H2bc26 (H2B clustered histone 26) - Rat Genome Database

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Gene: H2bc26 (H2B clustered histone 26) Mus musculus
Analyze
Symbol: H2bc26 (Ensembl: H2bc26-ps)
Name: H2B clustered histone 26 (Ensembl:H2B clustered histone 26, pseudogene)
RGD ID: 1621184
MGI Page MGI
Description: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of nucleosome. Orthologous to human H2BC26 (H2B clustered histone 26).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4930534G10Rik; 4933432H21; B2Hist3h2bb; H2B-clustered histone 26; H2B.U histone 1, pseudogene; H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps; histone 3, H2bb; histone cluster 3, H2bb, pseudogene; histone H2B type 3-B; MGC130256; R75370
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,842,961 - 58,845,278 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,844,874 - 58,845,254 (-)EnsemblGRCm39 Ensembl
GRCm381158,954,048 - 58,954,512 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,954,048 - 58,954,512 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,767,550 - 58,768,014 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,770,243 - 58,770,707 (-)NCBIMGSCv36mm8
Celera1163,720,373 - 63,720,837 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (IEA)
cytosol  (ISO)
extracellular space  (ISO)
nucleoplasm  (ISO,TAS)
nucleosome  (IEA)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12408966   PMID:12466851   PMID:12477932   PMID:15197225   PMID:15489334   PMID:16039583   PMID:16916647   PMID:18311719  
PMID:20362542   PMID:21873635   PMID:23665500   PMID:27746211   PMID:30713523  


Genomics

Comparative Map Data
H2bc26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391158,842,961 - 58,845,278 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1158,844,874 - 58,845,254 (-)EnsemblGRCm39 Ensembl
GRCm381158,954,048 - 58,954,512 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,954,048 - 58,954,512 (-)EnsemblGRCm38mm10GRCm38
MGSCv371158,767,550 - 58,768,014 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361158,770,243 - 58,770,707 (-)NCBIMGSCv36mm8
Celera1163,720,373 - 63,720,837 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1136.38NCBI
H2BC26
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381228,458,103 - 228,458,558 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1228,458,103 - 228,463,104 (+)EnsemblGRCh38hg38GRCh38
GRCh371228,645,804 - 228,646,259 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,712,431 - 226,712,882 (+)NCBINCBI36Build 36hg18NCBI36
Build 341224,952,542 - 224,952,994NCBI
Celera1201,835,703 - 201,836,154 (+)NCBICelera
Cytogenetic Map1q42.13NCBI
HuRef1199,160,443 - 199,160,894 (+)NCBIHuRef
CHM1_11229,918,079 - 229,918,530 (+)NCBICHM1_1
T2T-CHM13v2.01227,646,615 - 227,647,070 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in H2bc26
187 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:138
Interacting mature miRNAs:145
Transcripts:ENSMUST00000117558
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115406567067078411Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115408094165103841Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5406567063319522Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
13513917Heal54_mwound healing/ regeneration 54 (mouse)115787291759879610Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse

Markers in Region
UniSTS:487841  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,954,048 - 58,954,512UniSTSGRCm38
MGSCv371158,767,550 - 58,768,014UniSTSGRCm37
Celera1163,720,373 - 63,720,837UniSTS
Cytogenetic Map11B2UniSTS
UniSTS:493024  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,954,048 - 58,954,512UniSTSGRCm38
MGSCv371158,767,550 - 58,768,014UniSTSGRCm37
Celera1163,720,373 - 63,720,837UniSTS
Cytogenetic Map11B2UniSTS
MDB0529  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,955,392 - 58,955,545UniSTSGRCm38
MGSCv371158,768,894 - 58,769,047UniSTSGRCm37
Celera1163,721,717 - 63,721,870UniSTS
Cytogenetic Map11B2UniSTS
Whitehead_YAC11 UniSTS
RH125217  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,955,381 - 58,955,532UniSTSGRCm38
MGSCv371158,768,883 - 58,769,034UniSTSGRCm37
Celera1163,721,706 - 63,721,857UniSTS
Cytogenetic Map11B2UniSTS
Hist1h2bc  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map3F1-F2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map13A3.1UniSTS
cM Map13 UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000117558
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1158,844,874 - 58,845,254 (-)Ensembl
GRCm38.p6 Ensembl1158,954,048 - 58,954,512 (-)Ensembl
RefSeq Acc Id: NM_001393523   ⟹   NP_001380452
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391158,842,961 - 58,845,278 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001380452 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI07302 (Get FASTA)   NCBI Sequence Viewer  
  AAI07303 (Get FASTA)   NCBI Sequence Viewer  
  AAO06253 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00001091675
  ENSMUSP00001091675.1
GenBank Protein Q8CGP0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001380452   ⟸   NM_001393523
- UniProtKB: Q8CGP0 (UniProtKB/Swiss-Prot),   Q3B7Z7 (UniProtKB/Swiss-Prot),   A0JLV3 (UniProtKB/TrEMBL)
Protein Domains
Histone H2A/H2B/H3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CGP0-F1-model_v2 AlphaFold Q8CGP0 1-126 view protein structure

Promoters
RGD ID:6821091
Promoter ID:MM_KWN:7608
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000047697,   NM_206882
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361158,767,959 - 58,768,459 (-)MPROMDB
RGD ID:8674778
Promoter ID:EPDNEW_M15419
Type:multiple initiation site
Name:Hist3h2bb-ps_1
Description:Mus musculus histone cluster 3, H2bb, pseudogene (Hist3h2bb-ps),non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381158,954,452 - 58,954,512EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922442 AgrOrtholog
Ensembl Genes ENSMUSG00000080712 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000117558 ENTREZGENE
  ENSMUST00000117558.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Histone-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A/H2B/H3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1922442 ENTREZGENE
NCBI Gene 382522 ENTREZGENE
PANTHER HISTONE H2B UniProtKB/TrEMBL
  HISTONE H2B TYPE 1-L UniProtKB/TrEMBL
  HISTONE H2B TYPE 3-B UniProtKB/Swiss-Prot
  PTHR23428 UniProtKB/Swiss-Prot
Pfam Histone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen H2bc26 PhenoGen
PRINTS HISTONEH2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HISTONE_H2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART H2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Histone-fold UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A0JLV3 ENTREZGENE, UniProtKB/TrEMBL
  H2B3B_MOUSE UniProtKB/Swiss-Prot
  Q3B7Z7 ENTREZGENE
  Q8CGP0 ENTREZGENE
UniProt Secondary Q3B7Z7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-31 H2bc26  H2B clustered histone 26  H2bc26-ps  H2B clustered histone 26, pseudogene  Symbol and/or name updated 27372883 PROVISIONAL
2022-06-27 H2bc26-ps  H2B clustered histone 26, pseudogene  H2bu1-ps  H2B.U histone 1, pseudogene  Symbol and/or name updated 27372883 PROVISIONAL
2019-08-13 H2bu1-ps  H2B.U histone 1, pseudogene  Hist3h2bb-ps  histone cluster 3, H2bb, pseudogene  Symbol and/or name change 5135510 APPROVED
2011-07-27 Hist3h2bb-ps  histone cluster 3, H2bb, pseudogene  Hist3h2bb  histone cluster 3, H2bb  Symbol and/or name change 5135510 APPROVED