M1ap (meiosis 1 associated protein) - Rat Genome Database
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Gene: M1ap (meiosis 1 associated protein) Mus musculus
Analyze
Symbol: M1ap
Name: meiosis 1 associated protein
RGD ID: 1620665
MGI Page MGI
Description: Is expressed in reproductive system. Human ortholog(s) of this gene implicated in spermatogenic failure 48. Orthologous to human M1AP (meiosis 1 associated protein); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D6Mm5e; hypothetical protein LOC110958; meiosis 1 arrest protein; meiosis 1-arresting protein; meiosis 1-associated protein; spermatogenesis-associated protein 37; uncharacterized protein C2orf65 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39682,923,889 - 83,007,290 (+)NCBIGRCm39mm39
GRCm39 Ensembl682,923,883 - 83,007,290 (+)Ensembl
GRCm38682,946,908 - 83,030,309 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl682,946,902 - 83,030,309 (+)EnsemblGRCm38mm10GRCm38
MGSCv37682,896,916 - 82,980,303 (+)NCBIGRCm37mm9NCBIm37
MGSCv36682,922,067 - 82,995,825 (+)NCBImm8
Celera684,923,693 - 85,011,817 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:9806835   PMID:9927484   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11125038   PMID:11217851   PMID:12466305   PMID:12466851   PMID:12477932   PMID:12520002   PMID:16141072  
PMID:16141073   PMID:16881047   PMID:18287559   PMID:21408140   PMID:21873635   PMID:22844512   PMID:23269666   PMID:32673564  


Genomics

Comparative Map Data
M1ap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39682,923,889 - 83,007,290 (+)NCBIGRCm39mm39
GRCm39 Ensembl682,923,883 - 83,007,290 (+)Ensembl
GRCm38682,946,908 - 83,030,309 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl682,946,902 - 83,030,309 (+)EnsemblGRCm38mm10GRCm38
MGSCv37682,896,916 - 82,980,303 (+)NCBIGRCm37mm9NCBIm37
MGSCv36682,922,067 - 82,995,825 (+)NCBImm8
Celera684,923,693 - 85,011,817 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
M1AP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl274,557,883 - 74,648,338 (-)EnsemblGRCh38hg38GRCh38
GRCh38274,557,640 - 74,648,330 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37274,785,010 - 74,875,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,638,518 - 74,728,672 (-)NCBINCBI36hg18NCBI36
Celera274,616,118 - 74,706,273 (-)NCBI
Cytogenetic Map2p13.1NCBI
HuRef274,521,271 - 74,612,923 (-)NCBIHuRef
CHM1_1274,714,405 - 74,804,858 (-)NCBICHM1_1
M1ap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24115,445,910 - 115,536,745 (+)NCBI
Rnor_6.0 Ensembl4113,782,206 - 113,863,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04113,772,716 - 113,864,171 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04178,458,149 - 178,548,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,149,673 - 117,241,780 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4104,441,328 - 104,532,093 (+)NCBICelera
Cytogenetic Map4q34NCBI
M1ap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,157,812 - 11,232,677 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,155,239 - 11,232,880 (+)NCBIChiLan1.0ChiLan1.0
M1AP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A76,130,507 - 76,220,738 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A76,130,507 - 76,220,738 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A74,624,522 - 74,715,353 (-)NCBIMhudiblu_PPA_v0panPan3
M1AP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1748,510,094 - 48,587,547 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11748,510,569 - 48,588,589 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
M1ap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936556770,269 - 861,509 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
M1AP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl368,417,915 - 68,494,421 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1368,411,968 - 68,494,666 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,585,448 - 71,666,498 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103220013
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,630,651 - 32,719,884 (+)NCBI
ChlSab1.1 Ensembl1432,637,838 - 32,719,061 (+)Ensembl
M1ap
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474928,855,225 - 28,955,378 (+)NCBI

