Abhd12b (abhydrolase domain containing 12B)

Gene: Abhd12b (abhydrolase domain containing 12B) Mus musculus

Analyze

Symbol:

Abhd12b

Name:

abhydrolase domain containing 12B

RGD ID:

1619703

MGI Page

MGI

Description:

Predicted to enable acylglycerol lipase activity and lysophospholipase activity. Predicted to be involved in monoacylglycerol catabolic process and phosphatidylserine catabolic process. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ABHD12B (abhydrolase domain containing 12B).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

abhydrolase domain-containing protein 12B; Gm804

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ABHD12B (abhydrolase domain containing 12B)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Rattus norvegicus (Norway rat):	Abhd12b (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Abhd12b (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ABHD12B (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ABHD12B (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Abhd12b (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ABHD12B (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ABHD12B (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Abhd12b (abhydrolase domain containing 12B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Abhd12b (abhydrolase domain containing 12B)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ABHD12B (abhydrolase domain containing 12B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-117n7.7	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	si:ch211-117n7.6	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG15111	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	abhd-12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	abhd12b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	70,200,898 - 70,236,870 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	70,200,916 - 70,230,661 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	70,154,124 - 70,190,096 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	70,154,142 - 70,183,887 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	71,255,158 - 71,284,193 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	71,255,158 - 71,284,193 (+)	NCBI		MGSCv36	mm8
Celera	12	71,262,816 - 71,284,636 (+)	NCBI		Celera
Cytogenetic Map	12	C2	NCBI
cM Map	12	28.96	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2-hydroxypropanoic acid (ISO)

3-phenylprop-2-enal (ISO)

5-fluorouracil (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (EXP)

bisphenol A (ISO)

diarsenic trioxide (ISO)

folic acid (EXP)

fonofos (ISO)

ozone (EXP)

parathion (ISO)

perfluorohexanesulfonic acid (EXP)

rac-lactic acid (ISO)

sodium arsenate (ISO)

terbufos (ISO)

triclosan (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

monoacylglycerol catabolic process (IBA)

phosphatidylserine catabolic process (IBA)

Cellular Component

endoplasmic reticulum membrane (IBA)

Molecular Function

acylglycerol lipase activity (IBA)

lysophospholipase activity (IBA)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased fasting circulating glucose level (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:16141072	PMID:16141073	PMID:21873635

Genomics

Comparative Map Data

Abhd12b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	70,200,898 - 70,236,870 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	70,200,916 - 70,230,661 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	70,154,124 - 70,190,096 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	70,154,142 - 70,183,887 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	71,255,158 - 71,284,193 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	71,255,158 - 71,284,193 (+)	NCBI		MGSCv36	mm8
Celera	12	71,262,816 - 71,284,636 (+)	NCBI		Celera
Cytogenetic Map	12	C2	NCBI
cM Map	12	28.96	NCBI

ABHD12B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	50,872,053 - 50,904,970 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	50,872,053 - 50,904,970 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	51,338,771 - 51,371,688 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	50,408,628 - 50,441,438 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	50,408,627 - 50,441,438	NCBI
Celera	14	31,205,922 - 31,238,736 (+)	NCBI		Celera
Cytogenetic Map	14	q22.1	NCBI
HuRef	14	31,464,434 - 31,497,262 (+)	NCBI		HuRef
CHM1_1	14	51,277,383 - 51,310,199 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	45,078,480 - 45,111,409 (+)	NCBI		T2T-CHM13v2.0

Abhd12b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	94,404,594 - 94,432,395 (+)	NCBI		GRCr8
mRatBN7.2	6	88,668,627 - 88,696,435 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	88,668,642 - 88,696,458 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	89,067,929 - 89,095,671 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	89,367,386 - 89,395,122 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	88,806,908 - 88,834,654 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	92,568,975 - 92,596,327 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	92,568,975 - 92,596,327 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	102,016,360 - 102,043,712 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	92,270,150 - 92,296,907 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	92,279,609 - 92,300,363 (+)	NCBI
Celera	6	87,163,225 - 87,190,437 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

