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Gene: Setd2 (SET domain containing 2) Mus musculus
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Symbol: Setd2
Name: SET domain containing 2
Description: ENCODES a protein that exhibits histone methyltransferase activity (H3-K36 specific); alpha-tubulin binding (ortholog); histone-lysine N-methyltransferase activity (ortholog); INVOLVED IN angiogenesis; cell migration involved in vasculogenesis; coronary vasculature morphogenesis; PARTICIPATES IN histone modification pathway; renal cell carcinoma pathway; lysine degradation pathway; ASSOCIATED WITH abnormal blood vessel morphology; abnormal head development; abnormal placenta labyrinth morphology; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); Breast Neoplasms (ortholog); FOUND IN chromosome; nucleus; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4921524K10Rik; BC031601; histone-lysine N-methyltransferase SETD2; KMT3A; lysine N-methyltransferase 3A; protein-lysine N-methyltransferase SETD2; SET domain-containing protein 2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389110,532,500 - 110,618,633 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379110,435,101 - 110,521,137 (+)NCBIGRCm37mm9NCBIm37
MGSCv369110,393,444 - 110,463,449 (+)NCBImm8
Celera9110,275,024 - 110,348,565 (+)NCBICelera
Cytogenetic Map9 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Setd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1621311
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.