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Gene: Grb10 (growth factor receptor bound protein 10) Mus musculus
Symbol: Grb10
Name: growth factor receptor bound protein 10
Description: Exhibits SH3/SH2 adaptor activity and insulin receptor binding activity. Involved in several processes, including ERK1 and ERK2 cascade; negative regulation of glucose import; and negative regulation of signal transduction. Predicted to localize to the protein-containing complex. Is expressed in several structures, including branchial arch; extraembryonic component; genitourinary system; sensory organ; and ventricular layer. Orthologous to human GRB10 (growth factor receptor bound protein 10); PARTICIPATES IN insulin signaling pathway; insulin-like growth factor signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730571D09Rik; AI325020; GRB10 adapter protein; growth factor receptor-bound protein 10; maternally expressed gene 1 protein; Meg1; mKIAA0207
Homo sapiens (human) : GRB10 (growth factor receptor bound protein 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grb10 (growth factor receptor bound protein 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb10 (growth factor receptor bound protein 10)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB10 (growth factor receptor bound protein 10)
Canis lupus familiaris (dog) : GRB10 (growth factor receptor bound protein 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb10 (growth factor receptor bound protein 10)
Sus scrofa (pig) : GRB10 (growth factor receptor bound protein 10)
Chlorocebus sabaeus (African green monkey) : GRB10 (growth factor receptor bound protein 10)
Heterocephalus glaber (naked mole-rat) : Grb10 (growth factor receptor bound protein 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1111,930,508 - 12,038,683 (-)EnsemblGRCm38mm10GRCm38
GRCm381111,930,499 - 12,037,428 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371111,830,502 - 11,937,423 (-)NCBIGRCm37mm9NCBIm37
MGSCv361111,830,511 - 11,937,358 (-)NCBImm8
Celera1112,389,743 - 12,487,174 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Grb10
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1620908
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.