Abhd12b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	12,007,989 - 12,037,005 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	12,007,471 - 12,036,999 (-)	NCBI	ChiLan1.0	ChiLan1.0

ABHD12B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	52,004,502 - 52,042,222 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	51,221,027 - 51,258,729 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	31,459,836 - 31,494,138 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	49,760,119 - 49,792,963 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	49,760,119 - 49,792,963 (+)	Ensembl	panpan1.1		panPan2

ABHD12B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	27,239,900 - 27,264,615 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	27,240,153 - 27,264,680 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	26,987,414 - 27,019,452 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	27,412,696 - 27,445,173 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	27,419,001 - 27,450,036 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	27,067,340 - 27,100,295 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	27,140,675 - 27,172,972 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	27,485,290 - 27,520,417 (+)	NCBI		UU_Cfam_GSD_1.0

Abhd12b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	59,438,210 - 59,462,680 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936495	14,729,594 - 14,753,102 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936495	14,728,885 - 14,753,188 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABHD12B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	180,639,898 - 180,661,065 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	180,635,479 - 180,662,432 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	200,922,668 - 200,949,737 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABHD12B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	27,952,072 - 27,987,645 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	27,953,124 - 27,987,443 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	16,250,498 - 16,283,625 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abhd12b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	18,029,116 - 18,058,081 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	18,028,573 - 18,058,331 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Abhd12b
1502 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1000
Count of miRNA genes:	291
Interacting mature miRNAs:	319
Transcripts:	ENSMUST00000161541, ENSMUST00000162570, ENSMUST00000169156, ENSMUST00000182512, ENSMUST00000182782, ENSMUST00000182927
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142234	Tmc1m3_m	Tmc1 modifier 3 (mouse)			Not determined		12	5418440	77031203	Mouse
27226753	Femd7_m	femur midshaft diameter 7, 10 week (mouse)					12	9550000	84146774	Mouse
13207568	Tcq14_m	total cholesterol QTL 14 (mouse)					12	11660001	97176774	Mouse
1558978	Cplaq10_m	circadian period of locomotor activity 10 (mouse)			Not determined		12	15341026	79040364	Mouse
1301574	Lmblgq5_m	limb length QTL 5 (mouse)			Not determined		12	17596447	80956883	Mouse
4142002	Tbqt3_m	tibia bone quality traits 3 (mouse)			Not determined		12	35285496	109936243	Mouse
1357479	Splwt1_m	spleen weight 1 (mouse)			Not determined		12	41693175	90887526	Mouse
1357757	Lnopy2_m	lens opacity 2 (mouse)			Not determined		12	52846626	86846796	Mouse
1357749	Vtbt13_m	vertebral trabecular bone trait 13 (mouse)			Not determined		12	53132002	87132145	Mouse
12832727	Ahrq1_m	airway hyperresponsiveness QTL 1 (mouse)					12	54695910	82665939	Mouse
13504832	Bacszq2_m	baculum size QTL 2 (mouse)					12	56945798	75345787	Mouse
27226728	Tibl20_m	tibia length 20, 16 week (mouse)					12	59146786	93866774	Mouse
27226776	Tibl6_m	tibia length 6, 5 week (mouse)					12	60646786	92666774	Mouse
10043948	Pbft6_m	percent body fat 6 (mouse)			Not determined		12	61205427	95205427	Mouse
1301476	Pbwg12_m	postnatal body weight growth 12 (mouse)			Not determined		12	62040164	96040364	Mouse
27226797	Scvln19_m	sacral vertebrae length 2, 16 week (mouse)					12	62146786	99466259	Mouse
10043895	Bw20_m	body weight QTL 20 (mouse)			Not determined		12	62308252	96308252	Mouse
1301046	Par3_m	pulmonary adenoma resistance 3 (mouse)			Not determined		12	63956708	97956883	Mouse
1301337	Cdcs8_m	cytokine deficiency colitis susceptibility 8 (mouse)			Not determined		12	64689083	98689229	Mouse
1300633	Cdcs7_m	cytokine deficiency colitis susceptibility 7 (mouse)			Not determined		12	64689083	98689229	Mouse
14746976	Manh73_m	mandible shape 73 (mouse)					12	65857131	99857131	Mouse
27226771	Tibl14_m	tibia length 14, 10 week (mouse)					12	68346774	98766259	Mouse
27226793	Feml10_m	femur length 10, 5 week (mouse)					12	68346774	113363620	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001195033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_030246486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC112146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK136846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000161541

