Olfm2 (olfactomedin 2) - Rat Genome Database

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Gene: Olfm2 (olfactomedin 2) Mus musculus
Analyze
Symbol: Olfm2
Name: olfactomedin 2
RGD ID: 1621285
MGI Page MGI
Description: Acts upstream of or within locomotory behavior and visual perception. Located in synaptic membrane. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Is extrinsic component of synaptic membrane. Is expressed in several structures, including central nervous system; eye; and orbito-sphenoid. Orthologous to human OLFM2 (olfactomedin 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A030009A06Rik; noelin-2; olfactomedin-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,578,986 - 20,657,660 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,578,986 - 20,657,645 (-)EnsemblGRCm39 Ensembl
GRCm38920,667,690 - 20,746,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,667,690 - 20,746,349 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,472,430 - 20,532,658 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,418,102 - 20,478,631 (-)NCBIMGSCv36mm8
Celera917,938,428 - 17,996,310 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21228389   PMID:21267068  
PMID:21873635   PMID:22632720   PMID:25218043   PMID:28062493   PMID:32325033   PMID:34321999   PMID:35026233   PMID:37591201  


Genomics

Comparative Map Data
Olfm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,578,986 - 20,657,660 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,578,986 - 20,657,645 (-)EnsemblGRCm39 Ensembl
GRCm38920,667,690 - 20,746,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,667,690 - 20,746,349 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,472,430 - 20,532,658 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,418,102 - 20,478,631 (-)NCBIMGSCv36mm8
Celera917,938,428 - 17,996,310 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.6NCBI
OLFM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,853,718 - 9,936,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl199,853,718 - 9,936,515 (-)EnsemblGRCh38hg38GRCh38
GRCh37199,964,394 - 10,047,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,825,394 - 9,908,070 (-)NCBINCBI36Build 36hg18NCBI36
Build 34199,825,394 - 9,908,070NCBI
Celera199,859,823 - 9,942,535 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,545,037 - 9,627,331 (-)NCBIHuRef
CHM1_1199,964,109 - 10,046,786 (-)NCBICHM1_1
T2T-CHM13v2.0199,979,884 - 10,062,687 (-)NCBIT2T-CHM13v2.0
Olfm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,480,703 - 27,558,416 (-)NCBIGRCr8
mRatBN7.2819,204,472 - 19,282,154 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,204,475 - 19,282,117 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,224,798 - 23,283,196 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,522,638 - 21,581,036 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,434,221 - 19,493,166 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,684,307 - 21,762,000 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,681,266 - 21,743,338 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0821,740,363 - 21,818,045 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,685,433 - 19,746,974 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1819,685,433 - 19,746,974 (-)NCBI
Celera820,599,780 - 20,658,825 (-)NCBICelera
Cytogenetic Map8q13NCBI
Olfm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,264,831 - 1,328,877 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,264,831 - 1,328,877 (-)NCBIChiLan1.0ChiLan1.0
OLFM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22014,772,348 - 14,855,375 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11913,774,905 - 13,855,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,408,161 - 9,488,855 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,071,375 - 10,151,178 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,071,375 - 10,151,183 (-)Ensemblpanpan1.1panPan2
OLFM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12051,148,013 - 51,153,303 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2051,148,157 - 51,153,314 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,955,590 - 51,016,889 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,613,108 - 51,674,476 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,612,962 - 51,674,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,820,875 - 50,882,225 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,245,805 - 51,307,078 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,486,759 - 51,548,349 (+)NCBIUU_Cfam_GSD_1.0
Olfm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,969,055 - 210,029,710 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659325,436 - 372,225 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936659324,996 - 385,646 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OLFM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl268,734,081 - 68,807,191 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1268,734,078 - 68,807,207 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,063,856 - 69,135,514 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OLFM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.168,939,966 - 8,947,913 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl68,939,603 - 8,947,678 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607411,068,366 - 11,161,713 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Olfm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,135,245 - 2,200,332 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,134,728 - 2,200,354 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Olfm2
2556 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:240
Count of miRNA genes:222
Interacting mature miRNAs:224
Transcripts:ENSMUST00000034692
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902913Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130341840Mouse
35673312Ari7_mantibody response to influenza 7, day 45, IgG3 (mouse)9780000122211296Mouse
1300849Sles4_msystemic lupus erythmatosus suppressor 4 (mouse)Not determined9910756237306370Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse

