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Gene: Cul4a (cullin 4A) Mus musculus
Symbol: Cul4a
Name: cullin 4A
Description: Predicted to have ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of granulocyte differentiation; positive regulation of G1/S transition of mitotic cell cycle; and regulation of response to DNA damage stimulus. Predicted to localize to the Cul4A-RING E3 ubiquitin ligase complex and SCF ubiquitin ligase complex. Is expressed in brain; liver; lung; metanephros; and spleen. Orthologous to human CUL4A (cullin 4A); PARTICIPATES IN nucleotide excision repair pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810470J21Rik; AW495282; CUL-4A; cullin-4A; MGC36573
Homo sapiens (human) : CUL4A (cullin 4A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cul4a (cullin 4A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul4a (cullin 4A)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL4A (cullin 4A)
Canis lupus familiaris (dog) : CUL4A (cullin 4A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul4a (cullin 4A)
Sus scrofa (pig) : CUL4A (cullin 4A)
more info ...
Related Pseudogenes: Gm9410  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl813,105,621 - 13,147,940 (+)Ensembl
GRCm38813,105,623 - 13,147,940 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37813,105,721 - 13,147,940 (+)NCBIGRCm37mm9NCBIm37
MGSCv36813,105,720 - 13,147,753 (+)NCBImm8
Celera813,272,636 - 13,315,964 (+)NCBICelera
Cytogenetic Map8 A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cul4a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1619917
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.