Mocs3 (molybdenum cofactor synthesis 3)

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Gene: Mocs3 (molybdenum cofactor synthesis 3) Mus musculus

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Symbol:

Mocs3

Name:

molybdenum cofactor synthesis 3

RGD ID:

1620801

MGI Page

MGI

Description:

Predicted to enable URM1 activating enzyme activity; nucleotidyltransferase activity; and sulfurtransferase activity. Predicted to be involved in Mo-molybdopterin cofactor biosynthetic process; protein urmylation; and tRNA wobble position uridine thiolation. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in central nervous system; retina inner nuclear layer; retina layer; and retina outer nuclear layer. Orthologous to human MOCS3 (molybdenum cofactor synthesis 3).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

1700020H17Rik; adenylyltransferase and sulfurtransferase MOCS3; molybdenum cofactor synthesis protein 3; molybdopterin synthase sulfurylase; MPT synthase sulfurylase; Uba; Uba4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MOCS3 (molybdenum cofactor synthesis 3)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Mocs3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mocs3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MOCS3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MOCS3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mocs3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MOCS3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MOCS3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mocs3 (molybdenum cofactor synthesis 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Mocs3 (molybdenum cofactor synthesis 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MOCS3 (molybdenum cofactor synthesis 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mocs3 (molybdenum cofactor synthesis 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	moc-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UBA4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Uba4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mocs3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	168,072,542 - 168,074,223 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	168,072,542 - 168,074,514 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	168,230,622 - 168,232,303 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	168,230,622 - 168,232,594 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	168,056,122 - 168,057,803 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	167,921,827 - 167,923,801 (+)	NCBI		MGSCv36	mm8
Celera	2	174,174,727 - 174,176,408 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	88.5	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation Ie (ISO)

Hydrops Fetalis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

1,2-dimethylhydrazine (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

cadmium dichloride (ISO)

chlorpyrifos (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

Dibutyl phosphate (ISO)

fenthion (EXP)

folic acid (EXP)

gentamycin (ISO)

iron dichloride (ISO)

methidathion (EXP)

paracetamol (EXP)

perfluorohexanesulfonic acid (EXP)

rac-lactic acid (ISO)

sevoflurane (EXP)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (ISO)

thiram (ISO)

titanium dioxide (EXP)

urethane (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Mo-molybdopterin cofactor biosynthetic process (ISO,ISS)

molybdopterin cofactor biosynthetic process (ISO)

molybdopterin cofactor metabolic process (ISO)

protein urmylation (IBA)

tRNA thio-modification (ISO,ISS)

tRNA wobble position uridine thiolation (IBA,IEA)

tRNA wobble uridine modification (ISO,ISS)

Cellular Component

cytoplasm (IBA,ISO)

cytosol (ISO,ISS)

Molecular Function

ATP binding (IEA)

metal ion binding (IEA)

molybdopterin-synthase adenylyltransferase activity (IEA)

molybdopterin-synthase sulfurtransferase activity (ISO,ISS)

nucleotidyltransferase activity (IBA,ISO,ISS)

protein binding (ISO)

sulfurtransferase activity (ISO,ISS)

thiosulfate sulfurtransferase activity (IBA)

URM1 activating enzyme activity (IBA,ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

molybdenum cofactor biosynthetic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Cell biology of molybdenum.	Mendel RR and Bittner F, Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:15226823	PMID:16141072	PMID:16141073	PMID:16602821
PMID:21873635	PMID:23593335

Genomics

Comparative Map Data

Mocs3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	168,072,542 - 168,074,223 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	168,072,542 - 168,074,514 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	168,230,622 - 168,232,303 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	168,230,622 - 168,232,594 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	168,056,122 - 168,057,803 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	167,921,827 - 167,923,801 (+)	NCBI		MGSCv36	mm8
Celera	2	174,174,727 - 174,176,408 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	88.5	NCBI

