M1ap (meiosis 1 associated protein) - Rat Genome Database
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Gene: M1ap (meiosis 1 associated protein) Mus musculus
Analyze
Symbol: M1ap
Name: meiosis 1 associated protein
RGD ID: 1620665
MGI Page MGI
Description: Is expressed in reproductive system. Human ortholog(s) of this gene implicated in spermatogenic failure 48. Orthologous to human M1AP (meiosis 1 associated protein); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D6Mm5e; hypothetical protein LOC110958; meiosis 1 arrest protein; meiosis 1-arresting protein; meiosis 1-associated protein; spermatogenesis-associated protein 37; uncharacterized protein C2orf65 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39682,923,889 - 83,007,290 (+)NCBIGRCm39mm39
GRCm39 Ensembl682,923,883 - 83,007,290 (+)Ensembl
GRCm38682,946,908 - 83,030,309 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl682,946,902 - 83,030,309 (+)EnsemblGRCm38mm10GRCm38
MGSCv37682,896,916 - 82,980,303 (+)NCBIGRCm37mm9NCBIm37
MGSCv36682,922,067 - 82,995,825 (+)NCBImm8
Celera684,923,693 - 85,011,817 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9806835   PMID:9927484   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466305   PMID:12466851   PMID:12477932   PMID:12520002   PMID:16141072  
PMID:16141073   PMID:16881047   PMID:18287559   PMID:21408140   PMID:21873635   PMID:22844512   PMID:23269666   PMID:32673564  


Genomics

Comparative Map Data
M1ap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39682,923,889 - 83,007,290 (+)NCBIGRCm39mm39
GRCm39 Ensembl682,923,883 - 83,007,290 (+)Ensembl
GRCm38682,946,908 - 83,030,309 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl682,946,902 - 83,030,309 (+)EnsemblGRCm38mm10GRCm38
MGSCv37682,896,916 - 82,980,303 (+)NCBIGRCm37mm9NCBIm37
MGSCv36682,922,067 - 82,995,825 (+)NCBImm8
Celera684,923,693 - 85,011,817 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
M1AP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl274,557,883 - 74,648,338 (-)EnsemblGRCh38hg38GRCh38
GRCh38274,557,640 - 74,648,330 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37274,785,010 - 74,875,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,638,518 - 74,728,672 (-)NCBINCBI36hg18NCBI36
Celera274,616,118 - 74,706,273 (-)NCBI
Cytogenetic Map2p13.1NCBI
HuRef274,521,271 - 74,612,923 (-)NCBIHuRef
CHM1_1274,714,405 - 74,804,858 (-)NCBICHM1_1
M1ap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24115,445,910 - 115,536,745 (+)NCBI
Rnor_6.0 Ensembl4113,782,206 - 113,863,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04113,772,716 - 113,864,171 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04178,458,149 - 178,548,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,149,673 - 117,241,780 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4104,441,328 - 104,532,093 (+)NCBICelera
Cytogenetic Map4q34NCBI
M1ap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,157,812 - 11,232,677 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,155,239 - 11,232,880 (+)NCBIChiLan1.0ChiLan1.0
M1AP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A76,130,507 - 76,220,738 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A76,130,507 - 76,220,738 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A74,624,522 - 74,715,353 (-)NCBIMhudiblu_PPA_v0panPan3
M1AP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1748,510,094 - 48,587,547 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11748,510,569 - 48,588,589 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
M1ap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936556770,269 - 861,509 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
M1AP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl368,417,915 - 68,494,421 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1368,411,968 - 68,494,666 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,585,448 - 71,666,498 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103220013
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,630,651 - 32,719,884 (+)NCBI
ChlSab1.1 Ensembl1432,637,838 - 32,719,061 (+)Ensembl
M1ap
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474928,855,225 - 28,955,378 (+)NCBI

