Naa80 (N(alpha)-acetyltransferase 80, NatH catalytic subunit) - Rat Genome Database
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Gene: Naa80 (N(alpha)-acetyltransferase 80, NatH catalytic subunit) Mus musculus
Analyze
Symbol: Naa80
Name: N(alpha)-acetyltransferase 80, NatH catalytic subunit
RGD ID: 1620066
MGI Page MGI
Description: Predicted to have acetyl-CoA binding activity and peptide alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation; actin modification; and regulation of actin polymerization or depolymerization. Predicted to localize to cytosol. Is expressed in heart ventricle; liver; and metanephros. Orthologous to human NAA80 (N-alpha-acetyltransferase 80, NatH catalytic subunit); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI225910; Fus2; fusion 2; N-acetyltransferase 6; N-alpha-acetyltransferase 80; Na; Nat6; protein fus-2; protein fusion-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,457,868 - 107,461,247 (+)NCBIGRCm39mm39
GRCm389107,580,669 - 107,584,048 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,578,887 - 107,584,050 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,482,501 - 107,486,379 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,438,269 - 107,442,149 (+)NCBImm8
Celera9107,188,942 - 107,192,827 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (ISO)

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11085536   PMID:11217851   PMID:11929860   PMID:12466851   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:18772348   PMID:21267068   PMID:21677750   PMID:21873635  


Genomics

Comparative Map Data
Naa80
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,457,868 - 107,461,247 (+)NCBIGRCm39mm39
GRCm389107,580,669 - 107,584,048 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,578,887 - 107,584,050 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,482,501 - 107,486,379 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,438,269 - 107,442,149 (+)NCBImm8
Celera9107,188,942 - 107,192,827 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.18NCBI
NAA80
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl350,296,402 - 50,299,416 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl350,296,402 - 50,299,421 (-)EnsemblGRCh38hg38GRCh38
GRCh38350,296,402 - 50,299,405 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37350,333,833 - 50,336,852 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,308,837 - 50,311,716 (-)NCBINCBI36hg18NCBI36
Build 34350,308,837 - 50,311,716NCBI
Celera350,306,664 - 50,309,543 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef350,389,576 - 50,392,595 (-)NCBIHuRef
CHM1_1350,286,139 - 50,289,158 (-)NCBICHM1_1
Naa80
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08116,336,441 - 116,339,691 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,336,441 - 116,339,690 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08115,692,701 - 115,695,951 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera8107,560,892 - 107,564,142 (+)NCBICelera
Cytogenetic Map8q32NCBI
Naa80
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555322,109,595 - 2,112,013 (-)NCBIChiLan1.0ChiLan1.0
NAA80
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1351,459,748 - 51,462,764 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl351,459,748 - 51,462,764 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0350,225,000 - 50,228,015 (-)NCBIMhudiblu_PPA_v0panPan3
NAA80
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,042,078 - 39,044,894 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Naa80
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365291,834,308 - 1,837,248 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAA80
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,793,569 - 32,800,796 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,793,784 - 32,794,650 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,972,319 - 35,973,185 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap13q21NCBI
NAA80
(Chlorocebus sabaeus - African green monkey)		 No map positions available.
Naa80
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247304,157,714 - 4,159,927 (-)NCBI

