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Gene: Rdh9 (retinol dehydrogenase 9) Mus musculus
Analyze
Symbol:
Rdh9
Name:
retinol dehydrogenase 9
RGD ID:
1620679
MGI Page
MGI
Description:
Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within 9-cis-retinoic acid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in midbrain. Orthologous to human RDH16 (retinol dehydrogenase 16).
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
AI121090; cis-retinol/androgen dehydrogenase type 3; Cra; Crad3
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Rattus norvegicus (Norway rat):
Rdh9 (retinol dehydrogenase 9) RGD
RGD
Other homologs 2
Homo sapiens (human):
RDH16 (retinol dehydrogenase 16) HGNC
Ensembl, HGNC, HomoloGene, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Homo sapiens (human):
HSD17B6 (hydroxysteroid 17-beta dehydrogenase 6) HGNC
OrthoDB
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Rdh16 (retinol dehydrogenase 16)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
RDH16 (retinol dehydrogenase 16)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
AYR1
Alliance
DIOPT (Hieranoid|InParanoid)
Drosophila melanogaster (fruit fly):
CG8888
Alliance
DIOPT (Hieranoid|InParanoid|OrthoInspector|PANTHER|SonicParanoid)
Caenorhabditis elegans (roundworm):
dhs-20
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
rdh7.2
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
rdh7
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
rdh16
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
hsd17b6
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
mgc89248
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 10 127,612,274 - 127,628,566 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 10 127,612,255 - 127,628,566 (+) Ensembl GRCm39 Ensembl GRCm38 10 127,776,405 - 127,792,697 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 10 127,776,386 - 127,792,697 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 10 127,213,461 - 127,229,753 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 10 127,179,354 - 127,195,646 (+) NCBI MGSCv36 mm8 Celera 10 130,171,009 - 130,187,306 (+) NCBI Celera Cytogenetic Map 10 D3 NCBI cM Map 10 75.21 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Rdh9 Mouse (1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RDH9 mRNA CTD PMID:36331819 Rdh9 Mouse 17beta-hydroxy-5alpha-androstan-3-one increases chemical synthesis EXP 6480464 RDH9 protein results in increased chemical synthesis of Dihydrotestosterone CTD PMID:17270348 Rdh9 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of RDH9 mRNA more ... CTD PMID:16214954 more ... Rdh9 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of RDH9 mRNA CTD PMID:19465110 more ... Rdh9 Mouse 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression EXP 6480464 2 more ... CTD PMID:38648751 Rdh9 Mouse 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:19467301 Rdh9 Mouse 4,4'-sulfonyldiphenol decreases methylation EXP 6480464 bisphenol S results in decreased methylation of RDH9 promoter CTD PMID:33297965 Rdh9 Mouse 9-cis-retinal increases chemical synthesis EXP 6480464 RDH9 protein results in increased chemical synthesis of 9-cis-retinal CTD PMID:17270348 Rdh9 Mouse aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of RDH9 mRNA CTD PMID:19770486 Rdh9 Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of RDH9 mRNA CTD PMID:19770486 Rdh9 Mouse benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of RDH9 mRNA CTD PMID:26377693 Rdh9 Mouse beta-hexachlorocyclohexane decreases expression EXP 6480464 beta-hexachlorocyclohexane results in decreased expression of RDH9 mRNA CTD PMID:25270620 Rdh9 Mouse bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of RDH9 mRNA CTD PMID:19850644 Rdh9 Mouse bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of RDH9 mRNA] CTD PMID:19850644 Rdh9 Mouse bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of RDH9 promoter CTD PMID:27312807 Rdh9 Mouse bisphenol A decreases expression ISO Rdh9 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of RDH9 mRNA CTD PMID:25181051 Rdh9 Mouse cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of RDH9 mRNA CTD PMID:24067728 Rdh9 Mouse carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon analog results in increased expression of RDH9 mRNA CTD PMID:25620056 Rdh9 Mouse carnosic acid decreases expression EXP 6480464 salvin results in decreased expression of RDH9 protein CTD PMID:35926579 Rdh9 Mouse chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of RDH9 mRNA CTD PMID:28472532 Rdh9 Mouse doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of RDH9 mRNA CTD PMID:19277126 Rdh9 Mouse lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of RDH9 mRNA CTD PMID:21829687 Rdh9 Mouse leflunomide increases expression EXP 6480464 leflunomide results in increased expression of RDH9 mRNA CTD PMID:19751817 Rdh9 Mouse monosodium L-glutamate increases expression EXP 6480464 Sodium Glutamate results in increased expression of RDH9 mRNA CTD PMID:20111022 Rdh9 Mouse N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of RDH9 mRNA CTD PMID:24535843 Rdh9 Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of RDH9 mRNA CTD PMID:17562736 Rdh9 Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RDH9 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of RDH9 mRNA CTD PMID:36331819 Rdh9 Mouse phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of RDH9 mRNA CTD PMID:24535843 Rdh9 Mouse phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of RDH9 mRNA CTD PMID:23091169 Rdh9 Mouse pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of RDH9 mRNA CTD PMID:25270620 Rdh9 Mouse pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of RDH9 mRNA CTD PMID:28903501 Rdh9 Mouse propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of RDH9 mRNA CTD PMID:21278054 Rdh9 Mouse tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of RDH9 mRNA CTD PMID:31919559