Markers in Region
Olfm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9A3UniSTS
cM Map97.6UniSTS
Olfm2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38920,672,276 - 20,672,714UniSTSGRCm38
Celera917,942,718 - 17,943,156UniSTS
Cytogenetic Map9A3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000034692   ⟹   ENSMUSP00000034692
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,578,986 - 20,639,525 (-)Ensembl
GRCm38.p6 Ensembl920,667,690 - 20,728,229 (-)Ensembl
RefSeq Acc Id: ENSMUST00000215039
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,583,628 - 20,584,427 (-)Ensembl
GRCm38.p6 Ensembl920,672,332 - 20,673,131 (-)Ensembl
RefSeq Acc Id: ENSMUST00000215999   ⟹   ENSMUSP00000149231
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,578,989 - 20,657,645 (-)Ensembl
GRCm38.p6 Ensembl920,667,693 - 20,746,349 (-)Ensembl
RefSeq Acc Id: ENSMUST00000217198   ⟹   ENSMUSP00000151018
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,578,992 - 20,638,233 (-)Ensembl
GRCm38.p6 Ensembl920,667,696 - 20,726,937 (-)Ensembl
RefSeq Acc Id: NM_001357635   ⟹   NP_001344564
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,578,986 - 20,638,299 (-)NCBI
GRCm38920,667,690 - 20,727,003 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001357639   ⟹   NP_001344568
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,578,986 - 20,657,592 (-)NCBI
GRCm38920,667,690 - 20,746,296 (-)NCBI
Sequence:
RefSeq Acc Id: NM_173777   ⟹   NP_776138
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,578,986 - 20,639,525 (-)NCBI
GRCm38920,667,690 - 20,728,229 (-)NCBI
MGSCv37920,472,430 - 20,532,658 (-)RGD
Celera917,938,428 - 17,996,310 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030244363   ⟹   XP_030100223
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,578,987 - 20,657,660 (-)NCBI
GRCm38920,667,691 - 20,746,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030244364   ⟹   XP_030100224
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,578,987 - 20,638,508 (-)NCBI
GRCm38920,667,691 - 20,726,756 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030244365   ⟹   XP_030100225
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,578,987 - 20,586,864 (-)NCBI
GRCm38920,667,691 - 20,673,128 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_776138   ⟸   NM_173777
- Peptide Label: isoform 3 precursor
- UniProtKB: Q0VFZ0 (UniProtKB/Swiss-Prot),   Q0VG58 (UniProtKB/Swiss-Prot),   Q8BM13 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001344568   ⟸   NM_001357639
- Peptide Label: isoform 2 precursor
- UniProtKB: A0A1L1SQX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001344564   ⟸   NM_001357635
- Peptide Label: isoform 1
- UniProtKB: A0A1L1SV46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030100223   ⟸   XM_030244363
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030100224   ⟸   XM_030244364
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030100225   ⟸   XM_030244365
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000151018   ⟸   ENSMUST00000217198
RefSeq Acc Id: ENSMUSP00000034692   ⟸   ENSMUST00000034692
RefSeq Acc Id: ENSMUSP00000149231   ⟸   ENSMUST00000215999
Protein Domains
Olfactomedin-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BM13-F1-model_v2 AlphaFold Q8BM13 1-448 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3045350 AgrOrtholog
Ensembl Genes ENSMUSG00000032172 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000034692 ENTREZGENE
  ENSMUST00000034692.9 UniProtKB/Swiss-Prot
  ENSMUST00000215999 ENTREZGENE
  ENSMUST00000215999.2 UniProtKB/TrEMBL
  ENSMUST00000217198 ENTREZGENE
  ENSMUST00000217198.2 UniProtKB/TrEMBL
InterPro Noelin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Olfac-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:244723 UniProtKB/Swiss-Prot
MGD MGI:3045350 ENTREZGENE
NCBI Gene 244723 ENTREZGENE
PANTHER OLFACTOMEDIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23192:SF27 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Noelin-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OLF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Olfm2 PhenoGen
PROSITE OLF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART OLF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SQX6 ENTREZGENE, UniProtKB/TrEMBL
  A0A1L1SV46 ENTREZGENE, UniProtKB/TrEMBL
  NOE2_MOUSE UniProtKB/Swiss-Prot
  Q0VFZ0 ENTREZGENE
  Q0VG58 ENTREZGENE
  Q8BM13 ENTREZGENE
UniProt Secondary Q0VFZ0 UniProtKB/Swiss-Prot
  Q0VG58 UniProtKB/Swiss-Prot