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	70,228,822 - 70,230,121 (+)	Ensembl
GRCm38.p6 Ensembl	12	70,182,048 - 70,183,347 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000162570

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	70,200,916 - 70,230,121 (+)	Ensembl
GRCm38.p6 Ensembl	12	70,154,142 - 70,183,347 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000169156 ⟹ ENSMUSP00000134568

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	70,200,931 - 70,230,661 (+)	Ensembl
GRCm38.p6 Ensembl	12	70,154,157 - 70,183,887 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000182512 ⟹ ENSMUSP00000138185

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	70,200,931 - 70,230,661 (+)	Ensembl
GRCm38.p6 Ensembl	12	70,154,157 - 70,183,887 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000182782 ⟹ ENSMUSP00000138423

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	70,200,931 - 70,230,661 (+)	Ensembl
GRCm38.p6 Ensembl	12	70,154,157 - 70,183,887 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000182927 ⟹ ENSMUSP00000138681

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	70,200,931 - 70,230,661 (+)	Ensembl
GRCm38.p6 Ensembl	12	70,154,157 - 70,183,887 (+)	Ensembl

RefSeq Acc Id:

NM_001195033 ⟹ NP_001181962

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	12	70,200,905 - 70,230,121 (+)	NCBI
GRCm38	12	70,154,131 - 70,183,347 (+)	NCBI
Celera	12	71,260,718 - 71,284,634 (+)	ENTREZGENE
cM Map	12		ENTREZGENE

Sequence:

show sequence

AAGCCTGTGGCAGCTCCCTCAGCAGTGGAGGCACCTCAGGATGGACGCTAGGGACTGTGATGCA
GCCTCGGAGCCAGGGCCCCCTCCCTGTTCCTCTGTGACCTCCTGGTGGGCTATGGTCCTGAGGA
ACCTGAGGCTTTTCCCATGCTTCTGCTCAGCGCTCGGGAGTAAAATAGCTGCCGAGTACAGAAA
CTTCACGAGTAAATCTTTAAAGGAACACATTTTCCCTCCGCTGATGAATATGCTGATATATTTA
AATTGCATTACGGCTCCCATTCTCGTGGATTTAAAGAGACCAGAGACAAAGATTGCTCACACAG
TGAACTTCTTCCTCAAGCCTGAACCCAAGGTTCTGCTTGGCATCTGGCACACAGTCCCCAGCTA
CCGGGGAGAAGAGGCCAAGGGGAAGTGTCGATGCTGGTACGAAGCCTCCCTCAGTGATGGGAAC
CCGATTATTATCTATCTTCATGGCAGTGGGATAAACAGGGCATTTTGTGGAAGAATTAAGCTGA
CACAGGTGCTGAGTGATGGCGGCTTCCATGTATTGTCTGTGGACTATAGAGGATTTGGAGATTC
TACAGGAACAACTACAGAGGAGGGACTAACCACAGACATTATTTGTGTCTATGAATGGACCAAG
GCAAGAAGTGGTAGAACTCCTGTGTGTCTGTGGGGCCATTCTCTGGGAACAGGAGTTGCAACAA
ATGCTGCAAGAGTCCTAGAAGCAAAAGGATGTCCAGTTGATGCTATTATCTTAGAAGCTCCATT
TACCAACATATGGGCAGCAACTATCAATTTTCCCTTGGTAAAGATGTACTGGAAGCTTCCAGGA
TGTTTAAGAACGTTTGTGGATGCCCTTAAAGAAGAGAAAATAGTCTTTCCTAACGATGAAAATG
TGAAGTTTCTGTCCTCCCCGCTTCTCATCTTGCATGGTGAAGACGACAGGACGGTGCCTCTGGA
GTTCGGAAAGCAGCTCTATGAAATTGCACGCAGTGCCTACAGGAACAAAGAGAGGGTCAAAATG
GTCGTCTTTCCTCCTGGCTTCCATCACGACTATCTCTTTAAGAGCCCCATGCTGTTAAGTACTG
TGAGAGACTTCCTGAGCGAGCAGTGGGCATAAAAGGCTGGGACCAGCAGAAATTTCCAGTGAAG
ATGTGGTTCAAACCTTGCCTGAGCTGGGTGGTTTCTTTATGCAAAATTGTGCTGGGATGCTTGG
ATGAGCTGAAGCTCACCCGACATTTGAATAAACAAAGCTGCATGG