MOCS3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	50,958,818 - 50,963,929 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	50,958,818 - 50,963,929 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	49,575,355 - 49,580,466 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	49,008,770 - 49,011,227 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	49,008,769 - 49,011,227	NCBI
Celera	20	46,279,623 - 46,282,080 (+)	NCBI		Celera
Cytogenetic Map	20	q13.13	NCBI
HuRef	20	46,323,922 - 46,326,971 (+)	NCBI		HuRef
CHM1_1	20	49,480,642 - 49,483,691 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	52,729,421 - 52,734,532 (+)	NCBI		T2T-CHM13v2.0

Mocs3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	177,358,639 - 177,360,599 (+)	NCBI		GRCr8
mRatBN7.2	3	156,939,763 - 156,941,723 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	156,939,809 - 156,941,890 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	160,734,559 - 160,736,519 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	169,233,657 - 169,235,617 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	166,975,357 - 166,977,317 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	164,986,421 - 164,988,381 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	164,986,421 - 164,988,369 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	171,125,683 - 171,127,643 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	159,393,645 - 159,395,605 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	159,299,677 - 159,301,073 (+)	NCBI
Celera	3	155,513,119 - 155,515,079 (+)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

Mocs3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	7,470,888 - 7,472,267 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955445	7,470,030 - 7,472,323 (-)	NCBI	ChiLan1.0	ChiLan1.0

MOCS3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	56,710,029 - 56,712,278 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	56,703,146 - 56,705,872 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	47,305,561 - 47,310,809 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	48,432,496 - 48,435,534 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	48,432,519 - 48,433,901 (+)	Ensembl	panpan1.1		panPan2

MOCS3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	37,268,781 - 37,271,581 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	37,268,808 - 37,270,304 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	36,510,770 - 36,513,446 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	37,978,399 - 37,981,075 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	37,978,427 - 37,979,923 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	37,213,898 - 37,216,575 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	37,347,791 - 37,350,464 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	37,892,834 - 37,895,510 (+)	NCBI		UU_Cfam_GSD_1.0

