Hormad2 (HORMA domain containing 2) - Rat Genome Database

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Gene: Hormad2 (HORMA domain containing 2) Mus musculus
Analyze
Symbol: Hormad2
Name: HORMA domain containing 2
RGD ID: 1620730
MGI Page MGI
Description: Involved in meiotic sister chromatid cohesion. Acts upstream of or within meiotic cell cycle. Located in synaptonemal complex. Is expressed in ovary; spermatocyte; and testis. Orthologous to human HORMAD2 (HORMA domain containing 2); INTERACTS WITH genistein; acetamide (ortholog); atrazine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4930529M09Rik; HORMA domain-containing protein 2; RP23-329P17.4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,295,801 - 4,391,198 (-)NCBIGRCm39mm39
GRCm39 Ensembl114,295,814 - 4,391,105 (-)Ensembl
GRCm38114,345,801 - 4,441,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,345,814 - 4,441,105 (-)EnsemblGRCm38mm10GRCm38
MGSCv37114,246,386 - 4,341,085 (-)NCBIGRCm37mm9NCBIm37
MGSCv36114,246,565 - 4,327,807 (-)NCBImm8
Celera114,845,466 - 4,940,597 (-)NCBICelera
Cytogenetic Map11A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
acetamide  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
Cuprizon  (ISO)
genistein  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693   PMID:19851446  
PMID:21079677   PMID:21267068   PMID:21677750   PMID:22346761   PMID:22549958   PMID:22854038   PMID:23039116   PMID:27072294   PMID:27739607   PMID:28844861   PMID:30393076   PMID:32232159  


