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Gene: Trp53rka (transformation related protein 53 regulating kinase A) Mus musculus
Symbol: Trp53rka
Name: transformation related protein 53 regulating kinase A
Description: Predicted to have p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to localize to the EKC/KEOPS complex; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Is expressed in embryo. Orthologous to human TP53RK (TP53 regulating kinase); INTERACTS WITH (+)-schisandrin B (ortholog); 17beta-estradiol (ortholog); 2-hydroxypropanoic acid (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810408M09Rik; hypothetical protein LOC381406; MGC102419; novel protein similar to Trp53 regulating kinase (Trp53rk); RP23-395E18.2; TP53-regulating kinase; uncharacterized protein LOC381406
Homo sapiens (human) : TP53RK (TP53 regulating kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tp53rk (TP53 regulating kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tp53rk (TP53 regulating kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : TP53RK (TP53 regulating kinase)
Canis lupus familiaris (dog) : TP53RK (TP53 regulating kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tp53rk (TP53 regulating kinase)
Sus scrofa (pig) : TP53RK (TP53 regulating kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382165,490,112 - 165,493,314 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372165,315,612 - 165,318,814 (-)NCBIGRCm37mm9NCBIm37
MGSCv362165,181,317 - 165,184,519 (-)NCBImm8
Celera2171,431,125 - 171,434,327 (-)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Trp53rka
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1619687
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.