Tmsb15a (thymosin beta 15a) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Tmsb15a (thymosin beta 15a) Mus musculus
Analyze
Symbol: Tmsb15a
Name: thymosin beta 15a
RGD ID: 1620708
MGI Page MGI
Description: Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration and sequestering of actin monomers. Predicted to be active in cytoplasm. Is expressed in several structures, including heart; liver; lung; metanephros; and spleen. Orthologous to human TMSB15A (thymosin beta 15A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700129I15Rik; RP23-250F8.6; Tb15; Tb15a; thymosin beta-15A; thymosin beta-like protein 1; thymosin-like 8; Tms; Tmsbl1; Tmsl8
RGD Orthologs
Human
Chinchilla
Bonobo
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X134,619,416 - 134,626,010 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX134,619,416 - 134,626,010 (-)EnsemblGRCm39 Ensembl
GRCm38X135,718,667 - 135,725,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX135,718,667 - 135,725,261 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X132,253,206 - 132,255,212 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X131,065,031 - 131,067,039 (-)NCBIMGSCv36mm8
CeleraX119,035,807 - 119,037,839 (-)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX57.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14610273   PMID:16141072   PMID:16141073   PMID:19233202   PMID:21677750   PMID:21873635   PMID:23677977  
PMID:26341476  


Genomics

Comparative Map Data
Tmsb15a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X134,619,416 - 134,626,010 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX134,619,416 - 134,626,010 (-)EnsemblGRCm39 Ensembl
GRCm38X135,718,667 - 135,725,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX135,718,667 - 135,725,261 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X132,253,206 - 132,255,212 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X131,065,031 - 131,067,039 (-)NCBIMGSCv36mm8
CeleraX119,035,807 - 119,037,839 (-)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX57.26NCBI
TMSB15A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X102,513,682 - 102,516,739 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX102,513,682 - 102,516,739 (-)EnsemblGRCh38hg38GRCh38
GRCh37X101,768,610 - 101,771,667 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X101,655,266 - 101,658,355 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX102,207,240 - 102,210,329 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX91,433,976 - 91,437,049 (-)NCBIHuRef
CHM1_1X101,661,281 - 101,664,370 (-)NCBICHM1_1
T2T-CHM13v2.0X100,958,170 - 100,961,227 (-)NCBIT2T-CHM13v2.0
Tmsb15a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495554884,399 - 86,594 (-)NCBIChiLan1.0ChiLan1.0
TMSB15A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X102,124,449 - 102,127,539 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X102,128,054 - 102,131,144 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X91,742,014 - 91,745,110 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X102,122,672 - 102,125,764 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX102,122,671 - 102,125,780 (-)Ensemblpanpan1.1panPan2
TMSB15A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X83,744,536 - 83,747,599 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X97,684,765 - 97,687,815 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMSB15A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X90,497,649 - 90,500,805 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX90,498,057 - 90,499,132 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606515,327,664 - 15,330,777 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Tmsb15a
151 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:96
Count of miRNA genes:48
Interacting mature miRNAs:48
Transcripts:ENSMUST00000073674, ENSMUST00000113154
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412164Cmv2_mcytomegalovirus resistance 2 (mouse)Not determinedX125685149159685269Mouse
1558900Bw3_mbody weight QTL 3 (mouse)Not determinedX133540040165298595Mouse
1301209Cia19_mcollagen induced arthritis 19 (mouse)Not determinedX120993165160213038Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
13824981Svwq2_mseminal vesicle weight QTL 2 (mouse)X128900749153782996Mouse
25314309Syncl5_msynaptonemal complex length 5 (mouse)X121909697152582996Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse

Markers in Region
Tmsb15a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXF1UniSTS
cM MapX UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000073674   ⟹   ENSMUSP00000073355
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX134,619,416 - 134,621,422 (-)Ensembl
GRCm38.p6 EnsemblX135,718,667 - 135,720,673 (-)Ensembl
RefSeq Acc Id: ENSMUST00000113154   ⟹   ENSMUSP00000108779
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX134,619,416 - 134,626,010 (-)Ensembl
GRCm38.p6 EnsemblX135,718,667 - 135,725,261 (-)Ensembl
RefSeq Acc Id: NM_030106   ⟹   NP_084382
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X134,619,423 - 134,621,385 (-)NCBI
GRCm38X135,718,667 - 135,720,673 (-)NCBI
MGSCv37X132,253,206 - 132,255,212 (-)RGD
CeleraX119,035,807 - 119,037,839 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006528628   ⟹   XP_006528691
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X134,619,416 - 134,626,010 (-)NCBI
GRCm38X135,718,667 - 135,725,261 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006528629   ⟹   XP_006528692
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X134,619,423 - 134,621,430 (-)NCBI
GRCm38X135,718,674 - 135,720,681 (-)NCBI
Sequence:
RefSeq Acc Id: NP_084382   ⟸   NM_030106
- UniProtKB: Q9D2R9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006528691   ⟸   XM_006528628
- Peptide Label: isoform X1
- UniProtKB: A2AEH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006528692   ⟸   XM_006528629
- Peptide Label: isoform X2
- UniProtKB: Q9D2R9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000108779   ⟸   ENSMUST00000113154
RefSeq Acc Id: ENSMUSP00000073355   ⟸   ENSMUST00000073674

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2AEH9-F1-model_v2 AlphaFold A2AEH9 1-79 view protein structure

Promoters
RGD ID:13681394
Promoter ID:EPDNEW_M24846
Type:multiple initiation site
Name:Tmsb15a_1
Description:Mus musculus thymosin beta 15a , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X135,720,633 - 135,720,693EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1925728 AgrOrtholog
Ensembl Genes ENSMUSG00000060726 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000073674 ENTREZGENE
  ENSMUST00000073674.3 UniProtKB/TrEMBL
  ENSMUST00000113154 ENTREZGENE
  ENSMUST00000113154.8 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.520 UniProtKB/TrEMBL
InterPro Beta-thymosin_sf UniProtKB/TrEMBL
  Thymosin_b4 UniProtKB/TrEMBL
KEGG Report mmu:78478 UniProtKB/TrEMBL
MGD MGI:1925728 ENTREZGENE
NCBI Gene 78478 ENTREZGENE
PANTHER PTHR12021 UniProtKB/TrEMBL
  THYMOSIN BETA 15A UniProtKB/TrEMBL
Pfam Thymosin UniProtKB/TrEMBL
PhenoGen Tmsb15a PhenoGen
PIRSF Thymosin_beta UniProtKB/TrEMBL
SMART THY UniProtKB/TrEMBL
UniProt A2AEH9 ENTREZGENE, UniProtKB/TrEMBL
  Q9D2R9 ENTREZGENE, UniProtKB/TrEMBL