Trim75 (tripartite motif-containing 75) - Rat Genome Database
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Gene: Trim75 (tripartite motif-containing 75) Mus musculus
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Symbol: Trim75
Name: tripartite motif-containing 75
RGD ID: 1619692
MGI Page MGI
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to localize to cytoplasm. Orthologous to human TRIM75P (tripartite motif containing 75, pseudogene); INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Gm794; tripartite motif-containing protein 75
RGD Orthologs
Human
Pig
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm5975  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,434,303 - 65,440,296 (-)NCBIGRCm39mm39
GRCm38864,981,651 - 64,987,644 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl864,980,884 - 64,987,831 (-)EnsemblGRCm38mm10GRCm38
MGSCv37867,505,550 - 67,511,543 (-)NCBIGRCm37mm9NCBIm37
MGSCv36867,910,640 - 67,916,635 (-)NCBImm8
Celera867,543,020 - 67,549,012 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Trim75
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,434,303 - 65,440,296 (-)NCBIGRCm39mm39
GRCm38864,981,651 - 64,987,644 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl864,980,884 - 64,987,831 (-)EnsemblGRCm38mm10GRCm38
MGSCv37867,505,550 - 67,511,543 (-)NCBIGRCm37mm9NCBIm37
MGSCv36867,910,640 - 67,916,635 (-)NCBImm8
Celera867,543,020 - 67,549,012 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
TRIM75P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4165,053,864 - 165,060,554 (+)EnsemblGRCh38hg38GRCh38
GRCh384165,058,968 - 165,060,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374165,980,120 - 165,981,714 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364166,199,750 - 166,201,156 (+)NCBINCBI36hg18NCBI36
Celera4163,311,477 - 163,313,071 (+)NCBI
Cytogenetic Map4q32.3NCBI
HuRef4161,733,390 - 161,734,984 (+)NCBIHuRef
CHM1_14165,956,622 - 165,958,216 (+)NCBICHM1_1
LOC100513415
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1844,145,897 - 44,147,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2846,150,117 - 46,151,644 (-)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1301936Trigq2_mtriglyceride QTL 2 (mouse)Not determined83383736267837502Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:221
Count of miRNA genes:199
Interacting mature miRNAs:204
Transcripts:ENSMUST00000095295
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000095295   ⟹   ENSMUSP00000092932
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl864,980,884 - 64,987,646 (-)Ensembl
RefSeq Acc Id: ENSMUST00000210982   ⟹   ENSMUSP00000148052
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl864,983,718 - 64,987,831 (-)Ensembl
RefSeq Acc Id: NM_001033429   ⟹   NP_001028601
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39865,434,303 - 65,440,296 (-)NCBI
GRCm38864,981,651 - 64,987,644 (-)NCBI
MGSCv37867,505,550 - 67,511,543 (-)RGD
Celera867,543,020 - 67,549,012 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001028601   ⟸   NM_001033429
- UniProtKB: Q3UWZ0 (UniProtKB/Swiss-Prot),   B2RTB3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000148052   ⟸   ENSMUST00000210982
RefSeq Acc Id: ENSMUSP00000092932   ⟸   ENSMUST00000095295
Protein Domains
B box-type   B30.2/SPRY   RING-type


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2685640 AgrOrtholog
Ensembl Genes ENSMUSG00000071089 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000092932 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148052 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000095295 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000210982 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY/PRY_TRIM75 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_B-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:333307 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2685640 ENTREZGENE
NCBI Gene 333307 ENTREZGENE
Pfam PRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-B_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trim75 PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.334557 ENTREZGENE
UniProt A0A1B0GSS5_MOUSE UniProtKB/TrEMBL
  B2RTB3 ENTREZGENE, UniProtKB/TrEMBL
  Q3TQX4_MOUSE UniProtKB/TrEMBL
  Q3TSB1_MOUSE UniProtKB/TrEMBL
  Q3UWZ0 ENTREZGENE, UniProtKB/Swiss-Prot