Psg28 (pregnancy-specific beta-1-glycoprotein 28) - Rat Genome Database

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Gene: Psg28 (pregnancy-specific beta-1-glycoprotein 28) Mus musculus
Analyze
No known orthologs.
Symbol: Psg28
Name: pregnancy-specific beta-1-glycoprotein 28
RGD ID: 1620662
MGI Page MGI
Description: Predicted to be involved in T cell activation. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Is expressed in labyrinthine zone. Orthologous to human CEACAM7 (CEA cell adhesion molecule 7) and PSG5 (pregnancy specific beta-1-glycoprotein 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cea16; MGC117566; MGC117567; pregnancy-specific glycoprotein 28
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,156,461 - 18,165,980 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,156,461 - 18,165,966 (-)EnsemblGRCm39 Ensembl
GRCm38718,422,536 - 18,432,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl718,422,536 - 18,432,041 (-)EnsemblGRCm38mm10GRCm38
MGSCv37719,007,885 - 19,017,404 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36717,581,063 - 17,590,563 (-)NCBIMGSCv36mm8
Celera715,847,982 - 15,857,501 (-)NCBICelera
Cytogenetic Map7A2NCBI
cM Map79.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21119013   PMID:21267068   PMID:21873635  


Genomics

Variants

.
Variants in Psg28
258 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:72
Interacting mature miRNAs:72
Transcripts:ENSMUST00000019291
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301177Vent3_mventricular size 3 (mouse)Not determined7120511925Mouse
10054067Sle20_msystematic lupus erythematosus susceptibility 20 (mouse)Not determined7120511925Mouse
1302188Lxw6_mlupus BXSB x NZW 6 (mouse)Not determined7121698146Mouse
12904941Edlmmq6_mextensor digitorum longus muscle mass QTL 6 (mouse)7121821047Mouse
12904948Tammq5_mtibialis anterior muscle mass QTL 5 (mouse)7121821047Mouse
12904953Gmmq5_mgastrocnemius muscle mass QTL 5 (mouse)7121821047Mouse
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1301115Lrdm1_mlymphoproliferation (Fas) renal disease modifier 1 (mouse)Not determined7335204824879418Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000019291   ⟹   ENSMUSP00000019291
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl718,156,461 - 18,165,966 (-)Ensembl
GRCm38.p6 Ensembl718,422,536 - 18,432,041 (-)Ensembl
RefSeq Acc Id: NM_054063   ⟹   NP_473404
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39718,156,461 - 18,165,980 (-)NCBI
GRCm38718,422,536 - 18,432,055 (-)ENTREZGENE
MGSCv37719,007,885 - 19,017,404 (-)RGD
Celera715,847,982 - 15,857,501 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_473404 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD39363 (Get FASTA)   NCBI Sequence Viewer  
  AAH99402 (Get FASTA)   NCBI Sequence Viewer  
  AAH99403 (Get FASTA)   NCBI Sequence Viewer  
  AAI41039 (Get FASTA)   NCBI Sequence Viewer  
  CAA73898 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000019291
  ENSMUSP00000019291.6
Reference Protein Sequences
RefSeq Acc Id: NP_473404   ⟸   NM_054063
- UniProtKB: Q4KL66 (UniProtKB/TrEMBL),   Q4KL67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000019291   ⟸   ENSMUST00000019291
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KL66-F1-model_v2 AlphaFold Q4KL66 1-472 view protein structure

Promoters
RGD ID:6891986
Promoter ID:EPDNEW_M9444
Type:multiple initiation site
Name:Psg28_1
Description:Mus musculus pregnancy-specific glycoprotein 28 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38718,432,061 - 18,432,121EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891360 AgrOrtholog
Ensembl Genes ENSMUSG00000030373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000019291 ENTREZGENE
  ENSMUST00000019291.7 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
KEGG Report mmu:114871 UniProtKB/TrEMBL
MGD MGI:1891360 ENTREZGENE
NCBI Gene 114871 ENTREZGENE
PANTHER CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 21 UniProtKB/TrEMBL
  CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 21 UniProtKB/TrEMBL
  SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE UniProtKB/TrEMBL
Pfam Ig_3 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Psg28 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt Q4KL66 ENTREZGENE, UniProtKB/TrEMBL
  Q4KL67 ENTREZGENE, UniProtKB/TrEMBL
  Q9WVH7_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-14 Psg28  pregnancy-specific beta-1-glycoprotein 28  Psg28  pregnancy-specific glycoprotein 28  Symbol and/or name change 5135510 APPROVED