hide sequence

RefSeq Acc Id:

XM_030246486 ⟹ XP_030102346

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	12	70,200,898 - 70,236,870 (+)	NCBI
GRCm38	12	70,154,124 - 70,190,096 (+)	NCBI

Sequence:

show sequence

TCCCTGGAAGCCTGTGGCAGCTCCCTCAGCAGTGGAGGCACCTCAGGATGGACGCTAGGGACTG
TGATGCAGCCTCGGAGCCAGGGCCCCCTCCCTGTTCCTCTGTGACCTCCTGGTGGGCTATGGTC
CTGAGGAACCTGAGGCTTTTCCCATGCTTCTGCTCAGCGCTCGGGAGTAAAATAGCTGCCGAGT
ACAGAAACTTCACGAGTAAATCTTTAAAGGAACACATTTTCCCTCCGCTGATGAATATGCTGAT
ATATTTAAATTGCATTACGGCTCCCATTCTCGTGGATTTAAAGAGACCAGAGACAAAGATTGCT
CACACAGTGAACTTCTTCCTCAAGCCTGAACCCAAGGTTCTGCTTGGCATCTGGCACACAGTCC
CCAGCTACCGGGGAGAAGAGGCCAAGGGGAAGTGTCGATGCTGGTACGAAGCCTCCCTCAGTGA
TGGGAACCCGATTATTATCTATCTTCATGGCAGTGGGATAAACAGGGCATTTTGTGGAAGAATT
AAGCTGACACAGGTGCTGAGTGATGGCGGCTTCCATGTATTGTCTGTGGACTATAGAGGATTTG
GAGATTCTACAGGAACAACTACAGAGGAGGGACTAACCACAGACATTATTTGTGTCTATGAATG
GACCAAGGCAAGAAGTGGTAGAACTCCTGTGTGTCTGTGGGGCCATTCTCTGGGAACAGGAGTT
GCAACAAATGCTGCAAGAGTCCTAGAAGCAAAAGGATGTCCAGTTGATGCTATTATCTTAGAAG
CTCCATTTACCAACATATGGGCAGCAACTATCAATTTTCCCTTGGTAAAGATGTACTGGAAGCT
TCCAGGATGTTTAAGAACGTTTGTGGATGCCCTTAAAGAAGAGAAAATAGTCTTTCCTAACGAT
GAAAATGTGAAGTTTCTGTCCTCCCCGCTTCTCATCTTGCATGGTGAAGACGACAGGACGGTGC
CTCTGGAGTTCGGAAAGCAGCTCTATGAAATTGCACGCAGTGCCTACAGGAACAAAGAGAGGGT
CAAAATGGTCGTCTTTCCTCCTGGCTTCCATCACGACTATCTCTTTAAGAGCCCCATGCTGTTA
AGTACTGTGAGAGACTTCCTGAGCGAGCAGTGGGCATAAAAGGCTGGGACCAGCAGAAATTTCC
AGTGAAGATGTGGTTCAAACCTTGCCTGAGCTGGGTGGTTTCTTTATGCAAAATTGTGCTGGGA
TGCTTGGATGAGCTGAAGCTCACCCGACATTTGAATAAACAAAGCTGCATGGAATGTTCTTTAG
TCCATCATTGTCTGAGAATCATGCCAAATCTTCAACGTGGAGAATCAGAATCTAATGTGATCTG
ATCTCATCTATAAATGCCCACCTACGAACCCTGCTGGGATATTTGTGAGTAAGGTGAATGCTGG
TACATGAACTCAGTGTCTGCCCCCAAGCTCCTAGGTTAAAATTTACCTGTCAGCGTGATGGTAT
CAGGAGGCAGAGGCTTTCAAAGGTGGTGTGAGCCGGGCTCTTGGGGATGAAATTAGGTCCCCAA
