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Gene: Setd2 (SET domain containing 2) Mus musculus
Symbol: Setd2
Name: SET domain containing 2
Description: ENCODES a protein that exhibits histone methyltransferase activity (H3-K36 specific); alpha-tubulin binding (ortholog); histone-lysine N-methyltransferase activity (ortholog); INVOLVED IN angiogenesis; cell migration involved in vasculogenesis; coronary vasculature morphogenesis; PARTICIPATES IN histone modification pathway; renal cell carcinoma pathway; lysine degradation pathway; ASSOCIATED WITH abnormal blood vessel morphology; abnormal head development; abnormal placenta labyrinth morphology; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); Breast Neoplasms (ortholog); FOUND IN chromosome; nucleus; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4921524K10Rik; BC031601; histone-lysine N-methyltransferase SETD2; KMT3A; lysine N-methyltransferase 3A; protein-lysine N-methyltransferase SETD2; SET domain-containing protein 2
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389110,532,500 - 110,618,633 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379110,435,101 - 110,521,137 (+)NCBIGRCm37mm9NCBIm37
MGSCv369110,393,444 - 110,463,449 (+)NCBImm8
Celera9110,275,024 - 110,348,565 (+)NCBICelera
Cytogenetic Map9 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Setd2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1621311
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.