Genomics

Comparative Map Data
Hormad2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,295,801 - 4,391,198 (-)NCBIGRCm39mm39
GRCm39 Ensembl114,295,814 - 4,391,105 (-)Ensembl
GRCm38114,345,801 - 4,441,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,345,814 - 4,441,105 (-)EnsemblGRCm38mm10GRCm38
MGSCv37114,246,386 - 4,341,085 (-)NCBIGRCm37mm9NCBIm37
MGSCv36114,246,565 - 4,327,807 (-)NCBImm8
Celera114,845,466 - 4,940,597 (-)NCBICelera
Cytogenetic Map11A1NCBI
HORMAD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2230,080,464 - 30,177,075 (+)EnsemblGRCh38hg38GRCh38
GRCh382230,080,069 - 30,207,425 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372230,476,453 - 30,573,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362228,806,453 - 28,903,062 (+)NCBINCBI36hg18NCBI36
Build 342228,801,006 - 28,897,614NCBI
Celera2214,276,181 - 14,372,762 (+)NCBI
Cytogenetic Map22q12.2NCBI
HuRef2213,438,500 - 13,534,890 (+)NCBIHuRef
CHM1_12230,435,626 - 30,532,240 (+)NCBICHM1_1
Hormad2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21479,215,013 - 79,300,447 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1479,214,998 - 79,299,910 (-)Ensembl
Rnor_6.01484,576,856 - 84,662,237 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1484,576,825 - 84,662,222 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01485,258,458 - 85,343,171 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,971,123 - 85,056,271 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1478,124,840 - 78,209,277 (-)NCBICelera
Cytogenetic Map14q21NCBI
Hormad2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554554,317,319 - 4,424,645 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554554,309,397 - 4,462,932 (+)NCBIChiLan1.0ChiLan1.0
HORMAD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12228,919,699 - 29,015,951 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2228,920,640 - 29,015,949 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02211,113,654 - 11,213,291 (+)NCBIMhudiblu_PPA_v0panPan3
HORMAD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12623,254,313 - 23,342,644 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2623,254,415 - 23,339,947 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,125,597 - 23,213,985 (+)NCBI
ROS_Cfam_1.02623,629,535 - 23,724,667 (+)NCBI
UMICH_Zoey_3.12623,339,572 - 23,428,354 (+)NCBI
UNSW_CanFamBas_1.02623,602,484 - 23,691,252 (+)NCBI
UU_Cfam_GSD_1.02623,661,114 - 23,749,671 (+)NCBI
Hormad2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118116,187,617 - 116,257,617 (+)NCBI
SpeTri2.0NW_004936904477,398 - 546,574 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HORMAD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11912,965,088 - 13,057,576 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1912,977,944 - 13,007,296 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045113,089,685 - 113,180,451 (-)NCBIVero_WHO_p1.0
Hormad2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247476,388,679 - 6,493,583 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Hormad2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS
cM Map112.94UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123930487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11126026374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11126026374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11126026374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1127705234277232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11272035536721472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11330000018200000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11330000018500000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11330000019800000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11330000034600000Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11330000044200000Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1067
Count of miRNA genes:501
Interacting mature miRNAs:599
Transcripts:ENSMUST00000020689, ENSMUST00000109948, ENSMUST00000109949, ENSMUST00000124249, ENSMUST00000130174, ENSMUST00000149443
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000020689   ⟹   ENSMUSP00000020689
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl114,295,814 - 4,391,103 (-)Ensembl
GRCm38.p6 Ensembl114,345,814 - 4,441,103 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109948   ⟹   ENSMUSP00000105574
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl114,295,814 - 4,390,745 (-)Ensembl
GRCm38.p6 Ensembl114,345,814 - 4,440,745 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109949   ⟹   ENSMUSP00000105575
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl114,296,383 - 4,391,082 (-)Ensembl
GRCm38.p6 Ensembl114,346,383 - 4,441,082 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124249
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl114,377,314 - 4,385,754 (-)Ensembl
GRCm38.p6 Ensembl114,427,314 - 4,435,754 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130174   ⟹   ENSMUSP00000121715
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl114,374,248 - 4,391,105 (-)Ensembl
GRCm38.p6 Ensembl114,424,248 - 4,441,105 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149443
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl114,374,068 - 4,377,262 (-)Ensembl
GRCm38.p6 Ensembl114,424,068 - 4,427,262 (-)Ensembl
RefSeq Acc Id: NM_029458   ⟹   NP_083734
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,296,383 - 4,391,082 (-)NCBI
GRCm38114,346,383 - 4,441,082 (-)NCBI
MGSCv37114,246,386 - 4,341,085 (-)RGD
Celera114,845,466 - 4,940,597 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011243777   ⟹   XP_011242079
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,295,801 - 4,391,198 (-)NCBI
GRCm38114,345,801 - 4,441,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243779   ⟹   XP_011242081
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,295,801 - 4,391,198 (-)NCBI
GRCm38114,345,801 - 4,441,085 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243780   ⟹   XP_011242082
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,295,801 - 4,391,198 (-)NCBI
GRCm38114,345,801 - 4,441,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011243781   ⟹   XP_011242083
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,295,801 - 4,390,876 (-)NCBI
GRCm38114,345,801 - 4,440,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017314817   ⟹   XP_017170306
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,351,450 - 4,391,198 (-)NCBI
GRCm38114,401,450 - 4,441,198 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017314818   ⟹   XP_017170307
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39114,295,801 - 4,362,835 (-)NCBI
GRCm38114,345,801 - 4,412,835 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_083734   ⟸   NM_029458
- UniProtKB: Q5SQP1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242082   ⟸   XM_011243780
- Peptide Label: isoform X1
- UniProtKB: Q5SQP1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242079   ⟸   XM_011243777
- Peptide Label: isoform X1
- UniProtKB: Q5SQP1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242081   ⟸   XM_011243779
- Peptide Label: isoform X1
- UniProtKB: Q5SQP1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242083   ⟸   XM_011243781
- Peptide Label: isoform X1
- UniProtKB: Q5SQP1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017170307   ⟸   XM_017314818
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017170306   ⟸   XM_017314817
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000121715   ⟸   ENSMUST00000130174
RefSeq Acc Id: ENSMUSP00000020689   ⟸   ENSMUST00000020689
RefSeq Acc Id: ENSMUSP00000105574   ⟸   ENSMUST00000109948
RefSeq Acc Id: ENSMUSP00000105575   ⟸   ENSMUST00000109949
Protein Domains
HORMA

Promoters
RGD ID:6821073
Promoter ID:MM_KWN:6234
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:ENSMUST00000020689,   ENSMUST00000109948,   NM_029458,   OTTMUST00000011283
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36114,340,891 - 4,341,391 (-)MPROMDB
RGD ID:8673794
Promoter ID:EPDNEW_M14928
Type:initiation region
Name:Hormad2_1
Description:Mus musculus HORMA domain containing 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38114,441,052 - 4,441,112EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1923078 AgrOrtholog
Ensembl Genes ENSMUSG00000020419 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000020689 UniProtKB/TrEMBL
  ENSMUSP00000105574 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000105575 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000121715 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020689 UniProtKB/TrEMBL
  ENSMUST00000109948 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000109949 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000130174 UniProtKB/TrEMBL
Gene3D-CATH 3.30.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro HORMA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HORMA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75828 UniProtKB/Swiss-Prot
MGD MGI:1923078 ENTREZGENE
NCBI Gene 75828 ENTREZGENE
Pfam HORMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hormad2 PhenoGen
PROSITE HORMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56019 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1ATD3_MOUSE UniProtKB/TrEMBL
  H7BWX7_MOUSE UniProtKB/TrEMBL
  HORM2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B7ZMW2 UniProtKB/Swiss-Prot
  Q9D507 UniProtKB/Swiss-Prot