Prr23a1 (proline rich 23A, member 1) - Rat Genome Database

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Gene: Prr23a1 (proline rich 23A, member 1) Mus musculus
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Symbol: Prr23a1
Name: proline rich 23A, member 1
RGD ID: 1620312
MGI Page MGI
Description: Is expressed in face. Orthologous to several human genes including PRR23C (proline rich 23C).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EG623166; Gm6400; Pr; proline rich 23A; Prr23a
RGD Orthologs
Human
Rat
Bonobo
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,724,640 - 98,725,698 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,724,556 - 98,725,438 (+)EnsemblGRCm39 Ensembl
GRCm38998,842,587 - 98,843,645 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,842,503 - 98,843,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,743,006 - 98,744,064 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,651,939 - 98,652,715 (+)NCBIMGSCv36mm8
Celera998,375,164 - 98,376,222 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:24565867  


Genomics

Comparative Map Data
Prr23a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39998,724,640 - 98,725,698 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl998,724,556 - 98,725,438 (+)EnsemblGRCm39 Ensembl
GRCm38998,842,587 - 98,843,645 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl998,842,503 - 98,843,385 (+)EnsemblGRCm38mm10GRCm38
MGSCv37998,743,006 - 98,744,064 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36998,651,939 - 98,652,715 (+)NCBIMGSCv36mm8
Celera998,375,164 - 98,376,222 (+)NCBICelera
Cytogenetic Map9E3.3NCBI
cM Map951.41NCBI
PRR23C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383139,042,102 - 139,044,892 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3139,042,102 - 139,044,892 (-)EnsemblGRCh38hg38GRCh38
GRCh373138,760,944 - 138,763,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363140,245,364 - 140,246,418 (-)NCBINCBI36Build 36hg18NCBI36
Celera3137,187,214 - 137,190,001 (-)NCBICelera
Cytogenetic Map3q23NCBI
HuRef3136,136,298 - 136,139,085 (-)NCBIHuRef
CHM1_13138,725,238 - 138,728,025 (-)NCBICHM1_1
T2T-CHM13v2.03141,783,116 - 141,785,903 (-)NCBIT2T-CHM13v2.0
Prr23a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88108,303,959 - 108,304,747 (+)NCBIGRCr8
mRatBN7.2899,424,574 - 99,425,362 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl899,424,574 - 99,425,362 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.08107,106,972 - 107,107,892 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8107,106,982 - 107,129,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08106,531,927 - 106,532,998 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera898,830,133 - 98,830,931 (+)NCBICelera
Cytogenetic Map8q31NCBI
PRR23C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22136,951,315 - 136,955,018 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13136,956,044 - 136,960,109 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03136,074,879 - 136,078,681 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13143,676,488 - 143,677,150 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3143,676,488 - 143,677,217 (-)Ensemblpanpan1.1panPan2
LOC110256523
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11379,795,592 - 79,797,974 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in Prr23a1
47 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:125
Count of miRNA genes:120
Interacting mature miRNAs:124
Transcripts:ENSMUST00000170349
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966089077100089175Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967006220101006220Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968779563102779705Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968779563102779705Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969121898103121973Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969428566103428698Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976024387101406120Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000170349   ⟹   ENSMUSP00000127711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl998,724,556 - 98,725,438 (+)Ensembl
GRCm38.p6 Ensembl998,842,503 - 98,843,385 (+)Ensembl
RefSeq Acc Id: NM_001134660   ⟹   NP_001128132
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39998,724,640 - 98,725,698 (+)NCBI
GRCm38998,842,587 - 98,843,645 (+)ENTREZGENE
MGSCv37998,743,006 - 98,744,064 (+)RGD
Celera998,375,164 - 98,376,222 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001128132 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL20990 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000127711
  ENSMUSP00000127711.2
Reference Protein Sequences
RefSeq Acc Id: NP_001128132   ⟸   NM_001134660
- UniProtKB: G3UW32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000127711   ⟸   ENSMUST00000170349

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3UW32-F1-model_v2 AlphaFold G3UW32 1-258 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3645743 AgrOrtholog
Ensembl Genes ENSMUSG00000091080 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000170349 ENTREZGENE
  ENSMUST00000170349.3 UniProtKB/TrEMBL
InterPro UPF0572 UniProtKB/TrEMBL
KEGG Report mmu:623166 UniProtKB/TrEMBL
MGD MGI:3645743 ENTREZGENE
NCBI Gene 623166 ENTREZGENE
PANTHER PROLINE-RICH PROTEIN 23A UniProtKB/TrEMBL
  PROLINE-RICH PROTEIN 23B UniProtKB/TrEMBL
Pfam DUF2476 UniProtKB/TrEMBL
PhenoGen Prr23a1 PhenoGen
UniProt G3UW32 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-23 Prr23a1  proline rich 23A, member 1  Prr23a  proline rich 23A  Symbol and/or name change 5135510 APPROVED