AACACAGATCTAAAGGAGTGTGGAGAGCTGCAATAACATTTACCATCATAAGATGGTGCCGACT
TCCACAGTGCCTTATGCCACCTAAACAAAGATCAAGCTGTGTGCGCATGTGCAAGGAGTAAAAG
CGCACCAAGTCACTAGCCCACCCCCAGGGCGTGTATATGAGATCATGGGTAAGCAACCATTCAG
GCGAGGACACGCCACACCAGGGGGTATATAAGCAGCCCCTTTTCTGAGGCTCTTGGTCTTCCTC
ATCAATATGTAATAAAGATTGGCTGCAGAAGGATCCTTATGTCCCGTGTGCGTTCCTGTGGGCG
AGAACAATAGCATGGGACATATGGCGCCGAGAACCCGGGAAAAATACCACACCATCACCCAGTG
CCGAGGAGGCCCTCCGCTCCGTGGAGAGGATCCAGAACTGTAGCATGAAAGGGTGAAGAAAATC
CACTTTGGGTCTCAATGCGACTGATAAGGACCGTGAAAGATACAGATCTATCGAATTATCTGAA
GGGGAACTGGTTGCAGAAGCTAGGTTGCAGACGAAGCTGCAGATACAGATCCTGAACCAGAGTG
GAACCAGTGACCCTTGGAGACTTCACCTCTTGGCTTACCTCTGCATTTTTCTTACTTCAAAGAA
TGGCTGGGGGGGGGGGGAAATCTGTTTGGCACAGCCTTGTGTTGTGGATTAGTGTTCATGCTAT
GGTTGGTCTGCAAGCTCAGATCTCAACAGAAACGTGACAAGGTTGTGATAGCTCAAGCACTTGC
TGCCATAGAGCAAGGGGCCTCCCCTAAAATTTGGTTATCTATTCTCAAGAATTAGTCAGCATCT
GAGTTCTCTGCTTTTGCATCCCACGGATTTGTGGATCCATTGCACTGGGATGAGAGAGATTCAA
CGATCATTGATCAGCCCTTGCACATCACTGAGGTTTCCTCTTGCACGTGATAGGGTGATCATGA
TTTCCCTATTAATTCATTTTTTGGCTGGCCTCGCTTGTAGAGTTCGCCCTAGGTCATTTAGCAG
TTACTGTCACACAGTACTGCGGTATCCAGAGACGGGCAACTTTCCTCATGCACAGACCAACCTA
AGACACGGGGCCCAGTGGCGATAGGGTTACCCTATGATGGGTAAGGCTGTGACATTAGAGGAAC
GGCCTAAAACAGGAGCCACAGCAGATGGACATAACTGCAGAGGCCTAGACCAGCCTCGTTTTAA
TAATATATAAGGGGGGGGGGGAGATGTGGAGAGCCGCAATAACATTTACCATCATAAGATGGTG
CCGGCTTCCACAGTGCCTTAATGCCACCTAAACAAAGATCAAGCTGTGTGCGCATGTGCAAGGA
GTAAAAGCGCACCAAGTCACTAGCCCACCCCCGGGGCATGTATATGAGATCATGGGTAAGCAAC
CATTCAGGCGTGGACACGCCACACCAGGGGGTATATAAGCAGCCCCTTTTCTGAGGCTCTTGGT
CTTCCTCATCAATATGTAATAAAGATTGGCTGCAGAAGGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001181962	(Get FASTA)	NCBI Sequence Viewer
	XP_030102346	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000134568
	ENSMUSP00000134568.2
	ENSMUSP00000138185.2
	ENSMUSP00000138423.2
	ENSMUSP00000138681.2

