Crocc2 (ciliary rootlet coiled-coil, rootletin family member 2) - Rat Genome Database

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Gene: Crocc2 (ciliary rootlet coiled-coil, rootletin family member 2) Mus musculus
Analyze
Symbol: Crocc2
Name: ciliary rootlet coiled-coil, rootletin family member 2
RGD ID: 1621187
MGI Page MGI
Description: Predicted to be active in centriole and centrosome. Is expressed in central nervous system; dorsal root ganglion; embryo mesenchyme; and lung. Orthologous to human CROCC2 (ciliary rootlet coiled-coil, rootletin family member 2).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ciliary rootlet coiled-coil protein 2; E030010N08Rik; Gm976; putative ciliary rootlet coiled-coil protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,096,145 - 93,158,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,096,447 - 93,158,794 (+)EnsemblGRCm39 Ensembl
GRCm38193,168,423 - 93,231,067 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,168,725 - 93,231,072 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,065,302 - 95,127,649 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,999,131 - 95,061,480 (+)NCBIMGSCv36mm8
Celera196,113,378 - 96,175,767 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:27914912  


Genomics

Comparative Map Data
Crocc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,096,145 - 93,158,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,096,447 - 93,158,794 (+)EnsemblGRCm39 Ensembl
GRCm38193,168,423 - 93,231,067 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,168,725 - 93,231,072 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,065,302 - 95,127,649 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,999,131 - 95,061,480 (+)NCBIMGSCv36mm8
Celera196,113,378 - 96,175,767 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.17NCBI
CROCC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,906,336 - 240,993,311 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,906,330 - 240,993,311 (+)EnsemblGRCh38hg38GRCh38
GRCh372241,845,753 - 241,932,728 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,491,914 - 241,581,401 (+)NCBINCBI36Build 36hg18NCBI36
Celera2235,525,451 - 235,600,411 (+)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2233,630,832 - 233,647,812 (+)NCBIHuRef
CHM1_12241,878,338 - 241,911,575 (+)NCBICHM1_1
T2T-CHM13v2.02241,405,412 - 241,492,295 (+)NCBIT2T-CHM13v2.0
Crocc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,155,815 - 101,217,036 (+)NCBIGRCr8
mRatBN7.2993,708,786 - 93,769,617 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl993,708,684 - 93,769,402 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.09100,314,988 - 100,376,006 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0999,967,218 - 100,033,051 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4992,456,914 - 92,503,028 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera991,244,020 - 91,304,746 (+)NCBICelera
Cytogenetic Map9q36NCBI
Crocc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542646,143 - 694,682 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955542647,145 - 694,523 (-)NCBIChiLan1.0ChiLan1.0
CROCC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213143,594,943 - 143,678,874 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B143,609,908 - 143,693,824 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B128,164,643 - 128,248,255 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B246,967,325 - 247,048,780 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B246,967,325 - 247,050,201 (+)Ensemblpanpan1.1panPan2
CROCC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12550,994,194 - 51,046,435 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2551,004,465 - 51,038,700 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2551,216,846 - 51,266,381 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02551,198,427 - 51,248,148 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12551,030,968 - 51,095,863 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02550,786,031 - 50,835,491 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,062,010 - 51,111,670 (+)NCBIUU_Cfam_GSD_1.0
Crocc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,378,922 - 192,438,562 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936745782,495 - 840,280 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CROCC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15139,766,414 - 139,811,999 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115139,749,160 - 139,817,779 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215154,902,554 - 154,934,056 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CROCC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110126,983,470 - 127,052,328 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604072,333,885 - 72,413,862 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crocc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248475,095,451 - 5,142,313 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248475,095,183 - 5,145,196 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Crocc2
1995 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:673
Count of miRNA genes:429
Interacting mature miRNAs:484
Transcripts:ENSMUST00000138595
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162946755120529678Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167339159129727737Mouse
1302146Cocrb1_mcocaine related behavior 1 (mouse)Not determined170133533104139557Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173266214108838414Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73615692107615830Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173615692107615830Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)175976637128527737Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177123115110536075Mouse
14697706Stsl3a_mSalmonella typhimurium susceptibility locus 3a (mouse)17747663795827725Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179858683113858791Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179858683113858791Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180245593126386517Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182832635116832635Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182832635116832635Mouse
11667074Led2_mlate embryonic death 2 (mouse)185696027117195081Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186483929120483929Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89786512123786512Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189786512123786512Mouse
4141347Reb1_mrepetitive behavior 1 (mouse)Not determined91468266100413667Mouse
1357760Synch3_msynechia 3 (mouse)Not determined192901442126901550Mouse
4141627Bwq7_mbody weight, QTL 7 (mouse)Not determined192940909124497796Mouse

