Vasn (vasorin) - Rat Genome Database
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Gene: Vasn (vasorin) Mus musculus
Analyze
Symbol: Vasn
Name: vasorin
RGD ID: 1620549
MGI Page MGI
Description: Predicted to have transforming growth factor beta binding activity. Involved in cellular response to hypoxia and cellular response to redox state. Localizes to mitochondrion and plasma membrane. Is expressed in several structures, including cardiovascular system; cranium; embryo mesenchyme; genitourinary system; and gut. Orthologous to human VASN (vasorin); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610528G05Rik; A; Atia; Sl; Slit-like 2; Slitl2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,457,809 - 4,469,030 (+)NCBIGRCm39mm39
GRCm38164,639,945 - 4,651,166 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,639,941 - 4,650,802 (+)EnsemblGRCm38mm10GRCm38
MGSCv37164,639,945 - 4,651,166 (+)NCBIGRCm37mm9NCBIm37
MGSCv36164,555,222 - 4,566,010 (+)NCBImm8
Celera165,269,412 - 5,281,840 (+)NCBICelera
Cytogenetic Map16A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15247411   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:21267068   PMID:21658601   PMID:21873635   PMID:22426063   PMID:22967998   PMID:25826454   PMID:29259033   PMID:32325033  


Genomics

Comparative Map Data
Vasn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,457,809 - 4,469,030 (+)NCBIGRCm39mm39
GRCm38164,639,945 - 4,651,166 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,639,941 - 4,650,802 (+)EnsemblGRCm38mm10GRCm38
MGSCv37164,639,945 - 4,651,166 (+)NCBIGRCm37mm9NCBIm37
MGSCv36164,555,222 - 4,566,010 (+)NCBImm8
Celera165,269,412 - 5,281,840 (+)NCBICelera
Cytogenetic Map16A1NCBI
VASN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl164,371,848 - 4,383,538 (+)EnsemblGRCh38hg38GRCh38
GRCh38164,371,848 - 4,383,538 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37164,421,849 - 4,433,529 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,361,850 - 4,373,530 (+)NCBINCBI36hg18NCBI36
Celera164,630,756 - 4,642,436 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef164,389,019 - 4,400,698 (+)NCBIHuRef
CHM1_1164,421,602 - 4,433,268 (+)NCBICHM1_1
Vasn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01011,121,041 - 11,131,548 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1011,121,041 - 11,131,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,886,399 - 9,896,906 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41011,047,084 - 11,057,591 (-)NCBIRGSC3.4rn4RGSC3.4
Celera109,880,012 - 9,890,519 (-)NCBICelera
Cytogenetic Map10q12NCBI
Vasn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544213,060,923 - 13,071,303 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544213,060,923 - 13,071,303 (-)NCBIChiLan1.0ChiLan1.0
VASN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1164,466,452 - 4,478,154 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,475,506 - 4,477,527 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0163,298,836 - 3,310,548 (+)NCBIMhudiblu_PPA_v0panPan3
VASN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl637,015,333 - 37,017,351 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1637,014,704 - 37,025,734 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Vasn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936694128,398 - 138,954 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VASN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl337,961,425 - 37,972,115 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1337,961,425 - 37,972,477 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2339,016,527 - 39,029,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VASN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,052,239 - 4,063,884 (+)NCBI
Vasn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248242,154,646 - 2,164,796 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120963024Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122682710Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122702454Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16123079875Mouse
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124445989Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124445989Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128616494Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129856336Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130249113Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130996708Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16350000040000000Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16350000051600000Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16350000064800000Mouse
1302106Rapop1_mradiation-induced apoptosis 1 (mouse)Not determined16396291515913189Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16400000064800000Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16450000044700000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:399
Count of miRNA genes:333
Interacting mature miRNAs:368
Transcripts:ENSMUST00000038770, ENSMUST00000138044
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000038770   ⟹   ENSMUSP00000045162
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl164,639,941 - 4,650,802 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138044
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl164,639,968 - 4,647,559 (+)Ensembl
RefSeq Acc Id: NM_139307   ⟹   NP_647468
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39164,457,809 - 4,469,030 (+)NCBI
GRCm38164,639,945 - 4,651,166 (+)ENTREZGENE
MGSCv37164,639,945 - 4,651,166 (+)RGD
Celera165,269,412 - 5,281,840 (+)RGD
cM Map16 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_647468   ⟸   NM_139307
- Peptide Label: precursor
- UniProtKB: Q9CZT5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000045162   ⟸   ENSMUST00000038770
Protein Domains
EGF-like   Fibronectin type-III   LRRCT   LRRNT

Promoters
RGD ID:6827657
Promoter ID:MM_KWN:19979
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:AK052973_D930006K15RIK,   ENSMUST00000038770,   OTTMUST00000059744,   OTTMUST00000060756
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36164,637,846 - 4,640,647 (+)MPROMDB
RGD ID:8685332
Promoter ID:EPDNEW_M20697
Type:multiple initiation site
Name:Vasn_1
Description:Mus musculus vasorin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38164,639,968 - 4,640,028EPDNEW
RGD ID:6827621
Promoter ID:MM_KWN:19981
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000115855
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36164,647,221 - 4,650,162 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2177651 AgrOrtholog
Ensembl Genes ENSMUSG00000039646 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000045162 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000038770 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Leu-rich_rpt UniProtKB/Swiss-Prot
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
KEGG Report mmu:246154 UniProtKB/Swiss-Prot
MGD MGI:2177651 ENTREZGENE
NCBI Gene 246154 ENTREZGENE
Pfam EGF UniProtKB/Swiss-Prot
  fn3 UniProtKB/Swiss-Prot
  LRR_8 UniProtKB/Swiss-Prot
PhenoGen Vasn PhenoGen
PROSITE EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  LRR UniProtKB/Swiss-Prot
SMART EGF UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  LRR_TYP UniProtKB/Swiss-Prot
  LRRCT UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot
UniProt Q9CZT5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8BJJ0 UniProtKB/Swiss-Prot
  Q8R2G5 UniProtKB/Swiss-Prot