Serpinb3d (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D) - Rat Genome Database
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Gene: Serpinb3d (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D) Mus musculus
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Symbol: Serpinb3d
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D
RGD ID: 1621173
MGI Page MGI
Description: Orthologous to human SERPINB3 (serpin family B member 3) and SERPINB4 (serpin family B member 4); PARTICIPATES IN Entamoebiasis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 17beta-estradiol (ortholog); 3-phenylprop-2-enal (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3D; serine proteinase inhibitor B3-like 1; serpin B3; Serpinb3l1
RGD Orthologs
Human
Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm8080   Gm8084  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391107,005,893 - 107,011,210 (-)NCBIGRCm39mm39
GRCm39 Ensembl1107,005,897 - 107,011,236 (-)Ensembl
GRCm381107,078,163 - 107,083,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1107,078,167 - 107,083,506 (-)EnsemblGRCm38mm10GRCm38
MGSCv371108,974,770 - 108,980,057 (-)NCBIGRCm37mm9NCBIm37
MGSCv361108,905,740 - 108,911,027 (-)NCBImm8
Celera1109,926,247 - 109,931,536 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:12477932   PMID:15060002   PMID:15203214   PMID:15203215   PMID:16602821   PMID:21403642   PMID:21677750   PMID:21873635   PMID:24172014  


Genomics

Comparative Map Data
Serpinb3d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391107,005,893 - 107,011,210 (-)NCBIGRCm39mm39
GRCm39 Ensembl1107,005,897 - 107,011,236 (-)Ensembl
GRCm381107,078,163 - 107,083,480 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1107,078,167 - 107,083,506 (-)EnsemblGRCm38mm10GRCm38
MGSCv371108,974,770 - 108,980,057 (-)NCBIGRCm37mm9NCBIm37
MGSCv361108,905,740 - 108,911,027 (-)NCBImm8
Celera1109,926,247 - 109,931,536 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
SERPINB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1863,655,197 - 63,661,893 (-)EnsemblGRCh38hg38GRCh38
GRCh381863,655,197 - 63,661,893 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371861,322,431 - 61,329,127 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,473,411 - 59,480,094 (-)NCBINCBI36hg18NCBI36
Build 341859,473,410 - 59,480,094NCBI
Celera1858,042,926 - 58,049,692 (-)NCBI
Cytogenetic Map18q21.33NCBI
HuRef1858,022,262 - 58,029,029 (-)NCBIHuRef
CHM1_11861,318,618 - 61,325,385 (-)NCBICHM1_1
Serpinb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21323,274,120 - 23,280,082 (-)NCBI
Rnor_6.0 Ensembl1327,187,130 - 27,192,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01327,186,701 - 27,193,211 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01332,336,215 - 32,341,680 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,339,447 - 13,344,912 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1323,119,963 - 23,125,428 (-)NCBICelera
Cytogenetic Map13p11NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139093727126517573Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
1301748Abbp1_mA/J and C57BL/6 blood pressure 1 (mouse)Not determined162907596120601949Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
27095918Ulnl1_mulna length 1, 5 week (mouse)167300000129800000Mouse
1300976Bmd19_mbone mineral density 19 (mouse)Not determined173227055108910684Mouse
4142394Mssq1_mmandible size and shape QTL 1 (mouse)Not determined73687970107688108Mouse
1301304Hrq3_mheart rate quantitative locus 3 (mouse)Not determined173687970107688108Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74477076148839837Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174952818133363199Mouse
27095931Pglq1_mpelvic girdle length QTL 1, 5 week (mouse)176000000128600000Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)176000000148900000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
1558928Mord2_mmodifier of retinal degeneration 2 (mouse)Not determined177146478110608345Mouse
4141725Wbcq4_mwhite blood cell quantitative locus 4 (mouse)Not determined179930958113931066Mouse
12050069Nabq1_mnasal bone morphology QTL 1 (mouse)179930958113931066Mouse
13452395Leusq2_mleucocytosis susceptibility QTL 2 (mouse)180267876126458780Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782314261147249632Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182665468135687641Mouse
10412238Alpq5_malcohol preference QTL 5 (mouse)Not determined182904910116904910Mouse
12791004Aath7_maortic arch atherosclerosis 7 (mouse)182904910116904910Mouse
11667074Led2_mlate embryonic death 2 (mouse)185768306117267351Mouse
12790991Aath1_maortic arch atherosclerosis 1 (mouse)186556204120556204Mouse
4141329Mleu1_mmyeloid leukemia survival 1 (mouse)Not determined89858782123858782Mouse
15039333Nmrs1_mNAFLD-associated magnetic resonance shift 1 (mouse)189858782123858782Mouse
1357760Synch3_msynechia 3 (mouse)Not determined192973712126973820Mouse
4141627Bwq7_mbody weight, QTL 7 (mouse)Not determined193013187124570059Mouse
12879491Hfnq1_mhair follicle number QTL 1 (mouse)193382588123709030Mouse
10045976Tir6_mtrypanosome infection response 6 (mouse)Not determined193609133120601949Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194200000148900000Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195600000162200000Mouse
1301123Cd8mts2_mCD8 memory T cell subset 2 (mouse)Not determined196690656130690827Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197126256131126460Mouse
13452398Leusq5_mleucocytosis susceptibility QTL 5 (mouse)198547060126458780Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199579930133580115Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1103040804137040937Mouse
12879492Ecgnq1_meccrine gland number QTL 1 (mouse)1103350337120607496Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:64
Interacting mature miRNAs:65
Transcripts:ENSMUST00000023861
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000023861   ⟹   ENSMUSP00000023861
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1107,078,167 - 107,083,506 (-)Ensembl
RefSeq Acc Id: NM_201376   ⟹   NP_958764
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391107,005,923 - 107,011,210 (-)NCBI
GRCm381107,078,193 - 107,083,480 (-)NCBI
MGSCv371108,974,770 - 108,980,057 (-)RGD
Celera1109,926,247 - 109,931,536 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017321541   ⟹   XP_017177030
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391107,005,893 - 107,011,210 (-)NCBI
GRCm381107,078,163 - 107,083,480 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017321551   ⟹   XP_017177040
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391107,005,893 - 107,011,210 (-)NCBI
GRCm381107,078,163 - 107,083,480 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_958764   ⟸   NM_201376
- UniProtKB: Q6UKZ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017177040   ⟸   XM_017321551
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017177030   ⟸   XM_017321541
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000023861   ⟸   ENSMUST00000023861
Protein Domains
SERPIN


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2683295 AgrOrtholog
Ensembl Genes ENSMUSG00000058017 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000023861 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023861 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
InterPro Protease_inhib_I4_serpin UniProtKB/TrEMBL
  Protease_inhib_I4_serpin_CS UniProtKB/TrEMBL
  Sepin_dom UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
KEGG Report mmu:394252 UniProtKB/TrEMBL
MGD MGI:2683295 ENTREZGENE
NCBI Gene 394252 ENTREZGENE
PANTHER Prot_inh_serpin UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PhenoGen Serpinb3d PhenoGen
PROSITE SERPIN UniProtKB/TrEMBL
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP Prot_inh_serpin UniProtKB/TrEMBL
UniProt Q6IE30_MOUSE UniProtKB/TrEMBL
  Q6UKZ0 ENTREZGENE, UniProtKB/TrEMBL