Position Markers
14.MMHAP63FRE8.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,005,514 - 83,005,704UniSTSGRCm38
MGSCv37682,955,508 - 82,955,698UniSTSGRCm37
Celera684,986,068 - 84,986,258UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.7UniSTS
Whitehead_YAC6 UniSTS
D6Mit189  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38682,985,330 - 82,985,480UniSTSGRCm38
MGSCv37682,935,324 - 82,935,474UniSTSGRCm37
Celera684,962,049 - 84,962,199UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.97UniSTS
Whitehead Genetic624.0UniSTS
Whitehead_YAC6 UniSTS
D6UmiJ16  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38682,968,302 - 82,968,462UniSTSGRCm38
MGSCv37682,918,296 - 82,918,456UniSTSGRCm37
Celera684,945,054 - 84,945,214UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.68UniSTS
D6UmiJ18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,012,200 - 83,012,353UniSTSGRCm38
MGSCv37682,962,194 - 82,962,347UniSTSGRCm37
Celera684,992,761 - 84,993,780UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.69UniSTS
D6UmiJ19  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,028,842 - 83,028,968UniSTSGRCm38
MGSCv37682,978,836 - 82,978,962UniSTSGRCm37
Cytogenetic Map6C3UniSTS
cM Map634.7UniSTS
D6Umi1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,015,288 - 83,015,448UniSTSGRCm38
MGSCv37682,965,282 - 82,965,442UniSTSGRCm37
Celera684,996,718 - 84,996,878UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.71UniSTS
cM Map634.65UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:523
Count of miRNA genes:379
Interacting mature miRNAs:409
Transcripts:ENSMUST00000113980, ENSMUST00000144906
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000113980   ⟹   ENSMUSP00000109613
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl682,946,902 - 83,030,183 (+)Ensembl
RefSeq Acc Id: ENSMUST00000144906
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,028,251 - 83,029,823 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204891   ⟹   ENSMUSP00000144948
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,026,338 - 83,030,309 (+)Ensembl
RefSeq Acc Id: NM_033079   ⟹   NP_149070
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,923,903 - 83,007,290 (+)NCBI
GRCm38682,946,922 - 83,030,309 (+)NCBI
MGSCv37682,896,916 - 82,980,303 (+)RGD
Celera684,923,693 - 85,011,817 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505368   ⟹   XP_006505431
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,923,889 - 83,007,163 (+)NCBI
GRCm38682,946,908 - 83,030,182 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505369   ⟹   XP_006505432
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,982,127 - 83,007,163 (+)NCBI
GRCm38683,005,101 - 83,030,182 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241141   ⟹   XP_011239443
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,938,091 - 83,007,163 (+)NCBI
GRCm38682,961,110 - 83,030,182 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_149070   ⟸   NM_033079
- UniProtKB: Q9Z0E1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006505431   ⟸   XM_006505368
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006505432   ⟸   XM_006505369
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011239443   ⟸   XM_011241141
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000109613   ⟸   ENSMUST00000113980
RefSeq Acc Id: ENSMUSP00000144948   ⟸   ENSMUST00000204891

Promoters
RGD ID:6890102
Promoter ID:EPDNEW_M8501
Type:multiple initiation site
Name:M1ap_2
Description:Mus musculus meiosis 1 associated protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8502  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38682,946,922 - 82,946,982EPDNEW
RGD ID:6890104
Promoter ID:EPDNEW_M8502
Type:multiple initiation site
Name:M1ap_1
Description:Mus musculus meiosis 1 associated protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8501  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38682,952,747 - 82,952,807EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1315200 AgrOrtholog
Ensembl Genes ENSMUSG00000030041 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000109613 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144948 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000113980 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000204891 UniProtKB/TrEMBL
InterPro M1AP UniProtKB/Swiss-Prot
KEGG Report mmu:110958 UniProtKB/Swiss-Prot
MGD MGI:1315200 ENTREZGENE
NCBI Gene 110958 ENTREZGENE
PANTHER PTHR28642 UniProtKB/Swiss-Prot
PhenoGen M1ap PhenoGen
UniProt A0A0N4SV45_MOUSE UniProtKB/TrEMBL
  M1AP_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3V2A0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-12 M1ap  meiosis 1 associated protein  D6Mm5e  DNA segment, Chr 6, Miriam Meisler 5, expressed  Symbol and/or name change 5135510 APPROVED