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Gene: Cul4a (cullin 4A) Mus musculus
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Symbol: Cul4a
Name: cullin 4A
Description: Predicted to have ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of granulocyte differentiation; positive regulation of G1/S transition of mitotic cell cycle; and regulation of response to DNA damage stimulus. Predicted to localize to the Cul4A-RING E3 ubiquitin ligase complex and SCF ubiquitin ligase complex. Is expressed in brain; liver; lung; metanephros; and spleen. Orthologous to human CUL4A (cullin 4A); PARTICIPATES IN nucleotide excision repair pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810470J21Rik; AW495282; CUL-4A; cullin-4A; MGC36573
Orthologs:
Homo sapiens (human) : CUL4A (cullin 4A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cul4a (cullin 4A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul4a (cullin 4A)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL4A (cullin 4A)
Canis lupus familiaris (dog) : CUL4A (cullin 4A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul4a (cullin 4A)
Sus scrofa (pig) : CUL4A (cullin 4A)
more info ...
Related Pseudogenes: Gm9410  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl813,105,621 - 13,147,940 (+)Ensembl
GRCm38813,105,623 - 13,147,940 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37813,105,721 - 13,147,940 (+)NCBIGRCm37mm9NCBIm37
MGSCv36813,105,720 - 13,147,753 (+)NCBImm8
Celera813,272,636 - 13,315,964 (+)NCBICelera
Cytogenetic Map8 A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cul4a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1619917
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.