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Gene: Grb10 (growth factor receptor bound protein 10) Mus musculus
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Symbol: Grb10
Name: growth factor receptor bound protein 10
Description: Exhibits SH3/SH2 adaptor activity and insulin receptor binding activity. Involved in several processes, including ERK1 and ERK2 cascade; negative regulation of glucose import; and negative regulation of signal transduction. Predicted to localize to the protein-containing complex. Is expressed in several structures, including branchial arch; extraembryonic component; genitourinary system; sensory organ; and ventricular layer. Orthologous to human GRB10 (growth factor receptor bound protein 10); PARTICIPATES IN insulin signaling pathway; insulin-like growth factor signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730571D09Rik; AI325020; GRB10 adapter protein; growth factor receptor-bound protein 10; maternally expressed gene 1 protein; Meg1; mKIAA0207
Orthologs:
Homo sapiens (human) : GRB10 (growth factor receptor bound protein 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grb10 (growth factor receptor bound protein 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb10 (growth factor receptor bound protein 10)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB10 (growth factor receptor bound protein 10)
Canis lupus familiaris (dog) : GRB10 (growth factor receptor bound protein 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb10 (growth factor receptor bound protein 10)
Sus scrofa (pig) : GRB10 (growth factor receptor bound protein 10)
Chlorocebus sabaeus (African green monkey) : GRB10 (growth factor receptor bound protein 10)
Heterocephalus glaber (naked mole-rat) : Grb10 (growth factor receptor bound protein 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1111,930,508 - 12,038,683 (-)EnsemblGRCm38mm10GRCm38
GRCm381111,930,499 - 12,037,428 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371111,830,502 - 11,937,423 (-)NCBIGRCm37mm9NCBIm37
MGSCv361111,830,511 - 11,937,358 (-)NCBImm8
Celera1112,389,743 - 12,487,174 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Grb10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1620908
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.