Mocs3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	188,376,546 - 188,378,551 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	3,830,627 - 3,832,009 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	3,830,189 - 3,832,194 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MOCS3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	52,377,348 - 52,380,260 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	52,377,343 - 52,379,711 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	58,817,392 - 58,819,760 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MOCS3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	13,011,922 - 13,014,409 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	13,012,821 - 13,014,203 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	61,442,062 - 61,447,320 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mocs3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624790	4,796,765 - 4,798,153 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624790	4,793,371 - 4,798,156 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	102
Count of miRNA genes:	99
Interacting mature miRNAs:	101
Transcripts:	ENSMUST00000099071
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1301907	Rends_m	renal disease susceptibility (mouse)			Not determined		2	135699221	169699361	Mouse
1300688	Nidd2k_m	Nidd2 on KK-A (mouse)			Not determined		2	158078337	178442452	Mouse
1558867	Gnf3_m	growth and fatness 3 (mouse)			Not determined		2	152699221	169117924	Mouse
1301783	Bhr1_m	bronchial hyperresponsiveness 1 (mouse)			Not determined		2	142593476	178442452	Mouse
12790983	Bwq12_m	body weight QTL 12 (mouse)					2	148238204	181755017	Mouse
11038701	Ltpr2e_m	Leishmania tropica response 2e (mouse)					2	150212221	181755017	Mouse
1301019	Bmd6_m	bone mineral density 6 (mouse)			Not determined		2	151778297	181755017	Mouse
1558939	Gnf1_m	growth and fatness 1 (mouse)			Not determined		2	143773445	169117924	Mouse
4142450	Lmr16_m	leishmaniasis resistance 16 (mouse)			Not determined		2	150212221	181755017	Mouse
1301085	Lrnx10_m	learning-contextual 10 (mouse)			Not determined		2	150212221	181755017	Mouse
11353826	Bdln10_m	body length 10 (mouse)					2	140441482	174441482	Mouse
1300867	Lore2_m	loss of righting induced by ethanol 2 (mouse)			Not determined		2	144515861	180896594	Mouse
1301378	Hpdty_m	hindlimb polydactyly (mouse)			Not determined		2	165664893	168623678	Mouse
1558917	Gct8_m	granulosa cell tumorigenesis 8 (mouse)			Not determined		2	149236907	181755017	Mouse
1300806	Aod4_m	autoimmune ovarian dysgenesis 4 (mouse)			Not determined		2	145228719	179228841	Mouse
12910800	Pwgrq3_m	pre-weaning growth rate QTL 3 (mouse)					2	160611165	169794802	Mouse
1300676	Prdt2_m	prion disease incubation time 2 (mouse)			Not determined		2	164515154	181755017	Mouse
1558991	Tailq4_m	tail length QTL 4 (mouse)			Not determined		2	162736926	178442452	Mouse
14747002	Mancz3_m	mandible centroid size 3 (mouse)					2	152329820	181755017	Mouse
1300751	Bdt1_m	bone density traits 1 (mouse)			Not determined		2	149988902	181755017	Mouse
1300622	Cfld1_m	cystic fibrosis lung disease 1 (mouse)			Not determined		2	155823920	181755017	Mouse
12910810	Pwbwq2_m	pre-weaning body weight QTL 2 (mouse)					2	160611165	169794802	Mouse
1302003	Sluc17_m	susceptibility to lung cancer 17 (mouse)			Not determined		2	162433493	181755017	Mouse
1301618	Bglu1_m	blood glucose level 1 (mouse)			Not determined		2	117942930	174324863	Mouse
27226749	Femd10_m	femur midshaft diameter 10, 16 week (mouse)					2	124441920	168241920	Mouse
10054066	Bwq9_m	body weight QTL 9 (mouse)			Not determined		2	135699221	169699361	Mouse
12738409	Lfibq1_m	liver fibrosis QTL 1 (mouse)					2	167716420	179207088	Mouse
10043956	Gnf5_m	growth and fatness 5 (mouse)			Not determined		2	135699221	169699361	Mouse
1302013	Tbbmd3_m	total body bone mineral density 3 (mouse)			Not determined		2	145196949	179197085	Mouse
1357435	Epfq2_m	epididymal fat pad weight QTL 2 (mouse)			Not determined		2	162736926	178442452	Mouse
5491196	Mobq6_m	multigenic obesity QTL 6 (mouse)			Not determined		2	85724269	180896594	Mouse
12801456	Intmrm1_m	intima/media ratio modifier 1 (mouse)					2	142428347	176428450	Mouse
1357537	Lith12_m	lithogenic gene 12 (mouse)			Not determined		2	156196464	181755017	Mouse
12801461	Intim1_m	intima modifier 1 (mouse)					2	142428347	176428450	Mouse
1301348	Alcp5_m	alcohol preference locus 5 (mouse)			Not determined		2	163486407	181755017	Mouse
4141703	Chlq13_m	circulating hormone level QTL 13 (mouse)			Not determined		2	135699221	169699361	Mouse
11341717	Rvfs1_m	Rift Valley fever susceptibility 1 (mouse)					2	135432544	173449616	Mouse
1301865	Hdlq19_m	HDL QTL 19 (mouse)			Not determined		2	145518775	179518926	Mouse
4142211	Nilac3_m	nicotine induced locomotor activity 3 (mouse)			Not determined		2	148664893	181755017	Mouse
12910520	Scgq3_m	spontaneous crescentic glomerulonephritis QTL 3 (mouse)					2	151709273	174389124	Mouse
1300846	Pbwg11_m	postnatal body weight growth 11 (mouse)			Not determined		2	138966600	172966729	Mouse
1301677	Alcp6_m	alcohol preference locus 6 (mouse)			Not determined		2	163486407	181755017	Mouse

Markers in Region

UniSTS:234612

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	2	168,231,758 - 168,231,971	UniSTS	GRCm38
MGSCv37	2	168,057,258 - 168,057,471	UniSTS	GRCm37
Celera	2	174,175,863 - 174,176,076	UniSTS
Cytogenetic Map	2	H3	UniSTS

UniSTS:493293

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	2	168,230,423 - 168,232,113	UniSTS	GRCm38
MGSCv37	2	168,055,923 - 168,057,613	UniSTS	GRCm37
Celera	2	174,174,528 - 174,176,218	UniSTS
Cytogenetic Map	2	H3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001160330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AK006163	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC115985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE133066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE333092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BG083535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX005039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BY727851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000099071 ⟹ ENSMUSP00000096670

