Zfp868 (zinc finger protein 868) - Rat Genome Database
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Gene: Zfp868 (zinc finger protein 868) Mus musculus
Analyze
No known orthologs.
Symbol: Zfp868
Name: zinc finger protein 868
RGD ID: 1621316
MGI Page MGI
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including blastocyst; early embryo; extraembryonic component; genitourinary system; and limb mesenchyme. Orthologous to human ZNF670 (zinc finger protein 670) and ZNF844 (zinc finger protein 844); INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI449175; AW108241; C530032E20; Kruppel-like zinc finger protein; mszf62
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,063,305 - 70,078,208 (-)NCBIGRCm39mm39
GRCm38869,610,654 - 69,625,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,610,857 - 69,625,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,134,553 - 72,149,447 (-)NCBIGRCm37mm9NCBIm37
MGSCv36872,539,844 - 72,554,501 (-)NCBImm8
Celera872,162,088 - 72,177,012 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9630514   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15618518   PMID:16141072   PMID:16141073  
PMID:18287559   PMID:18799693   PMID:20059953   PMID:21267068   PMID:21873635   PMID:26142281  


Genomics

Position Markers
AI449175  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,610,996 - 69,611,106UniSTSGRCm38
MGSCv37872,134,895 - 72,135,005UniSTSGRCm37
Celera872,162,430 - 72,162,540UniSTS
Cytogenetic Map8B3.3UniSTS
Whitehead/MRC_RH8727.75UniSTS
Whitehead/MRC_RH8725.77UniSTS
UniSTS:235909  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,710,737 - 69,710,937UniSTSGRCm38
GRCm38869,619,424 - 69,619,624UniSTSGRCm38
MGSCv37872,234,636 - 72,234,836UniSTSGRCm37
MGSCv37872,143,323 - 72,143,523UniSTSGRCm37
Celera872,261,998 - 72,262,198UniSTS
Celera872,170,888 - 72,171,088UniSTS
Cytogenetic Map8B3.3UniSTS
UniSTS:235912  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,610,996 - 69,611,301UniSTSGRCm38
MGSCv37872,134,895 - 72,135,200UniSTSGRCm37
Celera872,162,430 - 72,162,735UniSTS
Cytogenetic Map8B3.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:352
Count of miRNA genes:271
Interacting mature miRNAs:289
Transcripts:ENSMUST00000074982, ENSMUST00000121886, ENSMUST00000140522, ENSMUST00000150118
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001045553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011242291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011242292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011242293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB010369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC157564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC166750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI449175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY023781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000074982   ⟹   ENSMUSP00000074510
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,611,414 - 69,619,352 (-)Ensembl
RefSeq Acc Id: ENSMUST00000121886   ⟹   ENSMUSP00000113952
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,610,857 - 69,625,548 (-)Ensembl
RefSeq Acc Id: ENSMUST00000140522
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,618,869 - 69,625,545 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150118
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,612,420 - 69,614,063 (-)Ensembl
RefSeq Acc Id: NM_001045553   ⟹   NP_001039018
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,063,305 - 70,077,826 (-)NCBI
GRCm38869,610,654 - 69,625,175 (-)NCBI
MGSCv37872,134,553 - 72,149,447 (-)RGD
Celera872,162,088 - 72,177,012 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_172754   ⟹   NP_766342
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,063,305 - 70,078,199 (-)NCBI
GRCm38869,610,654 - 69,625,548 (-)NCBI
MGSCv37872,134,553 - 72,149,447 (-)RGD
Celera872,162,088 - 72,177,012 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011242291   ⟹   XP_011240593
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,063,305 - 70,078,208 (-)NCBI
GRCm38869,610,654 - 69,625,557 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242292   ⟹   XP_011240594
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,063,305 - 70,078,072 (-)NCBI
GRCm38869,610,654 - 69,625,423 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242293   ⟹   XP_011240595
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,063,305 - 70,078,203 (-)NCBI
GRCm38869,610,654 - 69,625,553 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243457   ⟹   XP_030099317
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,063,305 - 70,078,073 (-)NCBI
GRCm38869,610,654 - 69,625,424 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243459   ⟹   XP_030099319
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,063,305 - 70,066,100 (-)NCBI
GRCm38869,610,654 - 69,613,876 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_766342   ⟸   NM_172754
- UniProtKB: Q3UTQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001039018   ⟸   NM_001045553
- UniProtKB: Q3UTQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011240593   ⟸   XM_011242291
- Peptide Label: isoform X1
- UniProtKB: Q3UTQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011240595   ⟸   XM_011242293
- Peptide Label: isoform X1
- UniProtKB: Q3UTQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011240594   ⟸   XM_011242292
- Peptide Label: isoform X1
- UniProtKB: Q3UTQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030099317   ⟸   XM_030243457
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030099319   ⟸   XM_030243459
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000074510   ⟸   ENSMUST00000074982
RefSeq Acc Id: ENSMUSP00000113952   ⟸   ENSMUST00000121886
Protein Domains
C2H2-type   KRAB

Promoters
RGD ID:8667231
Promoter ID:EPDNEW_M11647
Type:initiation region
Name:Zfp868_1
Description:Mus musculus zinc finger protein 868 , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38869,625,549 - 69,625,609EPDNEW
RGD ID:6842686
Promoter ID:MM_KWN:54628
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001045553,   NM_172754,   OTTMUST00000076985
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,149,051 - 72,149,607 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2142546 AgrOrtholog
Ensembl Genes ENSMUSG00000060427 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000074510 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000113952 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074982 UniProtKB/TrEMBL
  ENSMUST00000121886 ENTREZGENE, UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:234362 UniProtKB/TrEMBL
MGD MGI:2142546 ENTREZGENE
NCBI Gene 234362 ENTREZGENE
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp868 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniGene Mm.458487 ENTREZGENE
UniProt O88263_MOUSE UniProtKB/TrEMBL
  Q3UTQ6 ENTREZGENE, UniProtKB/TrEMBL
  Q8BUQ2_MOUSE UniProtKB/TrEMBL
  Q91Z24_MOUSE UniProtKB/TrEMBL