Plscr1l1 (phospholipid scramblase 1 like 1) - Rat Genome Database

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Gene: Plscr1l1 (phospholipid scramblase 1 like 1) Mus musculus
Analyze
No known orthologs.
Symbol: Plscr1l1 (Ensembl: 1700057G04Rik)
Name: phospholipid scramblase 1 like 1 (Ensembl:RIKEN cDNA 1700057G04 gene)
RGD ID: 1620713
MGI Page MGI
Description: Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: 1700057G04Rik; hypothetical protein LOC78459; novel Plsrc protein; RP23-21J17.1; uncharacterized protein LOC78459
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39992,191,379 - 92,239,929 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl992,191,430 - 92,239,929 (+)EnsemblGRCm39 Ensembl
GRCm38992,309,326 - 92,357,876 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl992,309,377 - 92,357,876 (+)EnsemblGRCm38mm10GRCm38
MGSCv37992,204,215 - 92,252,714 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36992,113,148 - 92,161,647 (+)NCBIMGSCv36mm8
Celera991,897,265 - 91,952,913 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map948.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21873635   PMID:34290169  


Genomics

Variants

.
Variants in Plscr1l1
2038 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:326
Count of miRNA genes:286
Interacting mature miRNAs:299
Transcripts:ENSMUST00000098477, ENSMUST00000126606, ENSMUST00000134712, ENSMUST00000135182, ENSMUST00000150594
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969121898103121973Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976024387101406120Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966089077100089175Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968779563102779705Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969428566103428698Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968779563102779705Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95936994693370128Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96214976796149881Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96926774798701707Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
11081165Psl6_mpromotion susceptibility QTL 6 (mouse)96504119195522808Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95902438793024534Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95902438793024534Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95936994693370128Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95936994693370128Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967006220101006220Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000098477   ⟹   ENSMUSP00000096077
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl992,191,430 - 92,239,929 (+)Ensembl
GRCm38.p6 Ensembl992,309,377 - 92,357,876 (+)Ensembl
RefSeq Acc Id: ENSMUST00000126606
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl992,191,430 - 92,209,167 (+)Ensembl
GRCm38.p6 Ensembl992,309,377 - 92,327,114 (+)Ensembl
RefSeq Acc Id: ENSMUST00000134712
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl992,191,461 - 92,233,124 (+)Ensembl
GRCm38.p6 Ensembl992,309,408 - 92,351,071 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135182   ⟹   ENSMUSP00000140686
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl992,233,138 - 92,239,929 (+)Ensembl
GRCm38.p6 Ensembl992,351,085 - 92,357,876 (+)Ensembl
RefSeq Acc Id: ENSMUST00000150594   ⟹   ENSMUSP00000117673
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl992,191,430 - 92,225,736 (+)Ensembl
GRCm38.p6 Ensembl992,309,377 - 92,343,683 (+)Ensembl
RefSeq Acc Id: ENSMUST00000185580   ⟹   ENSMUSP00000139734
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl992,225,558 - 92,239,872 (+)Ensembl
GRCm38.p6 Ensembl992,343,505 - 92,357,819 (+)Ensembl
RefSeq Acc Id: NM_001033184   ⟹   NP_001028356
RefSeq Status: PREDICTED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39992,191,430 - 92,239,929 (+)NCBI
GRCm38992,309,377 - 92,357,876 (+)NCBI
MGSCv37992,204,215 - 92,252,714 (+)RGD
Celera991,897,265 - 91,952,913 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011242837   ⟹   XP_011241139
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39992,191,381 - 92,239,926 (+)NCBI
GRCm38992,309,328 - 92,357,873 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011242838   ⟹   XP_011241140
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39992,191,379 - 92,239,926 (+)NCBI
GRCm38992,309,326 - 92,357,873 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011242839   ⟹   XP_011241141
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39992,225,672 - 92,239,926 (+)NCBI
GRCm38992,343,619 - 92,357,873 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001779073
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39992,191,385 - 92,239,926 (+)NCBI
GRCm38992,309,332 - 92,357,873 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001028356   ⟸   NM_001033184
- UniProtKB: Q3V0U0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241140   ⟸   XM_011242838
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011241139   ⟸   XM_011242837
- Peptide Label: isoform X1
- UniProtKB: Q3V0U0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241141   ⟸   XM_011242839
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000117673   ⟸   ENSMUST00000150594
RefSeq Acc Id: ENSMUSP00000139734   ⟸   ENSMUST00000185580
RefSeq Acc Id: ENSMUSP00000140686   ⟸   ENSMUST00000135182
RefSeq Acc Id: ENSMUSP00000096077   ⟸   ENSMUST00000098477

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3V0U0-F1-model_v2 AlphaFold Q3V0U0 1-232 view protein structure

Promoters
RGD ID:8670444
Promoter ID:EPDNEW_M13253
Type:initiation region
Name:1700057G04Rik_1
Description:Mus musculus RIKEN cDNA 1700057G04 gene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38992,309,377 - 92,309,437EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1925709 AgrOrtholog
Ensembl Genes ENSMUSG00000074139 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098477 ENTREZGENE
  ENSMUST00000098477.8 UniProtKB/TrEMBL
  ENSMUST00000135182.3 UniProtKB/TrEMBL
  ENSMUST00000150594.8 UniProtKB/TrEMBL
  ENSMUST00000185580.7 UniProtKB/TrEMBL
InterPro Scramblase UniProtKB/TrEMBL
  Tubby_C-like UniProtKB/TrEMBL
KEGG Report mmu:78459 UniProtKB/TrEMBL
MGD MGI:1925709 ENTREZGENE
NCBI Gene 78459 ENTREZGENE
PANTHER PHOSPHOLIPID SCRAMBLASE UniProtKB/TrEMBL
  PTHR23248 UniProtKB/TrEMBL
Pfam Scramblase UniProtKB/TrEMBL
PhenoGen Plscr1l1 PhenoGen
Superfamily-SCOP SSF54518 UniProtKB/TrEMBL
UniProt A0A087WPD9_MOUSE UniProtKB/TrEMBL
  A0A087WRL7_MOUSE UniProtKB/TrEMBL
  B1B193_MOUSE UniProtKB/TrEMBL
  Q3V0U0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-14 Plscr1l1  phospholipid scramblase 1 like 1  1700057G04Rik  RIKEN cDNA 1700057G04 gene  Symbol and/or name updated 27372883 PROVISIONAL