Gm1527 (predicted gene 1527) - Rat Genome Database

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Gene: Gm1527 (predicted gene 1527) Mus musculus
Analyze
No known orthologs.
Symbol: Gm1527
Name: predicted gene 1527
RGD ID: 1620414
MGI Page MGI
Description: Predicted to enable GTPase activator activity.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: gene model 1136, (NCBI); Gm1136; hypothetical protein LOC385263; uncharacterized protein LOC385263
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39328,946,768 - 28,980,874 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl328,946,766 - 28,980,873 (+)EnsemblGRCm39 Ensembl
GRCm38328,892,619 - 28,926,725 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl328,892,617 - 28,926,724 (+)EnsemblGRCm38mm10GRCm38
MGSCv37328,791,539 - 28,825,646 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36329,083,690 - 29,117,797 (+)NCBIMGSCv36mm8
Cytogenetic Map3A3NCBI
cM Map312.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:16141072   PMID:16141073   PMID:21873635  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:75
Interacting mature miRNAs:76
Transcripts:ENSMUST00000099170
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32017486254180103Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
12904010Cfq8_mconditioned fear QTL 8 (mouse)32476823231332103Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1828816852288168Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3452541938525519Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31163045345630591Mouse

Markers in Region
UniSTS:225387  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38331,684,584 - 31,684,732UniSTSGRCm38
GRCm38328,898,515 - 28,898,663UniSTSGRCm38
MGSCv37331,583,506 - 31,583,654UniSTSGRCm37
MGSCv37328,797,437 - 28,797,585UniSTSGRCm37
Celera331,586,787 - 31,586,935UniSTS
Cytogenetic Map3A3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000099170   ⟹   ENSMUSP00000096773
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,946,766 - 28,980,873 (+)Ensembl
GRCm38.p6 Ensembl328,892,617 - 28,926,724 (+)Ensembl
RefSeq Acc Id: NM_001033479   ⟹   NP_001028651
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,946,768 - 28,980,874 (+)NCBI
GRCm38328,892,619 - 28,926,725 (+)NCBI
MGSCv37328,791,539 - 28,825,646 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017319633   ⟹   XP_017175122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,949,690 - 28,980,874 (+)NCBI
GRCm38328,895,541 - 28,926,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017319634   ⟹   XP_017175123
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,957,543 - 28,980,868 (+)NCBI
GRCm38328,903,394 - 28,926,719 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030252663   ⟹   XP_030108523
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,949,690 - 28,980,868 (+)NCBI
GRCm38328,895,541 - 28,926,719 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030252664   ⟹   XP_030108524
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,949,690 - 28,980,677 (+)NCBI
GRCm38328,895,541 - 28,926,528 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030252665   ⟹   XP_030108525
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,949,690 - 28,980,663 (+)NCBI
GRCm38328,895,541 - 28,926,514 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163149   ⟹   XP_036019042
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,949,690 - 28,975,875 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001028651   ⟸   NM_001033479
- UniProtKB: Q3V0P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017175122   ⟸   XM_017319633
- Peptide Label: isoform X2
- UniProtKB: Q3V0P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017175123   ⟸   XM_017319634
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_030108523   ⟸   XM_030252663
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030108524   ⟸   XM_030252664
- Peptide Label: isoform X3
RefSeq Acc Id: XP_030108525   ⟸   XM_030252665
- Peptide Label: isoform X3
Ensembl Acc Id: ENSMUSP00000096773   ⟸   ENSMUST00000099170
RefSeq Acc Id: XP_036019042   ⟸   XM_036163149
- Peptide Label: isoform X3
Protein Domains
Ras-associating   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3V0P3-F1-model_v2 AlphaFold Q3V0P3 1-650 view protein structure

Promoters
RGD ID:6880388
Promoter ID:EPDNEW_M3645
Type:initiation region
Name:Gm1527_1
Description:Mus musculus predicted gene 1527 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38328,892,619 - 28,892,679EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2686373 AgrOrtholog
Ensembl Genes ENSMUSG00000074655 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099170 ENTREZGENE
  ENSMUST00000099170.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro ARHGAP20_PH UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Ras-assoc UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
KEGG Report mmu:385263 UniProtKB/TrEMBL
MGD MGI:2686373 ENTREZGENE
NCBI Gene 385263 ENTREZGENE
PANTHER GENE 1527-RELATED UniProtKB/TrEMBL
  T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED UniProtKB/TrEMBL
Pfam PF00788 UniProtKB/TrEMBL
  RHG20_PH UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PhenoGen Gm1527 PhenoGen
PROSITE PS50200 UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  Rho_GAP UniProtKB/TrEMBL
UniProt Q3V0P3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-02 Gm1527  predicted gene 1527  Gm1136  gene model 1136, (NCBI)  Data merged from RGD:1614611 737654 PROVISIONAL