Position Markers
14.MMHAP63FRE8.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,005,514 - 83,005,704UniSTSGRCm38
MGSCv37682,955,508 - 82,955,698UniSTSGRCm37
Celera684,986,068 - 84,986,258UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.7UniSTS
Whitehead_YAC6 UniSTS
D6Mit189  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38682,985,330 - 82,985,480UniSTSGRCm38
MGSCv37682,935,324 - 82,935,474UniSTSGRCm37
Celera684,962,049 - 84,962,199UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.97UniSTS
Whitehead Genetic624.0UniSTS
Whitehead_YAC6 UniSTS
D6UmiJ16  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38682,968,302 - 82,968,462UniSTSGRCm38
MGSCv37682,918,296 - 82,918,456UniSTSGRCm37
Celera684,945,054 - 84,945,214UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.68UniSTS
D6UmiJ18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,012,200 - 83,012,353UniSTSGRCm38
MGSCv37682,962,194 - 82,962,347UniSTSGRCm37
Celera684,992,761 - 84,993,780UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.69UniSTS
D6UmiJ19  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,028,842 - 83,028,968UniSTSGRCm38
MGSCv37682,978,836 - 82,978,962UniSTSGRCm37
Cytogenetic Map6C3UniSTS
cM Map634.7UniSTS
D6Umi1a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38683,015,288 - 83,015,448UniSTSGRCm38
MGSCv37682,965,282 - 82,965,442UniSTSGRCm37
Celera684,996,718 - 84,996,878UniSTS
Cytogenetic Map6C3UniSTS
cM Map634.71UniSTS
cM Map634.65UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:523
Count of miRNA genes:379
Interacting mature miRNAs:409
Transcripts:ENSMUST00000113980, ENSMUST00000144906
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000113980   ⟹   ENSMUSP00000109613
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl682,946,902 - 83,030,183 (+)Ensembl
RefSeq Acc Id: ENSMUST00000144906
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,028,251 - 83,029,823 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204891   ⟹   ENSMUSP00000144948
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,026,338 - 83,030,309 (+)Ensembl
RefSeq Acc Id: NM_033079   ⟹   NP_149070
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,923,903 - 83,007,290 (+)NCBI
GRCm38682,946,922 - 83,030,309 (+)NCBI
MGSCv37682,896,916 - 82,980,303 (+)RGD
Celera684,923,693 - 85,011,817 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505368   ⟹   XP_006505431
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,923,889 - 83,007,163 (+)NCBI
GRCm38682,946,908 - 83,030,182 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505369   ⟹   XP_006505432
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,982,127 - 83,007,163 (+)NCBI
GRCm38683,005,101 - 83,030,182 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241141   ⟹   XP_011239443
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,938,091 - 83,007,163 (+)NCBI
GRCm38682,961,110 - 83,030,182 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_149070   ⟸   NM_033079
- UniProtKB: Q9Z0E1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006505431   ⟸   XM_006505368
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006505432   ⟸   XM_006505369
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011239443   ⟸   XM_011241141
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000109613   ⟸   ENSMUST00000113980
RefSeq Acc Id: ENSMUSP00000144948   ⟸   ENSMUST00000204891

Promoters
RGD ID:6890102
Promoter ID:EPDNEW_M8501
Type:multiple initiation site
Name:M1ap_2
Description:Mus musculus meiosis 1 associated protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8502  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38682,946,922 - 82,946,982EPDNEW
RGD ID:6890104
Promoter ID:EPDNEW_M8502
Type:multiple initiation site
Name:M1ap_1
Description:Mus musculus meiosis 1 associated protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8501  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38682,952,747 - 82,952,807EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1315200 AgrOrtholog
Ensembl Genes ENSMUSG00000030041 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000109613 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000144948 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000113980 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000204891 UniProtKB/TrEMBL
InterPro M1AP UniProtKB/Swiss-Prot
KEGG Report mmu:110958 UniProtKB/Swiss-Prot
MGD MGI:1315200 ENTREZGENE
NCBI Gene 110958 ENTREZGENE
PANTHER PTHR28642 UniProtKB/Swiss-Prot
PhenoGen M1ap PhenoGen
UniProt A0A0N4SV45_MOUSE UniProtKB/TrEMBL
  M1AP_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3V2A0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-12 M1ap  meiosis 1 associated protein  D6Mm5e  DNA segment, Chr 6, Miriam Meisler 5, expressed  Symbol and/or name change 5135510 APPROVED