RefSeq Acc Id:

NP_001181962 ⟸ NM_001195033

- UniProtKB:

G3UZN6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDARDCDAASEPGPPPCSSVTSWWAMVLRNLRLFPCFCSALGSKIAAEYRNFTSKSLKEHIFPP
LMNMLIYLNCITAPILVDLKRPETKIAHTVNFFLKPEPKVLLGIWHTVPSYRGEEAKGKCRCWY
EASLSDGNPIIIYLHGSGINRAFCGRIKLTQVLSDGGFHVLSVDYRGFGDSTGTTTEEGLTTDI
ICVYEWTKARSGRTPVCLWGHSLGTGVATNAARVLEAKGCPVDAIILEAPFTNIWAATINFPLV
KMYWKLPGCLRTFVDALKEEKIVFPNDENVKFLSSPLLILHGEDDRTVPLEFGKQLYEIARSAY
RNKERVKMVVFPPGFHHDYLFKSPMLLSTVRDFLSEQWA

hide sequence

RefSeq Acc Id:	XP_030102346 ⟸ XM_030246486
- Peptide Label:	isoform X1
- UniProtKB:	G3UZN6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSMUSP00000138423 ⟸ ENSMUST00000182782

RefSeq Acc Id:

ENSMUSP00000138681 ⟸ ENSMUST00000182927

RefSeq Acc Id:

ENSMUSP00000134568 ⟸ ENSMUST00000169156

RefSeq Acc Id:

ENSMUSP00000138185 ⟸ ENSMUST00000182512

Protein Domains

Serine aminopeptidase S33

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3UZN6-F1-model_v2	AlphaFold	G3UZN6	1-359	view protein structure

Promoters

RGD ID:

8678442

Promoter ID:

EPDNEW_M17252

Type:

multiple initiation site

Name:

Abhd12b_1

Description:

Mus musculus abhydrolase domain containing 12B , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	12	70,154,151 - 70,154,211	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2685650	AgrOrtholog
Ensembl Genes	ENSMUSG00000090121	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000169156	ENTREZGENE
	ENSMUST00000169156.3	UniProtKB/TrEMBL
	ENSMUST00000182512.8	UniProtKB/TrEMBL
	ENSMUST00000182782.8	UniProtKB/TrEMBL
	ENSMUST00000182927.8	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	Hydrolase_4	UniProtKB/TrEMBL
KEGG Report	mmu:100504285	UniProtKB/TrEMBL
MGD	MGI:2685650	ENTREZGENE
NCBI Gene	Abhd12b	ENTREZGENE
PANTHER	ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	PROTEIN ABHD12B	UniProtKB/TrEMBL
Pfam	Hydrolase_4	UniProtKB/TrEMBL
PhenoGen	Abhd12b	PhenoGen
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	G3UZN6	ENTREZGENE, UniProtKB/TrEMBL
	S4R1Y3_MOUSE	UniProtKB/TrEMBL
	S4R2K4_MOUSE	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Mammalian Phenotype