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	168,072,542 - 168,074,514 (+)	Ensembl
GRCm38.p6 Ensembl	2	168,230,622 - 168,232,594 (+)	Ensembl

RefSeq Acc Id:

NM_001160330 ⟹ NP_001153802

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	168,072,542 - 168,074,223 (+)	NCBI
GRCm38	2	168,230,622 - 168,232,303 (+)	ENTREZGENE
MGSCv37	2	168,056,122 - 168,057,803 (+)	RGD
Celera	2	174,174,727 - 174,176,408 (+)	RGD
cM Map	2		ENTREZGENE

Sequence:

show sequence

GGAAGAGGCTGTCATGGCTGCCCCGGAGGACGTAGCTGCCTTACAGGCTGAAATCACCCGGCGG
GAGGAAGAGCTAGCTTCGCTCAAGCGGAGGCTGGCCGCGGCCCTGACAGCCGAGCCGGAGCCCG
AGCGTCCGCTCCGGGTCCCGCCGCCGCCGCTGGCGCCCCGGGCCGCGCTGTCGCGGGACGAGAT
CCTCCGCTACAGCCGCCAGCTACTGCTGCCGGAGCTGGGCGTGCGCGGGCAGCTGCGCCTGGCG
GCGGCGGCGGTGCTCGTGGTGGGCTGCGGCGGGCTGGGCTGCCCGCTGGCGCAGTACCTGGCGG
CGGCCGGCGTAGGCAGGCTGGGGCTGGTGGACCACGACGTGGTGGAGACGAGCAACCTGGCCCG
CCAGGTCCTGCACGGGGAGGCGCAGGCCGGCGAGAGCAAGGCTCGCTCGGCGGCCGCGGCGCTG
CGCCGTCTCAACTCGGCGGTGGAGTGCGTGGCGTACCCGCGCGCGCTCGCCGAGGACTGGGCGC
TCGACCTGGTCCGCGGCTACGACGTGGTGGCAGACTGCTGCGACAACGTGCCCACGCGCTACCT
GGTGAACGACGCGTGCGTGCTGGCCGGCCGGCCGCTAGTGTCGGCCAGCGCGCTGCGCTTCGAG
GGCCAGATGACCGTCTACCACCACGACGGCGGGCCGTGCTACCGCTGCGTGTTCCCGCGGCCGC
CCCCGCCGGAGACAGTGACCAACTGTGCAGACGGCGGCGTGCTCGGAGCGGTGCCCGGCGTGCT
AGGCTGCGCGCAGGCCCTCGAGGTGCTCAAGATCGCCGCCGGCCTCGGCTCCTCCTACAGCGGC
AGCATGCTGCTCTTCGACGGCCTCGGGGGCCACTTCCGCCGGATCCGGCTGCGGCGCCGCCGGC
CTGACTGCGTCGTGTGCGGGCAGCAGCCCACCGTGACCCGCCTGCAGGACTACGAGGCCTTCTG
CGGCTCCTCGGCCACCGACAAGTGCCGCGCCCTGAAGCTGCTGTGCCCCGAGGAGCGGATTTCT
GTGACCGACTACAAGCGGCTTCTGGATTCCGGGGCGCCCCATGTGTTGCTGGACGTCCGGCCTC
AAGTAGAGGTGGACATCTGTCGCCTGCCGCACTCTCTCCACATCCCTTTGAGTCAGTTGGAACG
CAGGGATGCGGACAGCCTGAAACTCTTAGGGGCTGCCCTCCGGAAAGGGAAGCAGGAGTCGCAG
GAAGGGGTTGCTCTCCCGGTGTATGTGATTTGCAAACTGGGAAACGACTCCCAGAAAGCTGTGA
AGGTCCTGCAGTCCTTAACGGCAGTGCCGGAGTTAGACTCTTTAACTGTTCAGGACATCGTGGG
GGGACTCATGGCCTGGGCCGCCAAAATTGATGGGACATTTCCACAGTACTGAGAGGACAGCATG
TGATTCGTGTGGATGACGGTTGTGATACCTGAAGAATCTATTCGAGCTTTACAAAATAATGTAG
GGAAGAGCCTGGATTCACGGTCTCCGAATAAATAAACGGAGACCTCCCCCCCCCCCCCCCCCAA
GGAGCTTTTTGAGAAAAGAGGATAGCATTGCCTCTGAGAGCTACTTTTGGGCACTTGTGCAGCA
CCTTCAACATGTGACTTGGTACGACAGGATTTTTTGTTTCCCACCCGGTCAGATTAAACTGAGA
TTAAACAGTTAAGATGCAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001153802	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A2BDX3	(Get FASTA)	NCBI Sequence Viewer
	AAI15986	(Get FASTA)	NCBI Sequence Viewer
	EDL06550	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000096670
	ENSMUSP00000096670.4