Position Markers
RH136004  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,580,692 - 107,580,886UniSTSGRCm38
MGSCv379107,483,023 - 107,483,217UniSTSGRCm37
Celera9107,189,464 - 107,189,658UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map9F1-F2UniSTS
cM Map960.15UniSTS
AF011567  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,579,432 - 107,579,565UniSTSGRCm38
MGSCv379107,481,763 - 107,481,896UniSTSGRCm37
Celera9107,188,201 - 107,188,334UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map9F1-F2UniSTS
cM Map960.15UniSTS
Whitehead/MRC_RH91108.16UniSTS
Hyal1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,578,418 - 107,578,898UniSTSGRCm38
MGSCv379107,480,749 - 107,481,229UniSTSGRCm37
Celera9107,187,191 - 107,187,667UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map9F1-F2UniSTS
cM Map960.1UniSTS
Nat6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9F1UniSTS
cM Map960.15UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959990000109260000Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974368177108368325Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976535936110536130Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985897510108641186Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1337
Count of miRNA genes:291
Interacting mature miRNAs:334
Transcripts:ENSMUST00000093785, ENSMUST00000122985, ENSMUST00000127380, ENSMUST00000130053, ENSMUST00000139274, ENSMUST00000139581, ENSMUST00000149638
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000093785   ⟹   ENSMUSP00000091300
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,580,117 - 107,584,050 (+)Ensembl
RefSeq Acc Id: ENSMUST00000122985   ⟹   ENSMUSP00000122807
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,578,887 - 107,583,519 (+)Ensembl
RefSeq Acc Id: ENSMUST00000127380   ⟹   ENSMUSP00000116378
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,578,887 - 107,583,519 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130053   ⟹   ENSMUSP00000114490
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,578,887 - 107,583,519 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139274   ⟹   ENSMUSP00000138933
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,578,887 - 107,583,519 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139581   ⟹   ENSMUSP00000122321
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,578,887 - 107,583,519 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149638   ⟹   ENSMUSP00000139004
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9107,578,887 - 107,583,519 (+)Ensembl
RefSeq Acc Id: NM_019750   ⟹   NP_062724
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,457,868 - 107,461,247 (+)NCBI
GRCm389107,580,669 - 107,584,048 (+)NCBI
MGSCv379107,482,501 - 107,486,379 (+)RGD
Celera9107,188,942 - 107,192,827 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_062724   ⟸   NM_019750
- UniProtKB: Q9R123 (UniProtKB/Swiss-Prot),   Q3UVC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000114490   ⟸   ENSMUST00000130053
RefSeq Acc Id: ENSMUSP00000122321   ⟸   ENSMUST00000139581
RefSeq Acc Id: ENSMUSP00000138933   ⟸   ENSMUST00000139274
RefSeq Acc Id: ENSMUSP00000116378   ⟸   ENSMUST00000127380
RefSeq Acc Id: ENSMUSP00000091300   ⟸   ENSMUST00000093785
RefSeq Acc Id: ENSMUSP00000139004   ⟸   ENSMUST00000149638
RefSeq Acc Id: ENSMUSP00000122807   ⟸   ENSMUST00000122985
Protein Domains
N-acetyltransferase

Promoters
RGD ID:6844680
Promoter ID:MM_KWN:58726
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000040059,   OTTMUST00000071422,   OTTMUST00000072297,   OTTMUST00000085813,   UC009RLX.1,   UC009RLY.1,   UC009RLZ.1,   UC009RMA.1,   UC009RMB.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369107,480,446 - 107,483,162 (+)MPROMDB
RGD ID:8670806
Promoter ID:EPDNEW_M13433
Type:initiation region
Name:Nat6_1
Description:Mus musculus N-acetyltransferase 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389107,580,774 - 107,580,834EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1888902 AgrOrtholog
Ensembl Genes ENSMUSG00000079334 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000091300 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000114490 UniProtKB/TrEMBL
  ENSMUSP00000116378 UniProtKB/TrEMBL
  ENSMUSP00000122321 UniProtKB/TrEMBL
  ENSMUSP00000122807 UniProtKB/TrEMBL
  ENSMUSP00000138933 UniProtKB/TrEMBL
  ENSMUSP00000139004 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000093785 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000122985 UniProtKB/TrEMBL
  ENSMUST00000127380 UniProtKB/TrEMBL
  ENSMUST00000130053 UniProtKB/TrEMBL
  ENSMUST00000139274 UniProtKB/TrEMBL
  ENSMUST00000139581 UniProtKB/TrEMBL
  ENSMUST00000149638 UniProtKB/TrEMBL
InterPro Acyl_CoA_acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GNAT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAA80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56441 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1888902 ENTREZGENE
NCBI Gene 56441 ENTREZGENE
PANTHER PTHR13538:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Acetyltransf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Naa80 PhenoGen
PROSITE GNAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55729 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.10305 ENTREZGENE
  Mm.475658 ENTREZGENE
UniProt A0A0R4J2B1_MOUSE UniProtKB/TrEMBL
  B7ZCE0_MOUSE UniProtKB/TrEMBL
  NAA80_MOUSE UniProtKB/Swiss-Prot
  Q3UVC9 ENTREZGENE, UniProtKB/TrEMBL
  Q9R123 ENTREZGENE
UniProt Secondary Q8QZY5 UniProtKB/Swiss-Prot
  Q8R014 UniProtKB/Swiss-Prot
  Q9ERM0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-14 Naa80  N(alpha)-acetyltransferase 80, NatH catalytic subunit  Nat6  N-acetyltransferase 6  Symbol and/or name change 5135510 APPROVED