(1->4)-beta-D-glucan (EXP) 17beta-hydroxy-5alpha-androstan-3-one (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP) 3,3',4,4'-tetrachlorobiphenyl (EXP) 4,4'-sulfonyldiphenol (EXP) 9-cis-retinal (EXP) aflatoxin B1 (EXP) benzo[a]pyrene (EXP) benzo[b]fluoranthene (EXP)
References
Additional References at PubMed
Genomics
Comparative Map Data
Rdh9 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 10 127,612,274 - 127,628,566 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 10 127,612,255 - 127,628,566 (+) Ensembl GRCm39 Ensembl GRCm38 10 127,776,405 - 127,792,697 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 10 127,776,386 - 127,792,697 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 10 127,213,461 - 127,229,753 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 10 127,179,354 - 127,195,646 (+) NCBI MGSCv36 mm8 Celera 10 130,171,009 - 130,187,306 (+) NCBI Celera Cytogenetic Map 10 D3 NCBI cM Map 10 75.21 NCBI
Rdh9 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 7 65,527,552 - 65,530,396 (-) NCBI GRCr8 mRatBN7.2 7 63,642,305 - 63,645,149 (-) NCBI mRatBN7.2 mRatBN7.2 Rnor_6.0 7 71,087,763 - 71,092,922 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_5.0 7 71,259,735 - 71,265,263 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 7 67,784,665 - 67,787,509 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 Celera 7 60,775,631 - 60,781,684 (-) NCBI Celera Cytogenetic Map 7 q22 NCBI
QTLs in Region (GRCm39)
4142461 Bmd25_m bone mineral density 25 (mouse) Not determined 10 97217101 130530862 Mouse 1301968 Estq4_m estradiol regulated response QTL 4 (mouse) Not determined 10 100986516 130530862 Mouse 12904001 Opfaq10_m open field activity QTL 10 (mouse) 10 125633671 129466375 Mouse 12879490 Frct3_m fear conditioning traits 3 (mouse) 10 122785970 129466996 Mouse 11049570 Lmr25b_m leishmaniasis resistance 25b (mouse) 10 108575094 130530862 Mouse 27226772 Tibl13_m tibia length 13, 10 week (mouse) 10 18875748 129635869 Mouse 4141361 Cfmq3_m cystic fibrosis modifier QTL 3 (mouse) Not determined 10 101497164 130530862 Mouse 11533921 Mvb2_m modifier of vibrator 2 (mouse) 10 97217101 130530862 Mouse 4141487 Tgq21_m triglyceride QTL 21 (mouse) Not determined 104110021 130530862 Mouse 27226764 Tibl19_m tibia length 19, 16 week (mouse) 10 39175996 129635869 Mouse 1301895 Exq1_m exploratory and excitability QTL 1 (mouse) Not determined 10 102847852 130530862 Mouse 1300679 Nociq2_m nociceptive sensitivity inflammatory QTL 2 (mouse) Not determined 10 105041304 130530862 Mouse 1300678 Leg2_m longevity extending gene 2 (mouse) Not determined 10 102506908 130530862 Mouse 14746996 Manh69_m mandible shape 69 (mouse) 10 104763638 130530862 Mouse 12880413 V125Dq9_m vitamin D active form serum level QTL 9 (mouse) 10 97535905 130530862 Mouse 1301901 Im5_m immunoregulatory 5 (mouse) Not determined 10 101497164 130530862 Mouse 4141153 Ltgq2_m liver triglyceride QTL 2 (mouse) Not determined 108515907 130530862 Mouse 11039496 Ltpr5b_m Leishmania tropica response 5b (mouse) 10 108575094 130530862 Mouse 1357744 Cfbw4_m cystic fibrosis body weight 4 (mouse) Not determined 10 100986516 130530862 Mouse 4141402 T2dm1sa_m type 2 diabetes mellitus 1 in SMXA RI mice (mouse) Not determined 97758644 130530862 Mouse 11041664 Lmr25_m leishmaniasis resistance 25 (mouse) 10 108575094 130530862 Mouse 1302200 Sle12_m systematic lupus erythematosus susceptibility 12 (mouse) Not determined 10 105041304 130530862 Mouse 26884405 Huml2_m humerus length 2, 5 week (mouse) 10 69735830 130430862 Mouse 4141007 Obrq10_m obesity resistance QTL 10 (mouse) Not determined 103243727 130530862 Mouse 11533919 Mvb4_m modifier of vibrator 4 (mouse) 3 97217101 130530862 Mouse 12911220 Frct3c_m fear conditioning traits 3c (mouse) 10 122785970 129466996 Mouse 11049563 Lmr25a_m leishmaniasis resistance 25a (mouse) 10 108575094 130530862 Mouse 4142089 Obrq9_m obesity resistance QTL 9 (mouse) Not determined 108515907 130530862 Mouse 12911218 Frct3a_m fear conditioning traits 3a (mouse) 10 122785970 129466996 Mouse 14696727 Kidrq2_m kidney weight, right QTL 2 (mouse) 10 102902508 130530862 Mouse 11040593 Lmr5e_m leishmaniasis resistance 5e (mouse) 10 99220635 130530862 Mouse 27095911 Pglq15_m pelvic girdle length QTL 15, 16 week (mouse) 10 39175996 129635869 Mouse 11040594 Lmr5f_m leishmaniasis resistance 5f (mouse) 10 105179713 130530862 Mouse 11040595 Lmr5c_m leishmaniasis resistance 5c (mouse) 10 99220635 130530862 Mouse 1357544 Vtbt10_m vertebral trabecular bone trait 10 (mouse) Not determined 10 97217101 130530862 Mouse 11040596 Lmr5d_m leishmaniasis resistance 5d (mouse) 10 105179713 130530862 Mouse 11040597 Lmr5a_m leishmaniasis resistance 5a (mouse) 10 99220635 130530862 Mouse 1357482 Nhdlq4_m non-HDL QTL 4 (mouse) Not determined 10 105041304 130530862 Mouse 11040598 Lmr5b_m leishmaniasis resistance 5b (mouse) 10 105179713 130530862 Mouse
