   PMID:18287559  
PMID:21677750   PMID:21873635   PMID:32325033   PMID:34762123  


Genomics

Comparative Map Data
Zfp382
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39729,821,255 - 29,840,180 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl729,821,367 - 29,834,375 (+)EnsemblGRCm39 Ensembl
GRCm38730,121,833 - 30,140,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,121,942 - 30,134,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv37730,906,967 - 30,920,051 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36729,830,708 - 29,843,792 (+)NCBIMGSCv36mm8
Celera724,724,357 - 24,738,559 (+)NCBICelera
Cytogenetic Map7B1NCBI
ZNF382
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381936,605,313 - 36,634,114 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1936,604,817 - 36,634,114 (+)EnsemblGRCh38hg38GRCh38
GRCh371937,096,215 - 37,125,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361941,788,061 - 41,811,339 (+)NCBINCBI36Build 36hg18NCBI36
Build 341941,788,060 - 41,811,338NCBI
Celera1933,880,792 - 33,904,099 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1933,564,157 - 33,587,507 (+)NCBIHuRef
CHM1_11937,096,795 - 37,120,088 (+)NCBICHM1_1
T2T-CHM13v2.01939,280,598 - 39,309,416 (+)NCBIT2T-CHM13v2.0
Zfp382
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,504,344 - 94,528,316 (+)NCBIGRCr8
mRatBN7.2185,377,614 - 85,400,832 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,377,484 - 85,399,667 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx190,795,435 - 90,818,893 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,264,250 - 99,287,453 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0192,553,703 - 92,577,163 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0188,582,641 - 88,603,219 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,581,206 - 88,605,697 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0189,743,564 - 89,763,846 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,175,213 - 85,184,576 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1185,253,323 - 85,262,683 (+)NCBI
Celera179,753,982 - 79,774,540 (+)NCBICelera
Cytogenetic Map1q21NCBI
Znf382
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554682,278,594 - 2,299,493 (+)NCBIChiLan1.0ChiLan1.0
ZNF382
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22042,747,013 - 42,775,910 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11944,631,787 - 44,660,680 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01933,566,071 - 33,594,961 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11943,176,836 - 43,199,770 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1943,176,591 - 43,199,760 (-)Ensemblpanpan1.1panPan2
ZNF382
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,226,916 - 116,278,163 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,252,743 - 116,277,633 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1115,633,164 - 115,684,983 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01116,828,932 - 116,880,949 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1116,829,615 - 116,880,948 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11116,398,704 - 116,450,707 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,017,627 - 116,069,916 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,069,239 - 117,121,249 (+)NCBIUU_Cfam_GSD_1.0
Znf382
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934911,571,859 - 11,594,975 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936922347,898 - 362,345 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936922348,997 - 362,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF382
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,777,393 - 45,812,338 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1645,776,183 - 45,795,964 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2641,220,163 - 41,236,080 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF382
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1631,429,216 - 31,482,534 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660739,233,325 - 9,288,334 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf382
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479410,573,286 - 10,590,943 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479410,577,110 - 10,646,192 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Zfp382
824 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:460
Count of miRNA genes:348
Interacting mature miRNAs:391
Transcripts:ENSMUST00000098596, ENSMUST00000153792, ENSMUST00000156543
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
7394747asp3_maudiogenic seizure prone 3 (mouse)Not determined72730579836842367Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000098596   ⟹   ENSMUSP00000096196
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl729,821,367 - 29,834,375 (+)Ensembl
GRCm38.p6 Ensembl730,121,942 - 30,134,950 (+)Ensembl
RefSeq Acc Id: ENSMUST00000153792   ⟹   ENSMUSP00000123508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl729,821,395 - 29,830,241 (+)Ensembl
GRCm38.p6 Ensembl730,121,970 - 30,130,816 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl729,825,040 - 29,832,970 (+)Ensembl
GRCm38.p6 Ensembl730,125,615 - 30,133,545 (+)Ensembl
RefSeq Acc Id: NM_001081007   ⟹   NP_001074476
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39729,821,357 - 29,840,180 (+)NCBI
GRCm38730,121,932 - 30,140,755 (+)NCBI
MGSCv37730,906,967 - 30,920,051 (+)RGD
Celera724,724,357 - 24,738,559 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001362158   ⟹   NP_001349087
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39729,821,357 - 29,840,180 (+)NCBI
GRCm38730,121,932 - 30,140,755 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001362159   ⟹   NP_001349088
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39729,821,357 - 29,840,180 (+)NCBI
GRCm38730,121,932 - 30,140,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322166   ⟹   XP_017177655
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39729,821,255 - 29,840,179 (+)NCBI
GRCm38730,121,833 - 30,140,758 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001074476   ⟸   NM_001081007
- Peptide Label: isoform 1
- UniProtKB: Q3UYY9 (UniProtKB/Swiss-Prot),   B2RXC5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017177655   ⟸   XM_017322166
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001349088   ⟸   NM_001362159
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001349087   ⟸   NM_001362158
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000123508   ⟸   ENSMUST00000153792
RefSeq Acc Id: ENSMUSP00000096196   ⟸   ENSMUST00000098596
Protein Domains
KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RXC5-F1-model_v2 AlphaFold B2RXC5 1-579 view protein structure

Promoters
RGD ID:6892574
Promoter ID:EPDNEW_M9738
Type:initiation region
Name:Zfp382_1
Description:Mus musculus zinc finger protein 382 , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38730,121,934 - 30,121,994EPDNEW
RGD ID:6842380
Promoter ID:MM_KWN:49770
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000074312,   OTTMUST00000074314
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36730,906,361 - 30,906,997 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3588204 AgrOrtholog
Ensembl Genes ENSMUSG00000074220 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098596 ENTREZGENE
  ENSMUST00000098596.11 UniProtKB/Swiss-Prot
  ENSMUST00000153792.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot
  Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro KRAB UniProtKB/Swiss-Prot
  KRAB_dom_sf UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report mmu:233060 UniProtKB/Swiss-Prot
MGD MGI:3588204 ENTREZGENE
NCBI Gene 233060 ENTREZGENE
PANTHER KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/Swiss-Prot
  KRAB DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam KRAB UniProtKB/Swiss-Prot
  zf-C2H2 UniProtKB/Swiss-Prot
PhenoGen Zfp382 PhenoGen
PROSITE KRAB UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART KRAB UniProtKB/Swiss-Prot
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot
  SSF57667 UniProtKB/Swiss-Prot
UniProt B2RXC5 ENTREZGENE
  D3YYS3_MOUSE UniProtKB/TrEMBL
  Q3UYY9 ENTREZGENE
  Q9CUP4_MOUSE UniProtKB/TrEMBL
  ZN382_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3UYY9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-10 Zfp382  zinc finger protein 382  4930428B01Rik  RIKEN cDNA 4930428B01 gene  Data merged from RGD:1608722 737654 PROVISIONAL