Markers in Region
G42365  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38728,587,179 - 28,587,270UniSTSGRCm38
GRCm38193,216,181 - 93,216,948UniSTSGRCm38
MGSCv37729,372,198 - 29,372,289UniSTSGRCm37
MGSCv37195,112,758 - 95,113,525UniSTSGRCm37
Celera723,152,294 - 23,152,385UniSTS
Celera196,160,835 - 96,161,604UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map1DUniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001310428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006529994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003956157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003956159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004942947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC103673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000138595   ⟹   ENSMUSP00000120588
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl193,096,447 - 93,158,794 (+)Ensembl
GRCm38.p6 Ensembl193,168,725 - 93,231,072 (+)Ensembl
RefSeq Acc Id: NM_001310428   ⟹   NP_001297357
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
GRCm38193,168,423 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529983   ⟹   XP_006530046
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
GRCm38193,168,423 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529984   ⟹   XP_006530047
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
GRCm38193,168,423 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529985   ⟹   XP_006530048
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,104,140 - 93,158,789 (+)NCBI
GRCm38193,176,418 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529986   ⟹   XP_006530049
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
GRCm38193,168,423 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529991   ⟹   XP_006530054
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,111,116 - 93,158,789 (+)NCBI
GRCm38193,184,487 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529992   ⟹   XP_006530055
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,116,025 - 93,158,789 (+)NCBI
GRCm38193,188,303 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006529994   ⟹   XP_006530057
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,151,374 (+)NCBI
GRCm38193,168,423 - 93,223,652 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255127   ⟹   XP_030110987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
GRCm38193,168,423 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036166086   ⟹   XP_036021979
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003956157
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
GRCm38193,168,423 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003956159
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
GRCm38193,168,423 - 93,231,067 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004942947
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39193,096,145 - 93,158,789 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_006530057   ⟸   XM_006529994
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_006530046   ⟸   XM_006529983
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006530049   ⟸   XM_006529986
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006530047   ⟸   XM_006529984
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006530048   ⟸   XM_006529985
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006530054   ⟸   XM_006529991
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006530055   ⟸   XM_006529992
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: NP_001297357   ⟸   NM_001310428
- UniProtKB: F6XLV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030110987   ⟸   XM_030255127
- Peptide Label: isoform X6
RefSeq Acc Id: ENSMUSP00000120588   ⟸   ENSMUST00000138595
RefSeq Acc Id: XP_036021979   ⟸   XM_036166086
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F6XLV1-F1-model_v2 AlphaFold F6XLV1 1-1638 view protein structure

Promoters
RGD ID:6874532
Promoter ID:EPDNEW_M717
Type:multiple initiation site
Name:Crocc2_1
Description:Mus musculus ciliary rootlet coiled-coil, rootletin family member2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38193,168,614 - 93,168,674EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3045962 AgrOrtholog
Ensembl Genes ENSMUSG00000084989 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000138595 ENTREZGENE
  ENSMUST00000138595.3 UniProtKB/Swiss-Prot
KEGG Report mmu:381284 UniProtKB/Swiss-Prot
MGD MGI:3045962 ENTREZGENE
NCBI Gene 381284 ENTREZGENE
PANTHER CENTROSOMAL PROTEIN 2 UniProtKB/Swiss-Prot
  CILIARY ROOTLET COILED-COIL PROTEIN 2 UniProtKB/Swiss-Prot
Pfam Rootletin UniProtKB/Swiss-Prot
PhenoGen Crocc2 PhenoGen
UniProt CRCC2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-26 Crocc2  ciliary rootlet coiled-coil, rootletin family member 2  E030010N08Rik  RIKEN cDNA E030010N08 gene  Symbol and/or name change 5135510 APPROVED