Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of CCDC69 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of CCDC69 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCDC69 mRNA | CTD | PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCDC69 mRNA | CTD | PMID:32109520 | 2-hydroxypropanoic acid | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of CCDC69 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CCDC69 mRNA | CTD | PMID:30071829 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC69 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of CCDC69 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of CCDC69 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of CCDC69 mRNA | CTD | PMID:24780913 | acetamide | increases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of CCDC69 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of CCDC69 mRNA | CTD | PMID:27153756 | arsenite(3-) | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to CCDC69 mRNA] | CTD | PMID:32406909 | belinostat | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | belinostat results in increased expression of CCDC69 mRNA | CTD | PMID:26272509 | belinostat | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC69 mRNA | CTD | PMID:27188386 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CCDC69 mRNA | CTD | PMID:21932408 | bisphenol A | affects expression | ISO | CCDC69 (Homo sapiens) | 6480464 | bisphenol A affects the expression of CCDC69 mRNA | CTD | PMID:30903817 | bisphenol A | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC69 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of CCDC69 mRNA | CTD | PMID:25181051 and PMID:31129395 | chlordecone | increases expression | EXP | | 6480464 | Chlordecone results in increased expression of CCDC69 mRNA | CTD | PMID:33711761 | cisplatin | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of CCDC69 mRNA | CTD | PMID:27392435 and PMID:27594783 | cisplatin | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of CCDC69 mRNA | CTD | PMID:27392435 | copper(II) sulfate | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of CCDC69 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of CCDC69 mRNA | CTD | PMID:20106945 and PMID:25562108 | dexamethasone | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Dexamethasone results in increased expression of CCDC69 mRNA | CTD | PMID:25047013 | dexamethasone | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC69 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of CCDC69 mRNA | CTD | PMID:28628672 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of CCDC69 mRNA | CTD | PMID:21266533 | disodium selenite | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of CCDC69 mRNA | CTD | PMID:18175754 | diuron | increases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | Diuron results in increased expression of CCDC69 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CCDC69 mRNA | CTD | PMID:29803840 | entinostat | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC69 mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | entinostat results in increased expression of CCDC69 mRNA | CTD | PMID:26272509 and PMID:27188386 | folic acid | increases expression | EXP | | 6480464 | Folic Acid results in increased expression of CCDC69 mRNA | CTD | PMID:25629700 | genistein | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Genistein results in increased expression of CCDC69 mRNA | CTD | PMID:20884965 | gentamycin | increases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of CCDC69 mRNA | CTD | PMID:22061828 and PMID:33387578 | hydrogen cyanide | decreases expression | EXP | | 6480464 | Hydrogen Cyanide results in decreased expression of CCDC69 mRNA | CTD | PMID:33914522 | indometacin | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CCDC69 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of CCDC69 mRNA | CTD | PMID:28628672 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of CCDC69 mRNA | CTD | PMID:19751817 | lidocaine | increases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | Lidocaine results in increased expression of CCDC69 mRNA | CTD | PMID:35283115 | methyl methanesulfonate | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of CCDC69 mRNA | CTD | PMID:23649840 | panobinostat | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | panobinostat results in increased expression of CCDC69 mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC69 mRNA | CTD | PMID:27188386 | perfluorohexanesulfonic acid | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of CCDC69 mRNA | CTD | PMID:25812627 | perfluorononanoic acid | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of CCDC69 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CCDC69 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of CCDC69 mRNA | CTD | PMID:25812627 | phenylmercury acetate | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of CCDC69 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC69 mRNA | CTD | PMID:27188386 | potassium cyanide | decreases expression | EXP | | 6480464 | Potassium Cyanide results in decreased expression of CCDC69 mRNA | CTD | PMID:33914522 | quercetin | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of CCDC69 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of CCDC69 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of CCDC69 mRNA | CTD | PMID:25895662 | sodium arsenite | affects expression | ISO | CCDC69 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of CCDC69 mRNA | CTD | PMID:34032870 | sunitinib | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of CCDC69 mRNA | CTD | PMID:31533062 | thioacetamide | increases expression | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of CCDC69 mRNA | CTD | PMID:34492290 | trichostatin A | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of CCDC69 mRNA | CTD | PMID:24935251 | triclosan | decreases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of CCDC69 mRNA | CTD | PMID:30510588 | valproic acid | affects expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CCDC69 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | CCDC69 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CCDC69 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | CCDC69 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC69 mRNA | CTD | PMID:27188386 | vinclozolin | increases methylation | ISO | Ccdc69 (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of CCDC69 gene | CTD | PMID:31682807 | |