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Gene: Cyp2c50 (cytochrome P450, family 2, subfamily c, polypeptide 50) Mus musculus
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Symbol: Cyp2c50
Name: cytochrome P450, family 2, subfamily c, polypeptide 50
Description: Exhibits arachidonic acid epoxygenase activity and linoleic acid epoxygenase activity. Involved in arachidonic acid metabolic process and linoleic acid metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including eosinophilic esophagitis; glucose metabolism disease (multiple); hypertension; multiple myeloma; and sickle cell anemia. Is expressed in alimentary system and liver. Orthologous to human CYP2C19 (cytochrome P450 family 2 subfamily C member 19) and CYP2C9 (cytochrome P450 family 2 subfamily C member 9); PARTICIPATES IN forkhead class A signaling pathway; arachidonic acid metabolic pathway; linoleic acid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxytolbutamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI266900; CYPIIC50; cytochrome P450 2C50; cytochrome P450, 2c50
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1940,089,688 - 40,113,950 (+)Ensembl
GRCm381940,089,679 - 40,113,955 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371940,164,169 - 40,188,445 (+)NCBIGRCm37mm9NCBIm37
MGSCv361940,143,007 - 40,167,262 (+)NCBImm8
Celera1940,883,277 - 40,906,411 (+)NCBICelera
Cytogenetic Map19 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cyp2c50
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1619904
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.