RefSeq Acc Id:

NP_001153802 ⟸ NM_001160330

- UniProtKB:

A2BDX3 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAAPEDVAALQAEITRREEELASLKRRLAAALTAEPEPERPLRVPPPPLAPRAALSRDEILRYS
RQLLLPELGVRGQLRLAAAAVLVVGCGGLGCPLAQYLAAAGVGRLGLVDHDVVETSNLARQVLH
GEAQAGESKARSAAAALRRLNSAVECVAYPRALAEDWALDLVRGYDVVADCCDNVPTRYLVNDA
CVLAGRPLVSASALRFEGQMTVYHHDGGPCYRCVFPRPPPPETVTNCADGGVLGAVPGVLGCAQ
ALEVLKIAAGLGSSYSGSMLLFDGLGGHFRRIRLRRRRPDCVVCGQQPTVTRLQDYEAFCGSSA
TDKCRALKLLCPEERISVTDYKRLLDSGAPHVLLDVRPQVEVDICRLPHSLHIPLSQLERRDAD
SLKLLGAALRKGKQESQEGVALPVYVICKLGNDSQKAVKVLQSLTAVPELDSLTVQDIVGGLMA
WAAKIDGTFPQY

hide sequence

Ensembl Acc Id:

ENSMUSP00000096670 ⟸ ENSMUST00000099071

Protein Domains

Rhodanese

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A2BDX3-F1-model_v2	AlphaFold	A2BDX3	1-460	view protein structure

Promoters

RGD ID:

6831212

Promoter ID:

MM_KWN:33144

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000109193, NM_001160330, NM_010072, OTTMUST00000038292, OTTMUST00000038293, OTTMUST00000038295, OTTMUST00000082923, UC008OAR.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	2	168,055,781 - 168,056,762 (-)	MPROMDB

RGD ID:

6879838

Promoter ID:

EPDNEW_M3370

Type:

multiple initiation site

Name:

Mocs3_1

Description:

Mus musculus molybdenum cofactor synthesis 3 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	2	168,230,622 - 168,230,682	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1916622	AgrOrtholog
Ensembl Genes	ENSMUSG00000074576	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000099071	ENTREZGENE
	ENSMUST00000099071.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.250.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NAD(P)-binding Rossmann-like Domain	UniProtKB/Swiss-Prot
InterPro	MOCS3/Uba4	UniProtKB/Swiss-Prot
	Rhodanese-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Rhodanese-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ThiF/MoeB/HesA	UniProtKB/Swiss-Prot
	ThiF_NAD_FAD-bd	UniProtKB/Swiss-Prot
	Ubiquitin-activating_enz	UniProtKB/Swiss-Prot
KEGG Report	mmu:69372	UniProtKB/Swiss-Prot
MGD	MGI:1916622	ENTREZGENE
NCBI Gene	69372	ENTREZGENE
PANTHER	ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3	UniProtKB/Swiss-Prot
	PTHR10953	UniProtKB/Swiss-Prot
Pfam	Rhodanese	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ThiF	UniProtKB/Swiss-Prot
PhenoGen	Mocs3	PhenoGen
PROSITE	RHODANESE_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	RHOD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Rhodanese-like	UniProtKB/TrEMBL
	SSF69572	UniProtKB/Swiss-Prot
UniProt	A2BDX3	ENTREZGENE, UniProtKB/Swiss-Prot
	Q14BE0_MOUSE	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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