Yjefn3 (YjeF N-terminal domain containing 3) - Rat Genome Database
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Gene: Yjefn3 (YjeF N-terminal domain containing 3) Mus musculus
Analyze
Symbol: Yjefn3
Name: YjeF N-terminal domain containing 3
RGD ID: 1621315
MGI Page MGI
Description: Predicted to have NADHX epimerase activity and NADPHX epimerase activity. Predicted to be involved in lipid transport. Predicted to localize to mitochondrion. Orthologous to human YJEFN3 (YjeF N-terminal domain containing 3); INTERACTS WITH benzo[a]pyrene; pirinixic acid; aflatoxin B1 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apoA-I-binding protein 2; Gm175; hYjeF_N3; yjeF N-terminal domain-containing protein 3; YjeF_N3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,340,438 - 70,346,633 (-)NCBIGRCm39mm39
GRCm38869,887,788 - 69,893,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,887,788 - 69,902,712 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,411,716 - 72,417,874 (-)NCBIGRCm37mm9NCBIm37
MGSCv36872,816,476 - 72,822,964 (-)NCBImm8
Celera872,446,530 - 72,452,678 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14610273   PMID:17533573   PMID:17967808   PMID:21267068   PMID:21873635   PMID:23375831   PMID:24154525  


Genomics

Comparative Map Data
Yjefn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,340,438 - 70,346,633 (-)NCBIGRCm39mm39
GRCm38869,887,788 - 69,893,983 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,887,788 - 69,902,712 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,411,716 - 72,417,874 (-)NCBIGRCm37mm9NCBIm37
MGSCv36872,816,476 - 72,822,964 (-)NCBImm8
Celera872,446,530 - 72,452,678 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
YJEFN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1919,528,861 - 19,537,581 (+)EnsemblGRCh38hg38GRCh38
GRCh381919,528,901 - 19,537,584 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371919,639,670 - 19,648,393 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,500,720 - 19,509,393 (+)NCBINCBI36hg18NCBI36
Celera1919,543,732 - 19,552,455 (+)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1919,201,895 - 19,210,613 (+)NCBIHuRef
CHM1_11919,640,582 - 19,649,297 (+)NCBICHM1_1
Yjefn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01621,282,355 - 21,288,656 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,282,467 - 21,288,406 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01621,198,438 - 21,204,519 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41620,011,423 - 20,024,519 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1619,722,785 - 19,729,087 (+)NCBICelera
Cytogenetic Map16p14NCBI
Yjefn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,421,350 - 2,426,509 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,421,350 - 2,426,509 (-)NCBIChiLan1.0ChiLan1.0
YJEFN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11919,964,456 - 19,973,200 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,964,456 - 19,973,200 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01918,966,788 - 18,976,052 (+)NCBIMhudiblu_PPA_v0panPan3
YJEFN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2043,703,274 - 43,722,505 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12043,713,245 - 43,721,494 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Yjefn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365961,937,234 - 1,945,742 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YJEFN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,392,513 - 58,402,023 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,392,515 - 58,401,408 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,296,551 - 58,305,491 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YJEFN3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,990,831 - 18,000,433 (+)NCBI
Yjefn3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249082,319,805 - 2,325,264 (+)NCBI

Position Markers
AI429575  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,894,363 - 69,894,571UniSTSGRCm38
MGSCv37872,418,262 - 72,418,470UniSTSGRCm37
Celera872,453,066 - 72,453,274UniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map8B3.3UniSTS
Whitehead/MRC_RH8738.71UniSTS
Whitehead/MRC_RH8741.75UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:764
Count of miRNA genes:255
Interacting mature miRNAs:280
Transcripts:ENSMUST00000152456, ENSMUST00000152938, ENSMUST00000180068
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000152456
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,887,790 - 69,888,185 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152938   ⟹   ENSMUSP00000118931
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,887,788 - 69,893,975 (-)Ensembl
RefSeq Acc Id: ENSMUST00000180068   ⟹   ENSMUSP00000136145
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl869,887,788 - 69,902,712 (-)Ensembl
RefSeq Acc Id: NM_001353930   ⟹   NP_001340859
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,340,438 - 70,346,633 (-)NCBI
GRCm38869,887,788 - 69,893,983 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001340859 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH28663 (Get FASTA)   NCBI Sequence Viewer  
  F6W8I0 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001340859   ⟸   NM_001353930
RefSeq Acc Id: ENSMUSP00000118931   ⟸   ENSMUST00000152938
RefSeq Acc Id: ENSMUSP00000136145   ⟸   ENSMUST00000180068
Protein Domains
YjeF N-terminal

Promoters
RGD ID:6843894
Promoter ID:MM_KWN:54647
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Lung
Transcripts:ENSMUST00000057831,   OTTMUST00000085596
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,411,206 - 72,413,017 (-)MPROMDB
RGD ID:6843924
Promoter ID:MM_KWN:54648
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney
Transcripts:LINCRNA_1011,   OTTMUST00000085595
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,414,786 - 72,415,437 (-)MPROMDB
RGD ID:6848897
Promoter ID:MM_TRO:9536
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   ES_Cell,   Kidney,   Liver
Transcripts:MTR065365.8.1158.0
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,417,831 - 72,418,362 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2681845 AgrOrtholog
Ensembl Genes ENSMUSG00000048967 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000118931 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000136145 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000152938 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000180068 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro YjeF_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  YjeF_N_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  YJEFN_prot_eukaryotes UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2681845 ENTREZGENE
NCBI Gene 234365 ENTREZGENE
PANTHER PTHR13232 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam YjeF_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Yjefn3 PhenoGen
PROSITE YJEF_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF64153 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs yjeF_nterm UniProtKB/Swiss-Prot
UniGene Mm.252521 ENTREZGENE
UniProt A0A0A0MQP0_MOUSE UniProtKB/TrEMBL
  F6W8I0 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary J3QM68 UniProtKB/Swiss-Prot
  Q8R2K0 UniProtKB/Swiss-Prot