Prr23a3 (proline rich 23A, member 3) - Rat Genome Database
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Gene: Prr23a3 (proline rich 23A, member 3) Mus musculus
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Symbol: Prr23a3
Name: proline rich 23A, member 3
RGD ID: 1620766
MGI Page MGI
Description: Is expressed in face. Orthologous to several human genes including PRR23B (proline rich 23B); INTERACTS WITH 1,2-dichloroethane; benzo[a]pyrene (ortholog); sodium arsenite (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410012M07Rik; MGC157616; proline-rich protein 23; proline-rich protein 23A3
RGD Orthologs
Human
Rat
Bonobo
Dog
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,746,820 - 98,748,633 (+)NCBIGRCm39mm39
GRCm38998,864,767 - 98,866,580 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,864,767 - 98,866,583 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,765,186 - 98,766,999 (+)NCBIGRCm37mm9NCBIm37
MGSCv36998,674,119 - 98,675,932 (+)NCBImm8
Celera998,397,329 - 98,399,141 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:24565867  


Genomics

Comparative Map Data
Prr23a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,746,820 - 98,748,633 (+)NCBIGRCm39mm39
GRCm38998,864,767 - 98,866,580 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,864,767 - 98,866,583 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,765,186 - 98,766,999 (+)NCBIGRCm37mm9NCBIm37
MGSCv36998,674,119 - 98,675,932 (+)NCBImm8
Celera998,397,329 - 98,399,141 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
PRR23A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3139,003,962 - 139,006,268 (-)EnsemblGRCh38hg38GRCh38
GRCh383139,003,962 - 139,006,268 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373138,722,804 - 138,725,110 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,207,000 - 140,207,800 (-)NCBINCBI36hg18NCBI36
Celera3137,149,254 - 137,151,560 (-)NCBI
Cytogenetic Map3q23NCBI
HuRef3136,098,241 - 136,100,547 (-)NCBIHuRef
CHM1_13138,686,760 - 138,689,066 (-)NCBICHM1_1
LOC684395
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08107,128,836 - 107,129,990 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08106,553,741 - 106,554,925 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera898,852,027 - 98,852,989 (+)NCBICelera
Cytogenetic Map8q31NCBI
PRR23A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13143,636,929 - 143,639,233 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v03136,036,884 - 136,039,488 (-)NCBIMhudiblu_PPA_v0panPan3
LOC611145
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12335,247,239 - 35,249,236 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1

Position Markers
UniSTS:492195  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38998,864,901 - 98,866,344UniSTSGRCm38
MGSCv37998,765,320 - 98,766,763UniSTSGRCm37
Celera998,397,463 - 98,398,905UniSTS
Cytogenetic Map9E3.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49541121101528921Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95212317899910428Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966207024100207122Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967124167101124167Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968897510102897652Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968897510102897652Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969239845103239920Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969546513103546645Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972977005106977152Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972977005106977152Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976117105101528921Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:217
Count of miRNA genes:176
Interacting mature miRNAs:189
Transcripts:ENSMUST00000167951
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000167951   ⟹   ENSMUSP00000130716
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl998,864,767 - 98,866,583 (+)Ensembl
RefSeq Acc Id: NM_028033   ⟹   NP_082309
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,746,820 - 98,748,633 (+)NCBI
GRCm38998,864,767 - 98,866,580 (+)ENTREZGENE
MGSCv37998,765,186 - 98,766,999 (+)RGD
Celera998,397,329 - 98,399,141 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_082309 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI28018 (Get FASTA)   NCBI Sequence Viewer  
  BAB26969 (Get FASTA)   NCBI Sequence Viewer  
  EDL20992 (Get FASTA)   NCBI Sequence Viewer  
  Q9CWP9 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_082309   ⟸   NM_028033
- UniProtKB: Q9CWP9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000130716   ⟸   ENSMUST00000167951

Promoters
RGD ID:6843950
Promoter ID:MM_KWN:58472
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:NM_028033
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36998,764,986 - 98,765,486 (+)MPROMDB
RGD ID:8670540
Promoter ID:EPDNEW_M13301
Type:initiation region
Name:Prr23a3_1
Description:Mus musculus proline rich 23A, member 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38998,864,792 - 98,864,852EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1919229 AgrOrtholog
Ensembl Genes ENSMUSG00000090470 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000130716 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000167951 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro PRR23 UniProtKB/Swiss-Prot
KEGG Report mmu:71979 UniProtKB/Swiss-Prot
MGD MGI:1919229 ENTREZGENE
NCBI Gene 71979 ENTREZGENE
Pfam DUF2476 UniProtKB/Swiss-Prot
PhenoGen Prr23a3 PhenoGen
UniGene Mm.140843 ENTREZGENE
UniProt P23A3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-23 Prr23a3  proline rich 23A, member 3  2410012M07Rik  RIKEN cDNA 2410012M07 gene  Symbol and/or name change 5135510 APPROVED