H1f10 (H1.10 linker histone) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: H1f10 (H1.10 linker histone) Mus musculus
Analyze
Symbol: H1f10
Name: H1.10 linker histone
RGD ID: 1620558
MGI Page MGI
Description: Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and spinal cord. Orthologous to human H1-10 (H1.10 linker histone).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Gm461; H1 histone family, member X; H1-10; H1.10; H1fx; H1X
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,957,403 - 87,958,464 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,957,403 - 87,958,619 (-)Ensembl
GRCm38687,980,421 - 87,981,482 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,980,421 - 87,981,637 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,930,415 - 87,931,476 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,946,062 - 87,947,123 (-)NCBImm8
Celera689,917,433 - 89,918,305 (-)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:18799693   PMID:18973680   PMID:19389796   PMID:19710015   PMID:21267068   PMID:21873635   PMID:22650316   PMID:24194600   PMID:26689747   PMID:27626380  
PMID:28700664   PMID:28766996   PMID:28794128  


Genomics

Comparative Map Data
H1f10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,957,403 - 87,958,464 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,957,403 - 87,958,619 (-)Ensembl
GRCm38687,980,421 - 87,981,482 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,980,421 - 87,981,637 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,930,415 - 87,931,476 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,946,062 - 87,947,123 (-)NCBImm8
Celera689,917,433 - 89,918,305 (-)NCBICelera
Cytogenetic Map6D1NCBI
H1-10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3129,314,771 - 129,316,286 (-)EnsemblGRCh38hg38GRCh38
GRCh383129,314,771 - 129,316,286 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373129,033,614 - 129,035,129 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,516,305 - 130,517,807 (-)NCBINCBI36hg18NCBI36
Build 343130,516,312 - 130,517,815NCBI
Celera3127,464,821 - 127,466,328 (-)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3126,418,569 - 126,420,075 (-)NCBIHuRef
CHM1_13128,996,883 - 128,998,389 (-)NCBICHM1_1
H1f10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24120,440,515 - 120,444,705 (-)NCBI
Rnor_6.0 Ensembl4119,889,371 - 119,889,949 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04119,889,016 - 119,892,661 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04185,136,727 - 185,140,194 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44122,179,764 - 122,180,823 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4109,399,957 - 109,403,602 (-)NCBICelera
Cytogenetic Map4q34NCBI
LOC102012785
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542913,672,008 - 13,672,613 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542913,671,907 - 13,673,689 (-)NCBIChiLan1.0ChiLan1.0
LOC117979756
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v03126,375,743 - 126,377,467 (-)NCBIMhudiblu_PPA_v0panPan3
H1-10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1202,799,360 - 2,800,524 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
LOC100516295
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11371,760,464 - 71,762,035 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21379,433,152 - 79,434,216 (-)NCBISscrofa10.2Sscrofa10.2susScr3
H1FX
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12251,749,560 - 51,751,081 (+)NCBI
ChlSab1.1 Ensembl2251,749,948 - 51,750,586 (+)Ensembl


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:239
Count of miRNA genes:178
Interacting mature miRNAs:194
Transcripts:ENSMUST00000056403
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000056403   ⟹   ENSMUSP00000060761
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,980,421 - 87,981,637 (-)Ensembl
RefSeq Acc Id: NM_198622   ⟹   NP_941024
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,957,403 - 87,958,464 (-)NCBI
GRCm38687,980,421 - 87,981,482 (-)ENTREZGENE
MGSCv37687,930,415 - 87,931,476 (-)RGD
Celera689,917,433 - 89,918,305 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_941024 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH48709 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_941024   ⟸   NM_198622
- UniProtKB: Q80ZM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000060761   ⟸   ENSMUST00000056403
Protein Domains
H15

Promoters
RGD ID:6839899
Promoter ID:MM_KWN:46798
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:NM_198622,   OTTMUST00000060578,   XR_034267_GM10249
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36687,929,996 - 87,930,817 (+)MPROMDB
RGD ID:6890358
Promoter ID:EPDNEW_M8630
Type:initiation region
Name:H1fx_1
Description:Mus musculus H1 histone family, member X , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38687,981,388 - 87,981,448EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685307 AgrOrtholog
Ensembl Genes ENSMUSG00000044927 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000060761 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000056403 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro Histone_H1/H5 UniProtKB/TrEMBL
  Histone_H5 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report mmu:243529 UniProtKB/TrEMBL
MGD MGI:2685307 ENTREZGENE
NCBI Gene 243529 ENTREZGENE
Pfam Linker_histone UniProtKB/TrEMBL
PhenoGen H1f10 PhenoGen
PRINTS HISTONEH5 UniProtKB/TrEMBL
PROSITE H15 UniProtKB/TrEMBL
SMART H15 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt Q80ZM5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-13 H1f10  H1.10 linker histone  H1fx  H1 histone family, member X  Symbol and/or name change 5135510 APPROVED